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Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension.
Nat Med. 2019 Nov;25(11):1733-1738. doi: 10.1038/s41591-019-0622-0. Epub 2019 Nov 7.
Nat Med. 2019.
PMID: 31700171
Free PMC article.
Contribution of heterozygous PCSK1 variants to obesity and implications for precision medicine: a case-control study.
Folon L, Baron M, Toussaint B, Vaillant E, Boissel M, Scherrer V, Loiselle H, Leloire A, Badreddine A, Balkau B, Charpentier G, Franc S, Marre M, Aboulouard S, Salzet M, Canouil M, Derhourhi M, Froguel P, Bonnefond A.
Folon L, et al. Among authors: loiselle h.
Lancet Diabetes Endocrinol. 2023 Mar;11(3):182-190. doi: 10.1016/S2213-8587(22)00392-8.
Lancet Diabetes Endocrinol. 2023.
PMID: 36822744
Free article.
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Pathogenic monoallelic variants in GLIS3 increase type 2 diabetes risk and identify a subgroup of patients sensitive to sulfonylureas.
Meulebrouck S, Scherrer V, Boutry R, Toussaint B, Vaillant E, Dechaume A, Loiselle H, Balkau B, Charpentier G, Franc S, Marre M, Baron M, Vaxillaire M, Derhourhi M, Boissel M, Froguel P, Bonnefond A.
Meulebrouck S, et al. Among authors: loiselle h.
Diabetologia. 2024 Feb;67(2):327-332. doi: 10.1007/s00125-023-06035-x. Epub 2023 Dec 5.
Diabetologia. 2024.
PMID: 38051360
Free PMC article.
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Pathogenic, Total Loss-of-Function DYRK1B Variants Cause Monogenic Obesity Associated With Type 2 Diabetes.
Folon L, Baron M, Scherrer V, Toussaint B, Vaillant E, Loiselle H, Dechaume A, De Pooter F, Boutry R, Boissel M, Diallo A, Ning L, Balkau B, Charpentier G, Franc S, Marre M, Derhourhi M, Froguel P, Bonnefond A.
Folon L, et al. Among authors: loiselle h.
Diabetes Care. 2024 Mar 1;47(3):444-451. doi: 10.2337/dc23-1851.
Diabetes Care. 2024.
PMID: 38170957
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Exploring the role of purinergic receptor P2RY1 in type 2 diabetes risk and pathophysiology: Insights from human functional genomics.
Dance A, Fernandes J, Toussaint B, Vaillant E, Boutry R, Baron M, Loiselle H, Balkau B, Charpentier G, Franc S, Ibberson M, Marre M, Gernay M, Fadeur M, Paquot N, Vaxillaire M, Boissel M, Amanzougarene S, Derhourhi M, Khamis A, Froguel P, Bonnefond A.
Dance A, et al. Among authors: loiselle h.
Mol Metab. 2024 Jan;79:101867. doi: 10.1016/j.molmet.2023.101867. Epub 2023 Dec 28.
Mol Metab. 2024.
PMID: 38159881
Free PMC article.
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Phylogenomic analysis points to a South American origin of Manihot and illuminates the primary gene pool of cassava.
Simon MF, Mendoza Flores JM, Liu HL, Martins MLL, Drovetski SV, Przelomska NAS, Loiselle H, Cavalcanti TB, Inglis PW, Mueller NG, Allaby RG, Freitas FO, Kistler L.
Simon MF, et al. Among authors: loiselle h.
New Phytol. 2022 Jan;233(1):534-545. doi: 10.1111/nph.17743. Epub 2021 Oct 18.
New Phytol. 2022.
PMID: 34537964
Free article.
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Multiproxy evidence highlights a complex evolutionary legacy of maize in South America.
Kistler L, Maezumi SY, Gregorio de Souza J, Przelomska NAS, Malaquias Costa F, Smith O, Loiselle H, Ramos-Madrigal J, Wales N, Ribeiro ER, Morrison RR, Grimaldo C, Prous AP, Arriaza B, Gilbert MTP, de Oliveira Freitas F, Allaby RG.
Kistler L, et al. Among authors: loiselle h.
Science. 2018 Dec 14;362(6420):1309-1313. doi: 10.1126/science.aav0207.
Science. 2018.
PMID: 30545889
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