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2023 7
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Page 1
Advancing biological understanding of cellular senescence with computational multiomics.
Li S, Agudelo Garcia PA, Aliferis C, Becich MJ, Calyeca J, Cosgrove BD, Elisseeff J, Farzad N, Fertig EJ, Glass C, Gu L, Hu Q, Ji Z, Königshoff M, LeBrasseur NK, Li D, Ma A, Ma Q, Menon V, Mitchell JT, Mora AL, Nagaraj S, Nelson AC, Niedernhofer LJ, Rojas M, Taha HB, Wang J, Wang S, Wu PH, Xie J, Xu M, Yu M, Zhang X, Zhao Y, Adams PD, Aguayo-Mazzucato C, Baker DJ, Benz C, Bernlohr DA, Bueno M, Chen J, Childs BG, Chuang JH, Chung D, Dileepan M, Ding L, Dong M, Duncan F, Enninful A, Flynn WF, Franco AC, Furman D, Garovic V, Halene S, Herman AB, Hertzel AV, Iwasaki K, Jeon H, Kang JW, Karmakar S, Kirkland JL, Korstanje R, Kummerfeld E, Lee JH, Liu Y, Lu Y, Lugo-Martinez J, Martini H, Melov S, Musi N, Passos JF, Peters ST, Rahman I, Ramasamy R, Rindone AN, Robbins PD, Robson P, Rodriguez-Lopez J, Rosas L, Rosenthal N, Schafer MJ, Schilling B, Schmidt EL, Schneider K, Sengupta K, Shu J, So PTC, Sun L, Tchkonia T, Teneche MG, Vanegas N, Wang J, Xie J, Yin S, Zhang K, Zhu Q, Fan R; SenNet Consortium. Li S, et al. Among authors: rosas l. Nat Genet. 2025 Oct;57(10):2381-2394. doi: 10.1038/s41588-025-02314-y. Epub 2025 Sep 15. Nat Genet. 2025. PMID: 40954249 Free PMC article. Review.
RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension.
Piper B, Bogamuwa S, Hossain T, Farkas D, Rosas L, Green AC, Newcomb G, Sun N, Ovando-Ricardez JA, Horowitz JC, Bhagwani AR, Yang H, Kudryashova TV, Rojas M, Mora AL, Yan P, Mallampalli RK, Goncharova EA, Eckmann DM, Farkas L. Piper B, et al. Among authors: rosas l. J Clin Invest. 2024 Feb 1;134(3):e169441. doi: 10.1172/JCI169441. J Clin Invest. 2024. PMID: 38015641 Free PMC article.
BIK polymorphism and proteasome regulation unveil host risk factor for severe influenza.
Soni S, Yildiz S, Allen EK, Petersen H, Peeples M, El Zahed S, Rosas L, Anang V, Antonescu L, Nho RS, Mora AL, Horowitz JC, Rojas M, Medina RA, Thomas PG, García-Sastre A, Tesfaigzi Y, Mebratu YA. Soni S, et al. Among authors: rosas l. Proc Natl Acad Sci U S A. 2025 Jul 15;122(28):e2424367122. doi: 10.1073/pnas.2424367122. Epub 2025 Jul 8. Proc Natl Acad Sci U S A. 2025. PMID: 40627391 Free PMC article.
Targeted degradation of extracellular mitochondrial aspartyl-tRNA synthetase modulates immune responses.
Johnson BS, Farkas D, El-Mergawy R, Adair JA, Elhance A, Eltobgy M, Coan FM, Chafin L, Joseph JA, Cornwell A, Johns FJ, Rosas L, Rojas M, Farkas L, Bednash JS, Londino JD, Ray P, Ray A, Kagan V, Lee JS, Chen BB, Mallampalli RK. Johnson BS, et al. Among authors: rosas l. Nat Commun. 2024 Jul 22;15(1):6172. doi: 10.1038/s41467-024-50031-7. Nat Commun. 2024. PMID: 39039092 Free PMC article.
LEF1 isoforms regulate cellular senescence and aging.
Jia M, Sayed K, Kapetanaki MG, Dion W, Rosas L, Irfan S, Valenzi E, Mora AL, Lafyatis RA, Rojas M, Zhu B, Benos PV. Jia M, et al. Among authors: rosas l. Aging Cell. 2023 Dec;22(12):e14024. doi: 10.1111/acel.14024. Epub 2023 Nov 13. Aging Cell. 2023. PMID: 37961030 Free PMC article.
An Intrinsic-hoc Framework for Heterogeneous Cellular Senescence Elucidation Using Deep Graph Representation Learning and Experimental Validation.
Ma A, Cheng H, Vanegas NDP, Ghobashi A, Chen H, Rodriguez J, Rosas L, Wang C, Shao J, Jiang Y, Wang X, Rahman I, Lugo-Martinez J, Li D, Pryhuber GS, Bar-Joseph Z, Eickelberg O, Königshoff M, Chung D, Chen R, Finkel T, Mora A, Rojas M, Ma Q. Ma A, et al. Among authors: rosas l. bioRxiv [Preprint]. 2025 Jul 4:2025.07.01.662364. doi: 10.1101/2025.07.01.662364. bioRxiv. 2025. PMID: 40631080 Free PMC article. Preprint.
23 results