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| Year | Number of Results |
|---|---|
| 2000 | 1 |
| 2009 | 1 |
| 2010 | 1 |
| 2014 | 2 |
| 2018 | 1 |
| 2019 | 2 |
| 2020 | 1 |
| 2022 | 2 |
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Long-term coffee consumption, caffeine metabolism genetics, and risk of cardiovascular disease: a prospective analysis of up to 347,077 individuals and 8368 cases.
Am J Clin Nutr. 2019 Mar 1;109(3):509-516. doi: 10.1093/ajcn/nqy297.
Am J Clin Nutr. 2019.
PMID: 30838377
Free article.
However, increased risk of myocardial infarction and hypertension has been suggested for individuals who carry a functional variant at cytochrome P450 1A2 (CYP1A2), which makes them less effective at metabolizing caffeine. OBJECTIVES: The aim of this study was to ex …
However, increased risk of myocardial infarction and hypertension has been suggested for individuals who carry a functional variant at cytoc …
Metabolomic Signatures of Long-term Coffee Consumption and Risk of Type 2 Diabetes in Women.
Diabetes Care. 2020 Oct;43(10):2588-2596. doi: 10.2337/dc20-0800. Epub 2020 Aug 11.
Diabetes Care. 2020.
PMID: 32788283
Free PMC article.
These associations were generally consistent for caffeinated and decaffeinated coffee, except for caffeine and its metabolites that were only associated with caffeinated coffee intake. ...Similar improvement was observed in the validation set. C …
These associations were generally consistent for caffeinated and decaffeinated coffee, except for caffeine and its meta …
Tea, coffee, caffeine intake and the risk of cardio-metabolic outcomes: findings from a population with low coffee and high tea consumption.
Nutr Metab (Lond). 2019 May 3;16:28. doi: 10.1186/s12986-019-0355-6. eCollection 2019.
Nutr Metab (Lond). 2019.
PMID: 31073321
Free PMC article.
BACKGROUND: This study aimed to assess the potential effects of long-term intake of caffeine and habitual consumption of coffee and tea on the occurrence of cardio-renal events among an Iranian population with low coffee and high tea c …
BACKGROUND: This study aimed to assess the potential effects of long-term intake of caffeine and habitual consumptio …
Caffeine, adenosine receptors, and synaptic plasticity.
J Alzheimers Dis. 2010;20 Suppl 1:S25-34. doi: 10.3233/JAD-2010-091384.
J Alzheimers Dis. 2010.
PMID: 20182030
Free article.
Review.
Few studies to date have looked at the effects of caffeine on synaptic plasticity, and those that did used very high concentrations of caffeine, whereas the brain concentrations attained by regular coffee consumption in humans should be in the low micr …
Few studies to date have looked at the effects of caffeine on synaptic plasticity, and those that did used very high concentrations o …
Current evidence for the use of coffee and caffeine to prevent age-related cognitive decline and Alzheimer's disease.
J Nutr Health Aging. 2014 Apr;18(4):383-92. doi: 10.1007/s12603-014-0021-7.
J Nutr Health Aging. 2014.
PMID: 24676319
Free article.
Review.
Although nothing has been proven conclusively to protect against cognitive aging, Alzheimer's disease or related dementias, decades of research suggest that specific approaches including the consumption of coffee may be effective. While coffee and caffeine …
Although nothing has been proven conclusively to protect against cognitive aging, Alzheimer's disease or related dementias, decades of resea …
Sex-specific impacts of caffeine on body composition: commentary on a retrospective cohort study.
J Int Soc Sports Nutr. 2025 Dec;22(1):2454633. doi: 10.1080/15502783.2025.2454633. Epub 2025 Jan 17.
J Int Soc Sports Nutr. 2025.
PMID: 39825466
Free PMC article.
METHODS: This letter to editor builds on the findings of Tian et al., drawing from related literature and prior research to contextualize the potential mechanisms and broader implications of caffeine's impact on body composition. The discussion highlights key areas …
METHODS: This letter to editor builds on the findings of Tian et al., drawing from related literature and prior research to contextualize th …
[Side effects of caffeine].
Pol Merkur Lekarski. 2009 Nov;27(161):357-61.
Pol Merkur Lekarski. 2009.
PMID: 19999796
Polish.
Caffeine is one of the most commonly ingested alkaloids worldwide. It is present in coffee, tea, soft and energy drinks, chocolate, etc. ...The acute high consumption may also modulate insulin sensitivity and glucose blood level. However, the long-t …
Caffeine is one of the most commonly ingested alkaloids worldwide. It is present in coffee, tea, soft and energy drinks, choco …
Caffeine-Induced Sleep Restriction Alters the Gut Microbiome and Fecal Metabolic Profiles in Mice.
Int J Mol Sci. 2022 Nov 27;23(23):14837. doi: 10.3390/ijms232314837.
Int J Mol Sci. 2022.
PMID: 36499163
Free PMC article.
Insufficient sleep is becoming increasingly common and contributes to many health issues. To combat sleepiness, caffeine is consumed daily worldwide. Thus, caffeine consumption and sleep restriction often occur in succession. ...In conclusion, a long- …
Insufficient sleep is becoming increasingly common and contributes to many health issues. To combat sleepiness, caffeine is consumed …
Habitual coffee consumption and cognitive function: a Mendelian randomization meta-analysis in up to 415,530 participants.
Sci Rep. 2018 May 14;8(1):7526. doi: 10.1038/s41598-018-25919-2.
Sci Rep. 2018.
PMID: 29760501
Free PMC article.
Coffee's long-term effect on cognitive function remains unclear with studies suggesting both benefits and adverse effects. ...Despite the power to detect very small effects, our meta-analysis provided no evidence for causal long-term effe …
Coffee's long-term effect on cognitive function remains unclear with studies suggesting both benefits and advers …
Thebromine Targets Adenosine Receptors to Control Hippocampal Neuronal Function and Damage.
Int J Mol Sci. 2022 Sep 10;23(18):10510. doi: 10.3390/ijms231810510.
Int J Mol Sci. 2022.
PMID: 36142422
Free PMC article.
Theobromine is a caffeine metabolite most abundant in dark chocolate, of which consumption is linked with a lower risk of cognitive decline. ...Theobromine (30 muM) facilitated synaptic transmission while decreasing the magnitude of long-term potentiat …
Theobromine is a caffeine metabolite most abundant in dark chocolate, of which consumption is linked with a lower risk of cogn …
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