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Mutations in ribosomal protein L3 and 23S ribosomal RNA at the peptidyl transferase centre are associated with reduced susceptibility to tiamulin in Brachyspira spp. isolates.
Pringle M, Poehlsgaard J, Vester B, Long KS. Pringle M, et al. Among authors: long ks. Mol Microbiol. 2004 Dec;54(5):1295-306. doi: 10.1111/j.1365-2958.2004.04373.x. Mol Microbiol. 2004. PMID: 15554969
Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance.
Long KS, Munck C, Andersen TM, Schaub MA, Hobbie SN, Böttger EC, Vester B. Long KS, et al. Antimicrob Agents Chemother. 2010 Nov;54(11):4705-13. doi: 10.1128/AAC.00644-10. Epub 2010 Aug 9. Antimicrob Agents Chemother. 2010. PMID: 20696869 Free PMC article.
Interaction of pleuromutilin derivatives with the ribosomal peptidyl transferase center.
Long KS, Hansen LH, Jakobsen L, Vester B. Long KS, et al. Antimicrob Agents Chemother. 2006 Apr;50(4):1458-62. doi: 10.1128/AAC.50.4.1458-1462.2006. Antimicrob Agents Chemother. 2006. PMID: 16569865 Free PMC article.
Resistance to the peptidyl transferase inhibitor tiamulin caused by mutation of ribosomal protein l3.
Bøsling J, Poulsen SM, Vester B, Long KS. Bøsling J, et al. Among authors: long ks. Antimicrob Agents Chemother. 2003 Sep;47(9):2892-6. doi: 10.1128/aac.47.9.2892-2896.2003. Antimicrob Agents Chemother. 2003. PMID: 12936991 Free PMC article.
Single 23S rRNA mutations at the ribosomal peptidyl transferase centre confer resistance to valnemulin and other antibiotics in Mycobacterium smegmatis by perturbation of the drug binding pocket.
Long KS, Poehlsgaard J, Hansen LH, Hobbie SN, Böttger EC, Vester B. Long KS, et al. Mol Microbiol. 2009 Mar;71(5):1218-27. doi: 10.1111/j.1365-2958.2009.06596.x. Epub 2009 Jan 16. Mol Microbiol. 2009. PMID: 19154331
A conserved chloramphenicol binding site at the entrance to the ribosomal peptide exit tunnel.
Long KS, Porse BT. Long KS, et al. Nucleic Acids Res. 2003 Dec 15;31(24):7208-15. doi: 10.1093/nar/gkg945. Nucleic Acids Res. 2003. PMID: 14654696 Free PMC article.
Insights into the structure, function and evolution of the radical-SAM 23S rRNA methyltransferase Cfr that confers antibiotic resistance in bacteria.
Kaminska KH, Purta E, Hansen LH, Bujnicki JM, Vester B, Long KS. Kaminska KH, et al. Among authors: long ks. Nucleic Acids Res. 2010 Mar;38(5):1652-63. doi: 10.1093/nar/gkp1142. Epub 2009 Dec 10. Nucleic Acids Res. 2010. PMID: 20007606 Free PMC article.
Resistance to linezolid caused by modifications at its binding site on the ribosome.
Long KS, Vester B. Long KS, et al. Antimicrob Agents Chemother. 2012 Feb;56(2):603-12. doi: 10.1128/AAC.05702-11. Epub 2011 Dec 5. Antimicrob Agents Chemother. 2012. PMID: 22143525 Free PMC article. Review.
Identification of 8-methyladenosine as the modification catalyzed by the radical SAM methyltransferase Cfr that confers antibiotic resistance in bacteria.
Giessing AM, Jensen SS, Rasmussen A, Hansen LH, Gondela A, Long K, Vester B, Kirpekar F. Giessing AM, et al. Among authors: long k. RNA. 2009 Feb;15(2):327-36. doi: 10.1261/rna.1371409. RNA. 2009. PMID: 19144912 Free PMC article.
Puromycin-rRNA interaction sites at the peptidyl transferase center.
Rodriguez-Fonseca C, Phan H, Long KS, Porse BT, Kirillov SV, Amils R, Garrett RA. Rodriguez-Fonseca C, et al. Among authors: long ks. RNA. 2000 May;6(5):744-54. doi: 10.1017/s1355838200000091. RNA. 2000. PMID: 10836795 Free PMC article.
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