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Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning.
Unger EK, Keller JP, Altermatt M, Liang R, Matsui A, Dong C, Hon OJ, Yao Z, Sun J, Banala S, Flanigan ME, Jaffe DA, Hartanto S, Carlen J, Mizuno GO, Borden PM, Shivange AV, Cameron LP, Sinning S, Underhill SM, Olson DE, Amara SG, Temple Lang D, Rudnick G, Marvin JS, Lavis LD, Lester HA, Alvarez VA, Fisher AJ, Prescher JA, Kash TL, Yarov-Yarovoy V, Gradinaru V, Looger LL, Tian L. Unger EK, et al. Among authors: looger ll. Cell. 2020 Dec 23;183(7):1986-2002.e26. doi: 10.1016/j.cell.2020.11.040. Epub 2020 Dec 16. Cell. 2020. PMID: 33333022 Free PMC article.
Crystallization and preliminary X-ray characterization of the genetically encoded fluorescent calcium indicator protein GCaMP2.
Rodríguez Guilbe MM, Alfaro Malavé EC, Akerboom J, Marvin JS, Looger LL, Schreiter ER. Rodríguez Guilbe MM, et al. Among authors: looger ll. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Jul 1;64(Pt 7):629-31. doi: 10.1107/S1744309108016059. Epub 2008 Jun 11. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 18607093 Free PMC article.
A genetically encoded, high-signal-to-noise maltose sensor.
Marvin JS, Schreiter ER, Echevarría IM, Looger LL. Marvin JS, et al. Among authors: looger ll. Proteins. 2011 Nov;79(11):3025-36. doi: 10.1002/prot.23118. Proteins. 2011. PMID: 21989929 Free PMC article.
Excitation spectra and brightness optimization of two-photon excited probes.
Mütze J, Iyer V, Macklin JJ, Colonell J, Karsh B, Petrášek Z, Schwille P, Looger LL, Lavis LD, Harris TD. Mütze J, et al. Among authors: looger ll. Biophys J. 2012 Feb 22;102(4):934-44. doi: 10.1016/j.bpj.2011.12.056. Epub 2012 Feb 21. Biophys J. 2012. PMID: 22385865 Free PMC article.
155 results