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DC isoketal-modified proteins activate T cells and promote hypertension.
Kirabo A, Fontana V, de Faria AP, Loperena R, Galindo CL, Wu J, Bikineyeva AT, Dikalov S, Xiao L, Chen W, Saleh MA, Trott DW, Itani HA, Vinh A, Amarnath V, Amarnath K, Guzik TJ, Bernstein KE, Shen XZ, Shyr Y, Chen SC, Mernaugh RL, Laffer CL, Elijovich F, Davies SS, Moreno H, Madhur MS, Roberts J 2nd, Harrison DG. Kirabo A, et al. Among authors: loperena r. J Clin Invest. 2014 Oct;124(10):4642-56. doi: 10.1172/JCI74084. Epub 2014 Sep 17. J Clin Invest. 2014. PMID: 25244096 Free PMC article.
Oxidative Stress and Hypertensive Diseases.
Loperena R, Harrison DG. Loperena R, et al. Med Clin North Am. 2017 Jan;101(1):169-193. doi: 10.1016/j.mcna.2016.08.004. Epub 2016 Oct 27. Med Clin North Am. 2017. PMID: 27884227 Free PMC article. Review.
Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: roles of STAT3, interleukin 6 and hydrogen peroxide.
Loperena R, Van Beusecum JP, Itani HA, Engel N, Laroumanie F, Xiao L, Elijovich F, Laffer CL, Gnecco JS, Noonan J, Maffia P, Jasiewicz-Honkisz B, Czesnikiewicz-Guzik M, Mikolajczyk T, Sliwa T, Dikalov S, Weyand CM, Guzik TJ, Harrison DG. Loperena R, et al. Cardiovasc Res. 2018 Sep 1;114(11):1547-1563. doi: 10.1093/cvr/cvy112. Cardiovasc Res. 2018. PMID: 29800237 Free PMC article.
Sodium activates human monocytes via the NADPH oxidase and isolevuglandin formation.
Ruggeri Barbaro N, Van Beusecum J, Xiao L, do Carmo L, Pitzer A, Loperena R, Foss JD, Elijovich F, Laffer CL, Montaniel KR, Galindo CL, Chen W, Ao M, Mernaugh RL, Alsouqi A, Ikizler TA, Fogo AB, Moreno H, Zhao S, Davies SS, Harrison DG, Kirabo A. Ruggeri Barbaro N, et al. Among authors: loperena r. Cardiovasc Res. 2021 Apr 23;117(5):1358-1371. doi: 10.1093/cvr/cvaa207. Cardiovasc Res. 2021. PMID: 33038226 Free PMC article.
Highly Reactive Isolevuglandins Promote Atrial Fibrillation Caused by Hypertension.
Prinsen JK, Kannankeril PJ, Sidorova TN, Yermalitskaya LV, Boutaud O, Zagol-Ikapitte I, Barnett JV, Murphy MB, Subati T, Stark JM, Christopher IL, Jafarian-Kerman SR, Saleh MA, Norlander AE, Loperena R, Atkinson JB, Fogo AB, Luther JM, Amarnath V, Davies SS, Kirabo A, Madhur MS, Harrison DG, Murray KT. Prinsen JK, et al. Among authors: loperena r. JACC Basic Transl Sci. 2020 May 27;5(6):602-615. doi: 10.1016/j.jacbts.2020.04.004. eCollection 2020 Jun. JACC Basic Transl Sci. 2020. PMID: 32613146 Free PMC article.
Growth Arrest Specific-6 and Axl Coordinate Inflammation and Hypertension.
Van Beusecum JP, Barbaro NR, Smart CD, Patrick DM, Loperena R, Zhao S, de la Visitacion N, Ao M, Xiao L, Shibao CA, Harrison DG. Van Beusecum JP, et al. Among authors: loperena r. Circ Res. 2021 Nov 12;129(11):975-991. doi: 10.1161/CIRCRESAHA.121.319643. Epub 2021 Sep 27. Circ Res. 2021. PMID: 34565181 Free PMC article.
Geographic Variation in Obesity at the State Level in the All of Us Research Program.
Clark CR, Chandler PD, Zhou G, Noel N, Achilike C, Mendez L, O'Connor GT, Smoller JW, Weiss ST, Murphy SN, Ommerborn MJ, Karnes JH, Klimentidis YC, Jordan CD, Hiatt RA, Ramirez AH, Loperena R, Mayo K, Cohn E, Ohno-Machado L, Boerwinkle E, Cicek M, Schully SD, Mockrin S, Gebo KA, Karlson EW. Clark CR, et al. Among authors: loperena r. Prev Chronic Dis. 2021 Dec 23;18:E104. doi: 10.5888/pcd18.210094. Prev Chronic Dis. 2021. PMID: 34941480 Free PMC article.
The All of Us Research Program: Data quality, utility, and diversity.
Ramirez AH, Sulieman L, Schlueter DJ, Halvorson A, Qian J, Ratsimbazafy F, Loperena R, Mayo K, Basford M, Deflaux N, Muthuraman KN, Natarajan K, Kho A, Xu H, Wilkins C, Anton-Culver H, Boerwinkle E, Cicek M, Clark CR, Cohn E, Ohno-Machado L, Schully SD, Ahmedani BK, Argos M, Cronin RM, O'Donnell C, Fouad M, Goldstein DB, Greenland P, Hebbring SJ, Karlson EW, Khatri P, Korf B, Smoller JW, Sodeke S, Wilbanks J, Hentges J, Mockrin S, Lunt C, Devaney SA, Gebo K, Denny JC, Carroll RJ, Glazer D, Harris PA, Hripcsak G, Philippakis A, Roden DM; All of Us Research Program. Ramirez AH, et al. Among authors: loperena r. Patterns (N Y). 2022 Aug 12;3(8):100570. doi: 10.1016/j.patter.2022.100570. eCollection 2022 Aug 12. Patterns (N Y). 2022. PMID: 36033590 Free PMC article.
16 results