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Study protocol of a phase 2, dual-centre, randomised, controlled trial evaluating the effectiveness of probiotic and egg oral immunotherapy at inducing desensitisation or sustained unresponsiveness (remission) in participants with egg allergy compared with placebo (Probiotic Egg Allergen Oral Immunotherapy for Treatment of Egg Allergy: PEAT study).
Loke P, Chebar Lozinsky A, Orsini F, Wong LS, Leung AS, Tham EH, Lopata AL, Shek LP, Tang ML; PEAT study team. Loke P, et al. BMJ Open. 2021 Jul 7;11(7):e044331. doi: 10.1136/bmjopen-2020-044331. BMJ Open. 2021. PMID: 34233966 Free PMC article.
Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis.
Weinstock A, Rahman K, Yaacov O, Nishi H, Menon P, Nikain CA, Garabedian ML, Pena S, Akbar N, Sansbury BE, Heffron SP, Liu J, Marecki G, Fernandez D, Brown EJ, Ruggles KV, Ramsey SA, Giannarelli C, Spite M, Choudhury RP, Loke P, Fisher EA. Weinstock A, et al. Among authors: loke p. Elife. 2021 Mar 15;10:e67932. doi: 10.7554/eLife.67932. Elife. 2021. PMID: 33720008 Free PMC article.
The helminth glycoprotein omega-1 improves metabolic homeostasis in obese mice through type 2 immunity-independent inhibition of food intake.
van der Zande HJP, Gonzalez MA, de Ruiter K, Wilbers RHP, García-Tardón N, van Huizen M, van Noort K, Pelgrom LR, Lambooij JM, Zawistowska-Deniziak A, Otto F, Ozir-Fazalalikhan A, van Willigen D, Welling M, Poles J, van Leeuwen F, Hokke CH, Schots A, Yazdanbakhsh M, Loke P, Guigas B. van der Zande HJP, et al. Among authors: loke p. FASEB J. 2021 Feb;35(2):e21331. doi: 10.1096/fj.202001973R. FASEB J. 2021. PMID: 33476078 Free PMC article.
Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease.
Lee JY, Hall JA, Kroehling L, Wu L, Najar T, Nguyen HH, Lin WY, Yeung ST, Silva HM, Li D, Hine A, Loke P, Hudesman D, Martin JC, Kenigsberg E, Merad M, Khanna KM, Littman DR. Lee JY, et al. Among authors: loke p. Cell. 2020 Dec 23;183(7):2036-2039. doi: 10.1016/j.cell.2020.12.008. Cell. 2020. PMID: 33357400 Free PMC article. No abstract available.
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