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Loss of mammalian Sprouty2 leads to enteric neuronal hyperplasia and esophageal achalasia.
Taketomi T, Yoshiga D, Taniguchi K, Kobayashi T, Nonami A, Kato R, Sasaki M, Sasaki A, Ishibashi H, Moriyama M, Nakamura K, Nishimura J, Yoshimura A. Taketomi T, et al. Nat Neurosci. 2005 Jul;8(7):855-7. doi: 10.1038/nn1485. Nat Neurosci. 2005. PMID: 15937482
We report here that loss of the Sprouty2 gene (also known as Spry2) in mice resulted in enteric nerve hyperplasia, which led to esophageal achalasia and intestinal pseudo-obstruction. Glial cell line-derived neurotrophic factor (GDNF) ind …
We report here that loss of the Sprouty2 gene (also known as Spry2) in mice resulted in enteric nerve hyperplasia …
Esophageal motor disorders: recent advances.
Dogan I, Mittal RK. Dogan I, et al. Curr Opin Gastroenterol. 2006 Jul;22(4):417-22. doi: 10.1097/01.mog.0000231818.64138.8a. Curr Opin Gastroenterol. 2006. PMID: 16760760 Review.
Several studies address the function of longitudinal muscle layer of the esophagus in normal subjects and patients with motor disorders of the esophagus. Esophageal electrical impedance recordings reveal abnormal transit in patients with diffuse esophageal spasm, …
Several studies address the function of longitudinal muscle layer of the esophagus in normal subjects and patients with motor disorders of t …