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Page 1
Showing results for loss of adipose fatty acid oxidation does not potentiate obesity at thermonuetrality. Cell Rep. 14(6):1308-16
Your search for Loss of Adipose Fatty Acid Oxidation Does Not Potentiate Obesity at Thermoneutrality. Cell Rep. 14(6):1308-16 retrieved no results
Understanding the Physiology of FGF21.
Fisher FM, Maratos-Flier E. Fisher FM, et al. Annu Rev Physiol. 2016;78:223-41. doi: 10.1146/annurev-physiol-021115-105339. Epub 2015 Nov 19. Annu Rev Physiol. 2016. PMID: 26654352 Review.
In the liver, FGF21 plays an important role in the regulation of fatty acid oxidation both in the fasted state and in mice consuming a high-fat, low-carbohydrate ketogenic diet. FGF21 also regulates fatty acid metabolism in mice consuming a diet …
In the liver, FGF21 plays an important role in the regulation of fatty acid oxidation both in the fasted state and in m …
Adipose Tissue Dysfunction in Polycystic Ovary Syndrome.
Bril F, Ezeh U, Amiri M, Hatoum S, Pace L, Chen YH, Bertrand F, Gower B, Azziz R. Bril F, et al. J Clin Endocrinol Metab. 2023 Dec 21;109(1):10-24. doi: 10.1210/clinem/dgad356. J Clin Endocrinol Metab. 2023. PMID: 37329216 Free PMC article.
PURPOSE: Polycystic ovary syndrome (PCOS) is a complex genetic trait and the most common endocrine disorder of women, clinically evident in 5% to 15% of reproductive-aged women globally, with associated cardiometabolic dysfunction. Adipose tissue (AT) dysfunction appears t …
PURPOSE: Polycystic ovary syndrome (PCOS) is a complex genetic trait and the most common endocrine disorder of women, clinically evident in …
Energy Metabolism Changes and Dysregulated Lipid Metabolism in Postmenopausal Women.
Ko SH, Jung Y. Ko SH, et al. Nutrients. 2021 Dec 20;13(12):4556. doi: 10.3390/nu13124556. Nutrients. 2021. PMID: 34960109 Free PMC article. Review.
In particular, increased bone marrow-derived adipocytes due to estrogen loss contribute to increased visceral fat in postmenopausal women. Enhanced visceral fat lipolysis by adipose tissue lipoprotein lipase triggers the production of excessive free fatty …
In particular, increased bone marrow-derived adipocytes due to estrogen loss contribute to increased visceral fat in postmenopausal w …
Effects of intermittent fasting on glucose and lipid metabolism.
Antoni R, Johnston KL, Collins AL, Robertson MD. Antoni R, et al. Proc Nutr Soc. 2017 Aug;76(3):361-368. doi: 10.1017/S0029665116002986. Epub 2017 Jan 16. Proc Nutr Soc. 2017. PMID: 28091348 Review.
There is some suggestion that the metabolic changes elicited by these approaches can occur in the absence of energy restriction, and in the context of IER, may be distinct from those observed following similar weight-loss achieved via modest continuous energy restriction. …
There is some suggestion that the metabolic changes elicited by these approaches can occur in the absence of energy restriction, and in the …
Lipid metabolism in MASLD and MASH: From mechanism to the clinic.
Carli F, Della Pepa G, Sabatini S, Vidal Puig A, Gastaldelli A. Carli F, et al. JHEP Rep. 2024 Aug 9;6(12):101185. doi: 10.1016/j.jhepr.2024.101185. eCollection 2024 Dec. JHEP Rep. 2024. PMID: 39583092 Free PMC article. Review.
Metabolic dysfunction-associated steatotic liver disease/steatohepatitis (MASLD/MASH) is recognised as a metabolic disease characterised by excess intrahepatic lipid accumulation due to lipid overflow and synthesis, alongside impaired oxidation and/or export of these lipid …
Metabolic dysfunction-associated steatotic liver disease/steatohepatitis (MASLD/MASH) is recognised as a metabolic disease characterised by …
Exogenous Ketone Supplements in Athletic Contexts: Past, Present, and Future.
Evans M, McClure TS, Koutnik AP, Egan B. Evans M, et al. Sports Med. 2022 Dec;52(Suppl 1):25-67. doi: 10.1007/s40279-022-01756-2. Epub 2022 Oct 10. Sports Med. 2022. PMID: 36214993 Free PMC article. Review.
The ketone bodies acetoacetate (AcAc) and beta-hydroxybutyrate (betaHB) have pleiotropic effects in multiple organs including brain, heart, and skeletal muscle by serving as an alternative substrate for energy provision, and by modulating inflammation, oxidative stress, ca …
The ketone bodies acetoacetate (AcAc) and beta-hydroxybutyrate (betaHB) have pleiotropic effects in multiple organs including brain, heart, …
Scientific Challenges on Theory of Fat Burning by Exercise.
Harris MB, Kuo CH. Harris MB, et al. Front Physiol. 2021 Jul 6;12:685166. doi: 10.3389/fphys.2021.685166. eCollection 2021. Front Physiol. 2021. PMID: 34295263 Free PMC article.
Nevertheless, increasing exercise intensity decreases oxidation of fatty acids derived from adipose tissue despite elevated lipolysis. The unchanged 24-h fatty acid oxidation during and after exercise does not provide support to th …
Nevertheless, increasing exercise intensity decreases oxidation of fatty acids derived from adipose tissue despi …
Targeting activin receptor-like kinase 7 ameliorates adiposity and associated metabolic disorders.
Zhao M, Okunishi K, Bu Y, Kikuchi O, Wang H, Kitamura T, Izumi T. Zhao M, et al. JCI Insight. 2023 Feb 22;8(4):e161229. doi: 10.1172/jci.insight.161229. JCI Insight. 2023. PMID: 36626233 Free PMC article.
In the present study, treatment with a neutralizing mAb against ALK7 caused a substantial loss of adipose mass and improved glucose intolerance and insulin resistance in both genetic and diet-induced mouse obesity models. The enhanced lipolysis increased f …
In the present study, treatment with a neutralizing mAb against ALK7 caused a substantial loss of adipose mass and improved gl …
Lipid Toxicity in the Cardiovascular-Kidney-Metabolic Syndrome (CKMS).
D'Elia JA, Weinrauch LA. D'Elia JA, et al. Biomedicines. 2024 Apr 29;12(5):978. doi: 10.3390/biomedicines12050978. Biomedicines. 2024. PMID: 38790940 Free PMC article. Review.
Cardiac energy for ventricular contraction/relaxation is preferentially supplied by long chain fatty acids. Metabolism of long chain fatty acids is accomplished within the cardiomyocyte cytoplasm and mitochondria by means of the glycolytic, tricarboxyl …
Cardiac energy for ventricular contraction/relaxation is preferentially supplied by long chain fatty acids. Metabolism of long …
Dynamic metabolism of endothelial triglycerides protects against atherosclerosis in mice.
Boutagy NE, Gamez-Mendez A, Fowler JW, Zhang H, Chaube BK, Esplugues E, Kuo A, Lee S, Horikami D, Zhang J, Citrin KM, Singh AK, Coon BG, Lee MY, Suarez Y, Fernandez-Hernando C, Sessa WC. Boutagy NE, et al. J Clin Invest. 2024 Jan 4;134(4):e170453. doi: 10.1172/JCI170453. J Clin Invest. 2024. PMID: 38175710 Free PMC article.
How large blood vessels, the site of atherosclerotic vascular disease, regulate the flux of fatty acids (FAs) into triglyceride-rich (TG-rich) lipid droplets (LDs) is not known. In this study, we showed that deletion of the enzyme adipose TG lipase (ATGL) in …
How large blood vessels, the site of atherosclerotic vascular disease, regulate the flux of fatty acids (FAs) into triglycerid …
584 results