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313 results
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Targeting BRAF for patients with melanoma.
Arkenau HT, Kefford R, Long GV. Arkenau HT, et al. Among authors: long gv. Br J Cancer. 2011 Feb 1;104(3):392-8. doi: 10.1038/sj.bjc.6606030. Epub 2010 Dec 7. Br J Cancer. 2011. PMID: 21139585 Free PMC article. Review.
Prognostic and clinicopathologic associations of oncogenic BRAF in metastatic melanoma.
Long GV, Menzies AM, Nagrial AM, Haydu LE, Hamilton AL, Mann GJ, Hughes TM, Thompson JF, Scolyer RA, Kefford RF. Long GV, et al. J Clin Oncol. 2011 Apr 1;29(10):1239-46. doi: 10.1200/JCO.2010.32.4327. Epub 2011 Feb 22. J Clin Oncol. 2011. PMID: 21343559
Evolving concepts in melanoma classification and their relevance to multidisciplinary melanoma patient care.
Scolyer RA, Long GV, Thompson JF. Scolyer RA, et al. Among authors: long gv. Mol Oncol. 2011 Apr;5(2):124-36. doi: 10.1016/j.molonc.2011.03.002. Epub 2011 Mar 21. Mol Oncol. 2011. PMID: 21482206 Free PMC article. Review.
Selective BRAF inhibitors induce marked T-cell infiltration into human metastatic melanoma.
Wilmott JS, Long GV, Howle JR, Haydu LE, Sharma RN, Thompson JF, Kefford RF, Hersey P, Scolyer RA. Wilmott JS, et al. Among authors: long gv. Clin Cancer Res. 2012 Mar 1;18(5):1386-94. doi: 10.1158/1078-0432.CCR-11-2479. Epub 2011 Dec 12. Clin Cancer Res. 2012. PMID: 22156613
Clinical and pathologic factors associated with distant metastasis and survival in patients with thin primary cutaneous melanoma.
Murali R, Haydu LE, Long GV, Quinn MJ, Saw RP, Shannon K, Spillane AJ, Stretch JR, Kefford RF, Thompson JF, Scolyer RA. Murali R, et al. Among authors: long gv. Ann Surg Oncol. 2012 Jun;19(6):1782-9. doi: 10.1245/s10434-012-2265-y. Epub 2012 Feb 14. Ann Surg Oncol. 2012. PMID: 22350600 Clinical Trial.
Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance.
Shi H, Moriceau G, Kong X, Lee MK, Lee H, Koya RC, Ng C, Chodon T, Scolyer RA, Dahlman KB, Sosman JA, Kefford RF, Long GV, Nelson SF, Ribas A, Lo RS. Shi H, et al. Among authors: long gv. Nat Commun. 2012 Mar 6;3:724. doi: 10.1038/ncomms1727. Nat Commun. 2012. PMID: 22395615 Free PMC article.
The development of acquired drug resistance hampers the long-term success of B-RAF inhibitor therapy for melanoma patients. Here we show (V600E)B-RAF copy-number gain as a mechanism of acquired B-RAF inhibitor resistance in 4 out of 20 (20%) patients treated with B-RAF inh …
The development of acquired drug resistance hampers the long-term success of B-RAF inhibitor therapy for melanoma patients. Here we s …
Treatment of melanoma brain metastases: a new paradigm.
Carlino MS, Fogarty GB, Long GV. Carlino MS, et al. Among authors: long gv. Cancer J. 2012 Mar-Apr;18(2):208-12. doi: 10.1097/PPO.0b013e31824b2890. Cancer J. 2012. PMID: 22453023 Review.
Distinguishing clinicopathologic features of patients with V600E and V600K BRAF-mutant metastatic melanoma.
Menzies AM, Haydu LE, Visintin L, Carlino MS, Howle JR, Thompson JF, Kefford RF, Scolyer RA, Long GV. Menzies AM, et al. Among authors: long gv. Clin Cancer Res. 2012 Jun 15;18(12):3242-9. doi: 10.1158/1078-0432.CCR-12-0052. Epub 2012 Apr 24. Clin Cancer Res. 2012. PMID: 22535154
Preexisting MEK1 exon 3 mutations in V600E/KBRAF melanomas do not confer resistance to BRAF inhibitors.
Shi H, Moriceau G, Kong X, Koya RC, Nazarian R, Pupo GM, Bacchiocchi A, Dahlman KB, Chmielowski B, Sosman JA, Halaban R, Kefford RF, Long GV, Ribas A, Lo RS. Shi H, et al. Among authors: long gv. Cancer Discov. 2012 May;2(5):414-24. doi: 10.1158/2159-8290.CD-12-0022. Epub 2012 Apr 1. Cancer Discov. 2012. PMID: 22588879 Free PMC article.
Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial.
Falchook GS, Long GV, Kurzrock R, Kim KB, Arkenau TH, Brown MP, Hamid O, Infante JR, Millward M, Pavlick AC, O'Day SJ, Blackman SC, Curtis CM, Lebowitz P, Ma B, Ouellet D, Kefford RF. Falchook GS, et al. Among authors: long gv. Lancet. 2012 May 19;379(9829):1893-901. doi: 10.1016/S0140-6736(12)60398-5. Lancet. 2012. PMID: 22608338 Free PMC article. Clinical Trial.
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