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The first identification of lysine malonylation substrates and its regulatory enzyme.
Peng C, Lu Z, Xie Z, Cheng Z, Chen Y, Tan M, Luo H, Zhang Y, He W, Yang K, Zwaans BM, Tishkoff D, Ho L, Lombard D, He TC, Dai J, Verdin E, Ye Y, Zhao Y. Peng C, et al. Among authors: lombard d. Mol Cell Proteomics. 2011 Dec;10(12):M111.012658. doi: 10.1074/mcp.M111.012658. Epub 2011 Sep 9. Mol Cell Proteomics. 2011. PMID: 21908771 Free PMC article.
Proteomic and Biochemical Studies of Lysine Malonylation Suggest Its Malonic Aciduria-associated Regulatory Role in Mitochondrial Function and Fatty Acid Oxidation.
Colak G, Pougovkina O, Dai L, Tan M, Te Brinke H, Huang H, Cheng Z, Park J, Wan X, Liu X, Yue WW, Wanders RJ, Locasale JW, Lombard DB, de Boer VC, Zhao Y. Colak G, et al. Mol Cell Proteomics. 2015 Nov;14(11):3056-71. doi: 10.1074/mcp.M115.048850. Epub 2015 Aug 28. Mol Cell Proteomics. 2015. PMID: 26320211 Free PMC article.
Lysine glutarylation is a protein posttranslational modification regulated by SIRT5.
Tan M, Peng C, Anderson KA, Chhoy P, Xie Z, Dai L, Park J, Chen Y, Huang H, Zhang Y, Ro J, Wagner GR, Green MF, Madsen AS, Schmiesing J, Peterson BS, Xu G, Ilkayeva OR, Muehlbauer MJ, Braulke T, Mühlhausen C, Backos DS, Olsen CA, McGuire PJ, Pletcher SD, Lombard DB, Hirschey MD, Zhao Y. Tan M, et al. Among authors: lombard db. Cell Metab. 2014 Apr 1;19(4):605-17. doi: 10.1016/j.cmet.2014.03.014. Cell Metab. 2014. PMID: 24703693 Free PMC article.
Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation.
Xie Z, Zhang D, Chung D, Tang Z, Huang H, Dai L, Qi S, Li J, Colak G, Chen Y, Xia C, Peng C, Ruan H, Kirkey M, Wang D, Jensen LM, Kwon OK, Lee S, Pletcher SD, Tan M, Lombard DB, White KP, Zhao H, Li J, Roeder RG, Yang X, Zhao Y. Xie Z, et al. Among authors: lombard db. Mol Cell. 2016 Apr 21;62(2):194-206. doi: 10.1016/j.molcel.2016.03.036. Mol Cell. 2016. PMID: 27105115 Free PMC article.
ACSF3 and Mal(onate)-Adapted Mitochondria.
Lombard DB, Zhao Y. Lombard DB, et al. Cell Chem Biol. 2017 Jun 22;24(6):649-650. doi: 10.1016/j.chembiol.2017.06.004. Cell Chem Biol. 2017. PMID: 28644952 Free article.
SIRT3: as simple as it seems?
Lombard DB, Zwaans BM. Lombard DB, et al. Gerontology. 2014;60(1):56-64. doi: 10.1159/000354382. Epub 2013 Oct 25. Gerontology. 2014. PMID: 24192814 Free PMC article. Review.
133 results