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SOCS-1 localizes to the microtubule organizing complex-associated 20S proteasome.
Vuong BQ, Arenzana TL, Showalter BM, Losman J, Chen XP, Mostecki J, Banks AS, Limnander A, Fernandez N, Rothman PB. Vuong BQ, et al. Among authors: losman j. Mol Cell Biol. 2004 Oct;24(20):9092-101. doi: 10.1128/MCB.24.20.9092-9101.2004. Mol Cell Biol. 2004. PMID: 15456882 Free PMC article.
TRIM8/GERP RING finger protein interacts with SOCS-1.
Toniato E, Chen XP, Losman J, Flati V, Donahue L, Rothman P. Toniato E, et al. Among authors: losman j. J Biol Chem. 2002 Oct 4;277(40):37315-22. doi: 10.1074/jbc.M205900200. Epub 2002 Aug 5. J Biol Chem. 2002. PMID: 12163497 Free article.
Pim serine/threonine kinases regulate the stability of Socs-1 protein.
Chen XP, Losman JA, Cowan S, Donahue E, Fay S, Vuong BQ, Nawijn MC, Capece D, Cohan VL, Rothman P. Chen XP, et al. Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2175-80. doi: 10.1073/pnas.042035699. Proc Natl Acad Sci U S A. 2002. PMID: 11854514 Free PMC article.
SOCS proteins, regulators of intracellular signaling.
Chen XP, Losman JA, Rothman P. Chen XP, et al. Among authors: losman ja. Immunity. 2000 Sep;13(3):287-90. doi: 10.1016/s1074-7613(00)00028-5. Immunity. 2000. PMID: 11021526 Free article. Review. No abstract available.
D-2-hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice.
Akbay EA, Moslehi J, Christensen CL, Saha S, Tchaicha JH, Ramkissoon SH, Stewart KM, Carretero J, Kikuchi E, Zhang H, Cohoon TJ, Murray S, Liu W, Uno K, Fisch S, Jones K, Gurumurthy S, Gliser C, Choe S, Keenan M, Son J, Stanley I, Losman JA, Padera R, Bronson RT, Asara JM, Abdel-Wahab O, Amrein PC, Fathi AT, Danial NN, Kimmelman AC, Kung AL, Ligon KL, Yen KE, Kaelin WG Jr, Bardeesy N, Wong KK. Akbay EA, et al. Among authors: losman ja. Genes Dev. 2014 Mar 1;28(5):479-90. doi: 10.1101/gad.231233.113. Genes Dev. 2014. PMID: 24589777 Free PMC article.
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation.
Koivunen P, Lee S, Duncan CG, Lopez G, Lu G, Ramkissoon S, Losman JA, Joensuu P, Bergmann U, Gross S, Travins J, Weiss S, Looper R, Ligon KL, Verhaak RG, Yan H, Kaelin WG Jr. Koivunen P, et al. Among authors: losman ja. Nature. 2012 Feb 15;483(7390):484-8. doi: 10.1038/nature10898. Nature. 2012. PMID: 22343896 Free PMC article.
61 results