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Upd3--an ancestor of the four-helix bundle cytokines.
Oldefest M, Nowinski J, Hung CW, Neelsen D, Trad A, Tholey A, Grötzinger J, Lorenzen I. Oldefest M, et al. Among authors: lorenzen i. Biochem Biophys Res Commun. 2013 Jun 21;436(1):66-72. doi: 10.1016/j.bbrc.2013.04.107. Epub 2013 May 22. Biochem Biophys Res Commun. 2013. PMID: 23707937
Structure and function of a unique pore-forming protein from a pathogenic acanthamoeba.
Michalek M, Sönnichsen FD, Wechselberger R, Dingley AJ, Hung CW, Kopp A, Wienk H, Simanski M, Herbst R, Lorenzen I, Marciano-Cabral F, Gelhaus C, Gutsmann T, Tholey A, Grötzinger J, Leippe M. Michalek M, et al. Among authors: lorenzen i. Nat Chem Biol. 2013 Jan;9(1):37-42. doi: 10.1038/nchembio.1116. Epub 2012 Nov 11. Nat Chem Biol. 2013. PMID: 23143413
Secreted Frizzled-related protein 3 (sFRP3)-mediated suppression of interleukin-6 receptor release by A disintegrin and metalloprotease 17 (ADAM17) is abrogated in the osteoarthritis-associated rare double variant of sFRP3.
Oldefest M, Düsterhöft S, Desel C, Thysen S, Fink C, Rabe B, Lories R, Grötzinger J, Lorenzen I. Oldefest M, et al. Among authors: lorenzen i. Biochem J. 2015 Jun 15;468(3):507-18. doi: 10.1042/BJ20141231. Epub 2015 Apr 7. Biochem J. 2015. PMID: 25846075
Distance dependent shedding of IL-6R.
Düsterhöft S, Bartels AK, Koudelka T, Lilienthal E, Schäfer M, Garbers C, Tholey A, Grötzinger J, Lorenzen I. Düsterhöft S, et al. Among authors: lorenzen i. Biochem Biophys Res Commun. 2020 May 28;526(2):355-360. doi: 10.1016/j.bbrc.2020.03.093. Epub 2020 Mar 26. Biochem Biophys Res Commun. 2020. PMID: 32222277
229 results