Loeb LA - Search Results

1

A high-resolution landscape of mutations in the BCL6 super-enhancer in normal human B cells.

Shen JC, Kamath-Loeb AS, Kohrn BF, Loeb KR, Preston BD, Loeb LA. Shen JC, et al. Among authors: loeb la. Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24779-24785. doi: 10.1073/pnas.1914163116. Epub 2019 Nov 20. Proc Natl Acad Sci U S A. 2019. PMID: 31748270 Free PMC article.

2

Extensive subclonal mutational diversity in human colorectal cancer and its significance.

Loeb LA, Kohrn BF, Loubet-Senear KJ, Dunn YJ, Ahn EH, O'Sullivan JN, Salk JJ, Bronner MP, Beckman RA. Loeb LA, et al. Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):26863-26872. doi: 10.1073/pnas.1910301116. Epub 2019 Dec 5. Proc Natl Acad Sci U S A. 2019. PMID: 31806761 Free PMC article.

3

Human cancers express a mutator phenotype.

Bielas JH, Loeb KR, Rubin BP, True LD, Loeb LA. Bielas JH, et al. Among authors: loeb kr, loeb la. Proc Natl Acad Sci U S A. 2006 Nov 28;103(48):18238-42. doi: 10.1073/pnas.0607057103. Epub 2006 Nov 15. Proc Natl Acad Sci U S A. 2006. PMID: 17108085 Free PMC article.

4

Werner syndrome protein interacts functionally with translesion DNA polymerases.

Kamath-Loeb AS, Lan L, Nakajima S, Yasui A, Loeb LA. Kamath-Loeb AS, et al. Among authors: loeb la. Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10394-9. doi: 10.1073/pnas.0702513104. Epub 2007 Jun 11. Proc Natl Acad Sci U S A. 2007. PMID: 17563354 Free PMC article.

5

Multiple mutations and cancer.

Loeb LA, Loeb KR, Anderson JP. Loeb LA, et al. Among authors: loeb kr. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):776-81. doi: 10.1073/pnas.0334858100. Epub 2003 Jan 27. Proc Natl Acad Sci U S A. 2003. PMID: 12552134 Free PMC article. Review.

6

Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase.

Perrino FW, Preston BD, Sandell LL, Loeb LA. Perrino FW, et al. Among authors: loeb la. Proc Natl Acad Sci U S A. 1989 Nov;86(21):8343-7. doi: 10.1073/pnas.86.21.8343. Proc Natl Acad Sci U S A. 1989. PMID: 2479023 Free PMC article.

7

Sphingosine, a modulator of human translesion DNA polymerase activity.

Kamath-Loeb AS, Balakrishna S, Whittington D, Shen JC, Emond MJ, Okabe T, Masutani C, Hanaoka F, Nishimura S, Loeb LA. Kamath-Loeb AS, et al. Among authors: loeb la. J Biol Chem. 2014 Aug 1;289(31):21663-72. doi: 10.1074/jbc.M114.570242. Epub 2014 Jun 13. J Biol Chem. 2014. PMID: 24928506 Free PMC article.

8

Detecting ultralow-frequency mutations by Duplex Sequencing.

Kennedy SR, Schmitt MW, Fox EJ, Kohrn BF, Salk JJ, Ahn EH, Prindle MJ, Kuong KJ, Shen JC, Risques RA, Loeb LA. Kennedy SR, et al. Among authors: loeb la. Nat Protoc. 2014 Nov;9(11):2586-606. doi: 10.1038/nprot.2014.170. Epub 2014 Oct 9. Nat Protoc. 2014. PMID: 25299156 Free PMC article.

9

Detection of Ultra-Rare Mitochondrial Mutations in Breast Stem Cells by Duplex Sequencing.

Ahn EH, Hirohata K, Kohrn BF, Fox EJ, Chang CC, Loeb LA. Ahn EH, et al. Among authors: loeb la. PLoS One. 2015 Aug 25;10(8):e0136216. doi: 10.1371/journal.pone.0136216. eCollection 2015. PLoS One. 2015. PMID: 26305705 Free PMC article.

10

PolyG-DS: An ultrasensitive polyguanine tract-profiling method to detect clonal expansions and trace cell lineage.

Zhang Y, Kohrn BF, Yang M, Nachmanson D, Soong TR, Lee IH, Tao Y, Clevers H, Swisher EM, Brentnall TA, Loeb LA, Kennedy SR, Salk JJ, Naxerova K, Risques RA. Zhang Y, et al. Among authors: loeb la. Proc Natl Acad Sci U S A. 2021 Aug 3;118(31):e2023373118. doi: 10.1073/pnas.2023373118. Proc Natl Acad Sci U S A. 2021. PMID: 34330826 Free PMC article.

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