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Year Number of Results
2004 2
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2007 1
2008 4
2009 5
2010 4
2011 2
2012 4
2013 6
2014 4
2015 7
2016 3
2017 3
2018 5
2019 3
2020 2
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58 results

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Page 1
Functional analysis of pathological mutations in DNA topoisomerase 3A.
Wang Y, Kaiser S, Martin-Gonzalez J, Li Y, Rasmussen LJ, Lopez-Contreras AJ, Bizard AH, Hickson ID. Wang Y, et al. Among authors: lopez contreras aj. Cell Rep. 2025 Jun 24;44(6):115764. doi: 10.1016/j.celrep.2025.115764. Epub 2025 May 30. Cell Rep. 2025. PMID: 40450688 Free article.
PICH deficiency limits the progression of MYC-induced B-cell lymphoma.
Castejón-Griñán M, Albers E, Simón-Carrasco L, Aguilera P, Sbroggio M, Pladevall-Morera D, Ingham A, Lim E, Guillen-Benitez A, Pietrini E, Lisby M, Hickson ID, Lopez-Contreras AJ. Castejón-Griñán M, et al. Among authors: lopez contreras aj. Blood Cancer J. 2024 Jan 23;14(1):16. doi: 10.1038/s41408-024-00979-y. Blood Cancer J. 2024. PMID: 38253636 Free PMC article.
Integrated analysis of FHIT gene alterations in cancer.
Simón-Carrasco L, Pietrini E, López-Contreras AJ. Simón-Carrasco L, et al. Among authors: lopez contreras aj. Cell Cycle. 2024 Jan;23(1):92-113. doi: 10.1080/15384101.2024.2304509. Epub 2024 Jan 18. Cell Cycle. 2024. PMID: 38234243 Free PMC article. Review.
ATRX, a guardian of chromatin.
Aguilera P, López-Contreras AJ. Aguilera P, et al. Among authors: lopez contreras aj. Trends Genet. 2023 Jun;39(6):505-519. doi: 10.1016/j.tig.2023.02.009. Epub 2023 Mar 7. Trends Genet. 2023. PMID: 36894374 Free article. Review.
Genetic insights into biological mechanisms governing human ovarian ageing.
Ruth KS, Day FR, Hussain J, Martínez-Marchal A, Aiken CE, Azad A, Thompson DJ, Knoblochova L, Abe H, Tarry-Adkins JL, Gonzalez JM, Fontanillas P, Claringbould A, Bakker OB, Sulem P, Walters RG, Terao C, Turon S, Horikoshi M, Lin K, Onland-Moret NC, Sankar A, Hertz EPT, Timshel PN, Shukla V, Borup R, Olsen KW, Aguilera P, Ferrer-Roda M, Huang Y, Stankovic S, Timmers PRHJ, Ahearn TU, Alizadeh BZ, Naderi E, Andrulis IL, Arnold AM, Aronson KJ, Augustinsson A, Bandinelli S, Barbieri CM, Beaumont RN, Becher H, Beckmann MW, Benonisdottir S, Bergmann S, Bochud M, Boerwinkle E, Bojesen SE, Bolla MK, Boomsma DI, Bowker N, Brody JA, Broer L, Buring JE, Campbell A, Campbell H, Castelao JE, Catamo E, Chanock SJ, Chenevix-Trench G, Ciullo M, Corre T, Couch FJ, Cox A, Crisponi L, Cross SS, Cucca F, Czene K, Smith GD, de Geus EJCN, de Mutsert R, De Vivo I, Demerath EW, Dennis J, Dunning AM, Dwek M, Eriksson M, Esko T, Fasching PA, Faul JD, Ferrucci L, Franceschini N, Frayling TM, Gago-Dominguez M, Mezzavilla M, García-Closas M, Gieger C, Giles GG, Grallert H, Gudbjartsson DF, Gudnason V, Guénel P, Haiman CA, Håkansson N, Hall P, Hayward C, He C, He W, Heiss G, Høffding MK, Hopper JL, Hottenga JJ,… See abstract for full author list ➔ Ruth KS, et al. Among authors: lopez contreras aj. Nature. 2021 Aug;596(7872):393-397. doi: 10.1038/s41586-021-03779-7. Epub 2021 Aug 4. Nature. 2021. PMID: 34349265 Free PMC article.
ATR expands embryonic stem cell fate potential in response to replication stress.
Atashpaz S, Samadi Shams S, Gonzalez JM, Sebestyén E, Arghavanifard N, Gnocchi A, Albers E, Minardi S, Faga G, Soffientini P, Allievi E, Cancila V, Bachi A, Fernández-Capetillo Ó, Tripodo C, Ferrari F, López-Contreras AJ, Costanzo V. Atashpaz S, et al. Among authors: lopez contreras aj. Elife. 2020 Mar 12;9:e54756. doi: 10.7554/eLife.54756. Elife. 2020. PMID: 32163370 Free PMC article.
DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.
Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar, Erny D, Stefanowski J, Rogell L, Klein C, Gharun K, Follo M, Seidl M, Kremer B, Münke N, Senges J, Fliegauf M, Aschman T, Pfeifer D, Sarrazin S, Sieweke MH, Wagner D, Dierks C, Haaf T, Ness T, Zaiss MM, Voll RE, Deshmukh SD, Prinz M, Goldmann T, Hölscher C, Hauser AE, Lopez-Contreras AJ, Grün D, Gorgoulis V, Diefenbach A, Henneke P, Triantafyllopoulou A. Herrtwich L, et al. Among authors: lopez contreras aj. Cell. 2018 Aug 23;174(5):1325-1326. doi: 10.1016/j.cell.2018.08.015. Cell. 2018. PMID: 30142346 Free article. No abstract available.
The mouse Gm853 gene encodes a novel enzyme: Leucine decarboxylase.
Lambertos A, Ramos-Molina B, Cerezo D, López-Contreras AJ, Peñafiel R. Lambertos A, et al. Among authors: lopez contreras aj. Biochim Biophys Acta Gen Subj. 2018 Mar;1862(3):365-376. doi: 10.1016/j.bbagen.2017.11.007. Epub 2017 Nov 4. Biochim Biophys Acta Gen Subj. 2018. PMID: 29108956
DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.
Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar, Erny D, Stefanowski J, Rogell L, Klein C, Gharun K, Follo M, Seidl M, Kremer B, Münke N, Senges J, Fliegauf M, Aschman T, Pfeifer D, Sarrazin S, Sieweke MH, Wagner D, Dierks C, Haaf T, Ness T, Zaiss MM, Voll RE, Deshmukh SD, Prinz M, Goldmann T, Hölscher C, Hauser AE, Lopez-Contreras AJ, Grün D, Gorgoulis V, Diefenbach A, Henneke P, Triantafyllopoulou A. Herrtwich L, et al. Among authors: lopez contreras aj. Cell. 2016 Nov 17;167(5):1264-1280.e18. doi: 10.1016/j.cell.2016.09.054. Epub 2016 Oct 27. Cell. 2016. PMID: 28084216 Free article.
Efficacy of ATR inhibitors as single agents in Ewing sarcoma.
Nieto-Soler M, Morgado-Palacin I, Lafarga V, Lecona E, Murga M, Callen E, Azorin D, Alonso J, Lopez-Contreras AJ, Nussenzweig A, Fernandez-Capetillo O. Nieto-Soler M, et al. Among authors: lopez contreras aj. Oncotarget. 2016 Sep 13;7(37):58759-58767. doi: 10.18632/oncotarget.11643. Oncotarget. 2016. PMID: 27577084 Free PMC article.
USP7 is a SUMO deubiquitinase essential for DNA replication.
Lecona E, Rodriguez-Acebes S, Specks J, Lopez-Contreras AJ, Ruppen I, Murga M, Muñoz J, Mendez J, Fernandez-Capetillo O. Lecona E, et al. Among authors: lopez contreras aj. Nat Struct Mol Biol. 2016 Apr;23(4):270-7. doi: 10.1038/nsmb.3185. Epub 2016 Mar 7. Nat Struct Mol Biol. 2016. PMID: 26950370 Free PMC article.
Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells.
Ruiz S, Lopez-Contreras AJ, Gabut M, Marion RM, Gutierrez-Martinez P, Bua S, Ramirez O, Olalde I, Rodrigo-Perez S, Li H, Marques-Bonet T, Serrano M, Blasco MA, Batada NN, Fernandez-Capetillo O. Ruiz S, et al. Among authors: lopez contreras aj. Nat Commun. 2015 Aug 21;6:8036. doi: 10.1038/ncomms9036. Nat Commun. 2015. PMID: 26292731 Free PMC article.
Modeling the study of DNA damage responses in mice.
Specks J, Nieto-Soler M, Lopez-Contreras AJ, Fernandez-Capetillo O. Specks J, et al. Among authors: lopez contreras aj. Methods Mol Biol. 2015;1267:413-37. doi: 10.1007/978-1-4939-2297-0_21. Methods Mol Biol. 2015. PMID: 25636482 Free PMC article. Review.
PARP-2 sustains erythropoiesis in mice by limiting replicative stress in erythroid progenitors.
Farrés J, Llacuna L, Martin-Caballero J, Martínez C, Lozano JJ, Ampurdanés C, López-Contreras AJ, Florensa L, Navarro J, Ottina E, Dantzer F, Schreiber V, Villunger A, Fernández-Capetillo O, Yélamos J. Farrés J, et al. Among authors: lopez contreras aj. Cell Death Differ. 2015 Jul;22(7):1144-57. doi: 10.1038/cdd.2014.202. Epub 2014 Dec 12. Cell Death Differ. 2015. PMID: 25501596 Free PMC article.
Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2.
Ramos-Molina B, Lambertos A, Lopez-Contreras AJ, Kasprzak JM, Czerwoniec A, Bujnicki JM, Cremades A, Peñafiel R. Ramos-Molina B, et al. Among authors: lopez contreras aj. FEBS Open Bio. 2014 Jun 2;4:510-21. doi: 10.1016/j.fob.2014.05.004. eCollection 2014. FEBS Open Bio. 2014. PMID: 24967154 Free PMC article.
INK4a/ARF limits the expansion of cells suffering from replication stress.
Monasor A, Murga M, Lopez-Contreras AJ, Navas C, Gomez G, Pisano DG, Fernandez-Capetillo O. Monasor A, et al. Among authors: lopez contreras aj. Cell Cycle. 2013 Jun 15;12(12):1948-54. doi: 10.4161/cc.25017. Epub 2013 May 15. Cell Cycle. 2013. PMID: 23676215 Free PMC article.
A proteomic characterization of factors enriched at nascent DNA molecules.
Lopez-Contreras AJ, Ruppen I, Nieto-Soler M, Murga M, Rodriguez-Acebes S, Remeseiro S, Rodrigo-Perez S, Rojas AM, Mendez J, Muñoz J, Fernandez-Capetillo O. Lopez-Contreras AJ, et al. Cell Rep. 2013 Apr 25;3(4):1105-16. doi: 10.1016/j.celrep.2013.03.009. Epub 2013 Mar 28. Cell Rep. 2013. PMID: 23545495 Free PMC article.
Cyclin-dependent kinase inhibitor p21 controls adult neural stem cell expansion by regulating Sox2 gene expression.
Marqués-Torrejón MÁ, Porlan E, Banito A, Gómez-Ibarlucea E, Lopez-Contreras AJ, Fernández-Capetillo O, Vidal A, Gil J, Torres J, Fariñas I. Marqués-Torrejón MÁ, et al. Among authors: lopez contreras aj. Cell Stem Cell. 2013 Jan 3;12(1):88-100. doi: 10.1016/j.stem.2012.12.001. Epub 2012 Dec 20. Cell Stem Cell. 2013. PMID: 23260487 Free PMC article.
BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair.
Bunting SF, Callén E, Kozak ML, Kim JM, Wong N, López-Contreras AJ, Ludwig T, Baer R, Faryabi RB, Malhowski A, Chen HT, Fernandez-Capetillo O, D'Andrea A, Nussenzweig A. Bunting SF, et al. Among authors: lopez contreras aj. Mol Cell. 2012 Apr 27;46(2):125-35. doi: 10.1016/j.molcel.2012.02.015. Epub 2012 Mar 22. Mol Cell. 2012. PMID: 22445484 Free PMC article.
Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors.
Murga M, Campaner S, Lopez-Contreras AJ, Toledo LI, Soria R, Montaña MF, Artista L, Schleker T, Guerra C, Garcia E, Barbacid M, Hidalgo M, Amati B, Fernandez-Capetillo O. Murga M, et al. Among authors: lopez contreras aj. Nat Struct Mol Biol. 2011 Nov 27;18(12):1331-1335. doi: 10.1038/nsmb.2189. Nat Struct Mol Biol. 2011. PMID: 22120667 Free PMC article.
Histone H2A C-terminus regulates chromatin dynamics, remodeling, and histone H1 binding.
Vogler C, Huber C, Waldmann T, Ettig R, Braun L, Izzo A, Daujat S, Chassignet I, Lopez-Contreras AJ, Fernandez-Capetillo O, Dundr M, Rippe K, Längst G, Schneider R. Vogler C, et al. Among authors: lopez contreras aj. PLoS Genet. 2010 Dec 9;6(12):e1001234. doi: 10.1371/journal.pgen.1001234. PLoS Genet. 2010. PMID: 21170357 Free PMC article.
The ATR barrier to replication-born DNA damage.
López-Contreras AJ, Fernandez-Capetillo O. López-Contreras AJ, et al. DNA Repair (Amst). 2010 Dec 10;9(12):1249-55. doi: 10.1016/j.dnarep.2010.09.012. Epub 2010 Oct 30. DNA Repair (Amst). 2010. PMID: 21036674 Free PMC article. Review.
Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8.
Santos MA, Huen MS, Jankovic M, Chen HT, López-Contreras AJ, Klein IA, Wong N, Barbancho JL, Fernandez-Capetillo O, Nussenzweig MC, Chen J, Nussenzweig A. Santos MA, et al. Among authors: lopez contreras aj. J Exp Med. 2010 May 10;207(5):973-81. doi: 10.1084/jem.20092308. Epub 2010 Apr 12. J Exp Med. 2010. PMID: 20385748 Free PMC article.
Sexual dimorphism of ornithine decarboxylase in the mouse adrenal: influence of polyamine deprivation on catecholamine and corticoid levels.
Bastida CM, Cremades A, Castells MT, López-Contreras AJ, López-García C, Sánchez-Mas J, Peñafiel R. Bastida CM, et al. Among authors: lopez contreras aj. Am J Physiol Endocrinol Metab. 2007 Apr;292(4):E1010-7. doi: 10.1152/ajpendo.00316.2006. Epub 2006 Dec 5. Am J Physiol Endocrinol Metab. 2007. PMID: 17148758 Free article.