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ATP13A2 and Alpha-synuclein: a Metal Taste in Autophagy.
Lopes da Fonseca T, Outeiro TF. Lopes da Fonseca T, et al. Exp Neurobiol. 2014 Dec;23(4):314-23. doi: 10.5607/en.2014.23.4.314. Epub 2014 Dec 12. Exp Neurobiol. 2014. PMID: 25548531 Free PMC article. Review.
Fasudil attenuates aggregation of α-synuclein in models of Parkinson's disease.
Tatenhorst L, Eckermann K, Dambeck V, Fonseca-Ornelas L, Walle H, Lopes da Fonseca T, Koch JC, Becker S, Tönges L, Bähr M, Outeiro TF, Zweckstetter M, Lingor P. Tatenhorst L, et al. Among authors: lopes da fonseca t. Acta Neuropathol Commun. 2016 Apr 22;4:39. doi: 10.1186/s40478-016-0310-y. Acta Neuropathol Commun. 2016. PMID: 27101974 Free PMC article.
LRRK2 Promotes Tau Accumulation, Aggregation and Release.
Guerreiro PS, Gerhardt E, Lopes da Fonseca T, Bähr M, Outeiro TF, Eckermann K. Guerreiro PS, et al. Among authors: lopes da fonseca t. Mol Neurobiol. 2016 Jul;53(5):3124-3135. doi: 10.1007/s12035-015-9209-z. Epub 2015 May 27. Mol Neurobiol. 2016. PMID: 26014385
Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity.
Villar-Piqué A, Lopes da Fonseca T, Sant'Anna R, Szegö ÉM, Fonseca-Ornelas L, Pinho R, Carija A, Gerhardt E, Masaracchia C, Abad Gonzalez E, Rossetti G, Carloni P, Fernández CO, Foguel D, Milosevic I, Zweckstetter M, Ventura S, Outeiro TF. Villar-Piqué A, et al. Among authors: lopes da fonseca t. Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):E6506-E6515. doi: 10.1073/pnas.1606791113. Epub 2016 Oct 5. Proc Natl Acad Sci U S A. 2016. PMID: 27708160 Free PMC article.
α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner.
Yin G, Lopes da Fonseca T, Eisbach SE, Anduaga AM, Breda C, Orcellet ML, Szegő ÉM, Guerreiro P, Lázaro DF, Braus GH, Fernandez CO, Griesinger C, Becker S, Goody RS, Itzen A, Giorgini F, Outeiro TF, Zweckstetter M. Yin G, et al. Among authors: lopes da fonseca t. Neurobiol Dis. 2014 Oct;70:149-61. doi: 10.1016/j.nbd.2014.06.018. Epub 2014 Jun 28. Neurobiol Dis. 2014. PMID: 24983211
Membrane binding, internalization, and sorting of alpha-synuclein in the cell.
Masaracchia C, Hnida M, Gerhardt E, Lopes da Fonseca T, Villar-Pique A, Branco T, Stahlberg MA, Dean C, Fernández CO, Milosevic I, Outeiro TF. Masaracchia C, et al. Among authors: lopes da fonseca t. Acta Neuropathol Commun. 2018 Aug 14;6(1):79. doi: 10.1186/s40478-018-0578-1. Acta Neuropathol Commun. 2018. PMID: 30107856 Free PMC article.
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