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The 6-aminoquinolone WC5 inhibits human cytomegalovirus replication at an early stage by interfering with the transactivating activity of viral immediate-early 2 protein.
Loregian A, Mercorelli B, Muratore G, Sinigalia E, Pagni S, Massari S, Gribaudo G, Gatto B, Palumbo M, Tabarrini O, Cecchetti V, Palù G. Loregian A, et al. Antimicrob Agents Chemother. 2010 May;54(5):1930-40. doi: 10.1128/AAC.01730-09. Epub 2010 Mar 1. Antimicrob Agents Chemother. 2010. PMID: 20194695 Free PMC article.
Drug Repurposing for Viral Infectious Diseases: How Far Are We?
Mercorelli B, Palù G, Loregian A. Mercorelli B, et al. Among authors: loregian a. Trends Microbiol. 2018 Oct;26(10):865-876. doi: 10.1016/j.tim.2018.04.004. Epub 2018 May 11. Trends Microbiol. 2018. PMID: 29759926 Free PMC article. Review.
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