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MYC-induced human acute myeloid leukemia requires a continuing IL-3/GM-CSF costimulus.
Bulaeva E, Pellacani D, Nakamichi N, Hammond CA, Beer PA, Lorzadeh A, Moksa M, Carles A, Bilenky M, Lefort S, Shu J, Wilhelm BT, Weng AP, Hirst M, Eaves CJ. Bulaeva E, et al. Among authors: lorzadeh a. Blood. 2020 Dec 10;136(24):2764-2773. doi: 10.1182/blood.2020006374. Blood. 2020. PMID: 33301029 Free article.
Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity.
Giambra V, Gusscott S, Gracias D, Song R, Lam SH, Panelli P, Tyshchenko K, Jenkins CE, Hoofd C, Lorzadeh A, Carles A, Hirst M, Eaves CJ, Weng AP. Giambra V, et al. Among authors: lorzadeh a. Cell Stem Cell. 2018 Nov 1;23(5):714-726.e7. doi: 10.1016/j.stem.2018.08.018. Epub 2018 Sep 27. Cell Stem Cell. 2018. PMID: 30269902 Free article.
[No title available]
[No authors listed] [No authors listed] PMID: 32599616
Regulatory variation: an emerging vantage point for cancer biology.
Li L, Lorzadeh A, Hirst M. Li L, et al. Among authors: lorzadeh a. Wiley Interdiscip Rev Syst Biol Med. 2014 Jan-Feb;6(1):37-59. doi: 10.1002/wsbm.1250. Epub 2013 Nov 19. Wiley Interdiscip Rev Syst Biol Med. 2014. PMID: 24254976 Review.
Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia.
Kusakabe M, Sun AC, Tyshchenko K, Wong R, Nanda A, Shanna C, Gusscott S, Chavez EA, Lorzadeh A, Zhu A, Hill A, Hung S, Brown S, Babaian A, Wang X, Holt RA, Steidl C, Karsan A, Humphries RK, Eaves CJ, Hirst M, Weng AP. Kusakabe M, et al. Among authors: lorzadeh a. Nat Commun. 2019 Jul 2;10(1):2913. doi: 10.1038/s41467-019-10510-8. Nat Commun. 2019. PMID: 31266935 Free PMC article.
MicroRNA-708 is a novel regulator of the Hoxa9 program in myeloid cells.
Schneider E, Pochert N, Ruess C, MacPhee L, Escano L, Miller C, Krowiorz K, Delsing Malmberg E, Heravi-Moussavi A, Lorzadeh A, Ashouri A, Grasedieck S, Sperb N, Kumar Kopparapu P, Iben S, Staffas A, Xiang P, Rösler R, Kanduri M, Larsson E, Fogelstrand L, Döhner H, Döhner K, Wiese S, Hirst M, Keith Humphries R, Palmqvist L, Kuchenbauer F, Rouhi A. Schneider E, et al. Among authors: lorzadeh a. Leukemia. 2020 May;34(5):1253-1265. doi: 10.1038/s41375-019-0651-1. Epub 2019 Nov 25. Leukemia. 2020. PMID: 31768018
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