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Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats.
Loram LC, Harrison JA, Chao L, Taylor FR, Reddy A, Travis CL, Giffard R, Al-Abed Y, Tracey K, Maier SF, Watkins LR. Loram LC, et al. Brain Behav Immun. 2010 Aug;24(6):959-67. doi: 10.1016/j.bbi.2010.03.008. Epub 2010 Mar 28. Brain Behav Immun. 2010. PMID: 20353818 Free PMC article.
Evidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activity.
Hutchinson MR, Loram LC, Zhang Y, Shridhar M, Rezvani N, Berkelhammer D, Phipps S, Foster PS, Landgraf K, Falke JJ, Rice KC, Maier SF, Yin H, Watkins LR. Hutchinson MR, et al. Among authors: loram lc. Neuroscience. 2010 Jun 30;168(2):551-63. doi: 10.1016/j.neuroscience.2010.03.067. Epub 2010 Apr 8. Neuroscience. 2010. PMID: 20381591 Free PMC article.
Opioid activation of toll-like receptor 4 contributes to drug reinforcement.
Hutchinson MR, Northcutt AL, Hiranita T, Wang X, Lewis SS, Thomas J, van Steeg K, Kopajtic TA, Loram LC, Sfregola C, Galer E, Miles NE, Bland ST, Amat J, Rozeske RR, Maslanik T, Chapman TR, Strand KA, Fleshner M, Bachtell RK, Somogyi AA, Yin H, Katz JL, Rice KC, Maier SF, Watkins LR. Hutchinson MR, et al. Among authors: loram lc. J Neurosci. 2012 Aug 15;32(33):11187-200. doi: 10.1523/JNEUROSCI.0684-12.2012. J Neurosci. 2012. PMID: 22895704 Free PMC article.
Minocycline suppresses morphine-induced respiratory depression, suppresses morphine-induced reward, and enhances systemic morphine-induced analgesia.
Hutchinson MR, Northcutt AL, Chao LW, Kearney JJ, Zhang Y, Berkelhammer DL, Loram LC, Rozeske RR, Bland ST, Maier SF, Gleeson TT, Watkins LR. Hutchinson MR, et al. Among authors: loram lc. Brain Behav Immun. 2008 Nov;22(8):1248-56. doi: 10.1016/j.bbi.2008.07.008. Epub 2008 Jul 31. Brain Behav Immun. 2008. PMID: 18706994 Free PMC article.
38 results