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Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression.
Trudu M, Janas S, Lanzani C, Debaix H, Schaeffer C, Ikehata M, Citterio L, Demaretz S, Trevisani F, Ristagno G, Glaudemans B, Laghmani K, Dell'Antonio G; SKIPOGH team; Loffing J, Rastaldi MP, Manunta P, Devuyst O, Rampoldi L. Trudu M, et al. Among authors: loffing j. Nat Med. 2013 Dec;19(12):1655-60. doi: 10.1038/nm.3384. Epub 2013 Nov 3. Nat Med. 2013. PMID: 24185693 Free PMC article.
Renal expression of parvalbumin is critical for NaCl handling and response to diuretics.
Belge H, Gailly P, Schwaller B, Loffing J, Debaix H, Riveira-Munoz E, Beauwens R, Devogelaer JP, Hoenderop JG, Bindels RJ, Devuyst O. Belge H, et al. Among authors: loffing j. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14849-54. doi: 10.1073/pnas.0702810104. Epub 2007 Sep 5. Proc Natl Acad Sci U S A. 2007. PMID: 17804801 Free PMC article.
In vivo nuclear translocation of mineralocorticoid and glucocorticoid receptors in rat kidney: differential effect of corticosteroids along the distal tubule.
Ackermann D, Gresko N, Carrel M, Loffing-Cueni D, Habermehl D, Gomez-Sanchez C, Rossier BC, Loffing J. Ackermann D, et al. Among authors: loffing cueni d, loffing j. Am J Physiol Renal Physiol. 2010 Dec;299(6):F1473-85. doi: 10.1152/ajprenal.00437.2010. Epub 2010 Sep 22. Am J Physiol Renal Physiol. 2010. PMID: 20861076 Free article.
Aldosterone deficiency adversely affects pregnancy outcome in mice.
Todkar A, Di Chiara M, Loffing-Cueni D, Bettoni C, Mohaupt M, Loffing J, Wagner CA. Todkar A, et al. Among authors: loffing cueni d, loffing j. Pflugers Arch. 2012 Oct;464(4):331-43. doi: 10.1007/s00424-012-1145-4. Epub 2012 Sep 2. Pflugers Arch. 2012. PMID: 22941338 Free article.
Parvalbumin: calcium and magnesium buffering in the distal nephron.
Olinger E, Schwaller B, Loffing J, Gailly P, Devuyst O. Olinger E, et al. Among authors: loffing j. Nephrol Dial Transplant. 2012 Nov;27(11):3988-94. doi: 10.1093/ndt/gfs457. Nephrol Dial Transplant. 2012. PMID: 23144069 Free article. Review.
Common variants in UMOD associate with urinary uromodulin levels: a meta-analysis.
Olden M, Corre T, Hayward C, Toniolo D, Ulivi S, Gasparini P, Pistis G, Hwang SJ, Bergmann S, Campbell H, Cocca M, Gandin I, Girotto G, Glaudemans B, Hastie ND, Loffing J, Polasek O, Rampoldi L, Rudan I, Sala C, Traglia M, Vollenweider P, Vuckovic D, Youhanna S, Weber J, Wright AF, Kutalik Z, Bochud M, Fox CS, Devuyst O. Olden M, et al. Among authors: loffing j. J Am Soc Nephrol. 2014 Aug;25(8):1869-82. doi: 10.1681/ASN.2013070781. Epub 2014 Feb 27. J Am Soc Nephrol. 2014. PMID: 24578125 Free PMC article.
ENaC activity in collecting ducts modulates NCC in cirrhotic mice.
Mordasini D, Loffing-Cueni D, Loffing J, Beatrice R, Maillard MP, Hummler E, Burnier M, Escher G, Vogt B. Mordasini D, et al. Among authors: loffing cueni d, loffing j. Pflugers Arch. 2015 Dec;467(12):2529-39. doi: 10.1007/s00424-015-1711-7. Epub 2015 Jun 10. Pflugers Arch. 2015. PMID: 26055235 Free article.
Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney.
Di Chiara M, Glaudemans B, Loffing-Cueni D, Odermatt A, Al-Hasani H, Devuyst O, Faresse N, Loffing J. Di Chiara M, et al. Among authors: loffing cueni d, loffing j. Am J Physiol Renal Physiol. 2015 Nov 1;309(9):F779-90. doi: 10.1152/ajprenal.00139.2015. Epub 2015 Sep 2. Am J Physiol Renal Physiol. 2015. PMID: 26336159 Free article.
152 results