Lopez-Hernandez FJ - Search Results

1

Retinoids in combination therapies for the treatment of cancer: mechanisms and perspectives.

Ortiz MA, Bayon Y, Lopez-Hernandez FJ, Piedrafita FJ. Ortiz MA, et al. Drug Resist Updat. 2002 Jul-Aug;5(3-4):162-75. doi: 10.1016/s1368-7646(02)00050-x. Drug Resist Updat. 2002. PMID: 12237083 Review.

2

The extrinsic and intrinsic apoptotic pathways are differentially affected by temperature upstream of mitochondrial damage.

López-Hernández FJ, Ortiz MA, Piedrafita FJ. López-Hernández FJ, et al. Apoptosis. 2006 Aug;11(8):1339-47. doi: 10.1007/s10495-006-7689-z. Apoptosis. 2006. PMID: 16703261

3

The retinoid antagonist MX781 induces clusterin expression in prostate cancer cells via heat shock factor-1 and activator protein-1 transcription factors.

Bayon Y, Ortiz MA, Lopez-Hernandez FJ, Howe PH, Piedrafita FJ. Bayon Y, et al. Cancer Res. 2004 Aug 15;64(16):5905-12. doi: 10.1158/0008-5472.CAN-03-3657. Cancer Res. 2004. PMID: 15313936

4

Reduced concentrations of serum enhance the antiproliferative activity of retinoid-related molecules and accelerate the onset of apoptosis.

Lopez-Hernandez FJ, Ortiz MA, Bayon Y, Piedrafita FJ. Lopez-Hernandez FJ, et al. Biochem Pharmacol. 2003 Jun 15;65(12):2021-30. doi: 10.1016/s0006-2952(03)00195-3. Biochem Pharmacol. 2003. PMID: 12787882

5

Z-FA-fmk inhibits effector caspases but not initiator caspases 8 and 10, and demonstrates that novel anticancer retinoid-related molecules induce apoptosis via the intrinsic pathway.

Lopez-Hernandez FJ, Ortiz MA, Bayon Y, Piedrafita FJ. Lopez-Hernandez FJ, et al. Mol Cancer Ther. 2003 Mar;2(3):255-63. Mol Cancer Ther. 2003. PMID: 12657720

6

Inhibition of IkappaB kinase by a new class of retinoid-related anticancer agents that induce apoptosis.

Bayon Y, Ortiz MA, Lopez-Hernandez FJ, Gao F, Karin M, Pfahl M, Piedrafita FJ. Bayon Y, et al. Mol Cell Biol. 2003 Feb;23(3):1061-74. doi: 10.1128/mcb.23.3.1061-1074.2003. Mol Cell Biol. 2003. PMID: 12529410 Free PMC article.

7

Retinoid-related molecules induce cytochrome c release and apoptosis through activation of c-Jun NH(2)-terminal kinase/p38 mitogen-activated protein kinases.

Ortiz MA, Lopez-Hernandez FJ, Bayon Y, Pfahl M, Piedrafita FJ. Ortiz MA, et al. Cancer Res. 2001 Dec 1;61(23):8504-12. Cancer Res. 2001. PMID: 11731435

8

Retinoid-related molecules require caspase 9 for the effective release of Smac and the rapid induction of apoptosis.

Lopez-Hernandez FJ, Ortiz MA, Bayon Y, Piedrafita FJ. Lopez-Hernandez FJ, et al. Cell Death Differ. 2004 Feb;11(2):154-64. doi: 10.1038/sj.cdd.4401329. Cell Death Differ. 2004. PMID: 14576769

9

Flagellin fusion proteins as adjuvants or vaccines induce specific immune responses.

Cuadros C, Lopez-Hernandez FJ, Dominguez AL, McClelland M, Lustgarten J. Cuadros C, et al. Infect Immun. 2004 May;72(5):2810-6. doi: 10.1128/iai.72.5.2810-2816.2004. Infect Immun. 2004. PMID: 15102791 Free PMC article.

10

Necrotic concentrations of cisplatin activate the apoptotic machinery but inhibit effector caspases and interfere with the execution of apoptosis.

Sancho-Martínez SM, Piedrafita FJ, Cannata-Andía JB, López-Novoa JM, López-Hernández FJ. Sancho-Martínez SM, et al. Toxicol Sci. 2011 Jul;122(1):73-85. doi: 10.1093/toxsci/kfr098. Epub 2011 Apr 28. Toxicol Sci. 2011. PMID: 21527773

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