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FLT-3: a new focus in the understanding of acute leukemia.
Markovic A, MacKenzie KL, Lock RB. Markovic A, et al. Among authors: lock rb. Int J Biochem Cell Biol. 2005 Jun;37(6):1168-72. doi: 10.1016/j.biocel.2004.12.005. Epub 2005 Jan 26. Int J Biochem Cell Biol. 2005. PMID: 15778081 Review.
Xenograft-directed personalized therapy for a patient with post-transplant relapse of ALL.
Trahair TN, Lock RB, Sutton R, Sia KC, Evans K, Richmond J, Law T, Venn NC, Irving JA, Moore S, Nievergall E, Dang P, Heatley SL, White DL, Revesz T. Trahair TN, et al. Among authors: lock rb. Bone Marrow Transplant. 2016 Sep;51(9):1279-82. doi: 10.1038/bmt.2016.122. Epub 2016 May 16. Bone Marrow Transplant. 2016. PMID: 27183096 No abstract available.
MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation.
Huang Y, Thoms JA, Tursky ML, Knezevic K, Beck D, Chandrakanthan V, Suryani S, Olivier J, Boulton A, Glaros EN, Thomas SR, Lock RB, MacKenzie KL, Bushweller JH, Wong JW, Pimanda JE. Huang Y, et al. Among authors: lock rb. Leukemia. 2016 Jul;30(7):1552-61. doi: 10.1038/leu.2016.55. Epub 2016 Mar 8. Leukemia. 2016. PMID: 27055868 Free PMC article.
ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer.
Thoms JA, Birger Y, Foster S, Knezevic K, Kirschenbaum Y, Chandrakanthan V, Jonquieres G, Spensberger D, Wong JW, Oram SH, Kinston SJ, Groner Y, Lock R, MacKenzie KL, Göttgens B, Izraeli S, Pimanda JE. Thoms JA, et al. Blood. 2011 Jun 30;117(26):7079-89. doi: 10.1182/blood-2010-12-317990. Epub 2011 May 2. Blood. 2011. PMID: 21536859
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