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An open-label extension study to investigate the long-term safety and tolerability of THC/CBD oromucosal spray and oromucosal THC spray in patients with terminal cancer-related pain refractory to strong opioid analgesics.
Johnson JR, Lossignol D, Burnell-Nugent M, Fallon MT. Johnson JR, et al. J Pain Symptom Manage. 2013 Aug;46(2):207-18. doi: 10.1016/j.jpainsymman.2012.07.014. Epub 2012 Nov 8. J Pain Symptom Manage. 2013. PMID: 23141881 Clinical Trial.
Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain.
Johnson JR, Burnell-Nugent M, Lossignol D, Ganae-Motan ED, Potts R, Fallon MT. Johnson JR, et al. J Pain Symptom Manage. 2010 Feb;39(2):167-79. doi: 10.1016/j.jpainsymman.2009.06.008. Epub 2009 Nov 5. J Pain Symptom Manage. 2010. PMID: 19896326 Clinical Trial.
Longitudinal follow-up of TTS-fentanyl use in patients with cancer-related pain: results of a compassionate-use study with special focus on elderly patients.
Menten J, Desmedt M, Lossignol D, Mullie A. Menten J, et al. Curr Med Res Opin. 2002;18(8):488-98. doi: 10.1185/030079902125001272. Curr Med Res Opin. 2002. PMID: 12564660
Psychological interventions to reduce pain in patients with cancer.
Lossignol DA. Lossignol DA. Curr Opin Oncol. 2013 Jul;25(4):368-72. doi: 10.1097/CCO.0b013e3283621090. Curr Opin Oncol. 2013. PMID: 23736877 Review.
Pitfalls in the use of opiates in treatment of cancer pain.
Lossignol DA. Lossignol DA. Support Care Cancer. 1993 Sep;1(5):256-8. doi: 10.1007/BF00366045. Support Care Cancer. 1993. PMID: 8156236
Successful use of ketamine for intractable cancer pain.
Lossignol DA, Obiols-Portis M, Body JJ. Lossignol DA, et al. Support Care Cancer. 2005 Mar;13(3):188-93. doi: 10.1007/s00520-004-0684-4. Epub 2004 Oct 6. Support Care Cancer. 2005. PMID: 15480820
The emergence of intractable pain may notably be due to the activation of N-methyl-D-aspartate (NMDA) receptors located in the central nervous system. ...
The emergence of intractable pain may notably be due to the activation of N-methyl-D-aspartate (NMDA) receptors located in the centra …
[Pain and cancer].
Lossignol DA. Lossignol DA. Rev Med Brux. 1991 Jun;12(6):215-21. Rev Med Brux. 1991. PMID: 1866508 Review. French.
Cannabinoids: a new approach for pain control?
Lossignol D. Lossignol D. Curr Opin Oncol. 2019 Jul;31(4):275-279. doi: 10.1097/CCO.0000000000000523. Curr Opin Oncol. 2019. PMID: 30789867 Review.
The concept of rehabilitation of cancer patients.
Body JJ, Lossignol D, Ronson A. Body JJ, et al. Curr Opin Oncol. 1997 Jul;9(4):332-40. doi: 10.1097/00001622-199709040-00005. Curr Opin Oncol. 1997. PMID: 9251883 Review.
[Transdermal fentanyl].
Lossignol D, Sternon J. Lossignol D, et al. Rev Med Brux. 1998 Apr;19(2):83-6. Rev Med Brux. 1998. PMID: 9643088 Review. French.
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