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A panel of intestinal differentiation markers (CDX2, GPA33, and LI-cadherin) identifies gastric cancer patients with favourable prognosis.
Lopes N, Bergsland C, Bruun J, Bjørnslett M, Vieira AF, Mesquita P, Pinto R, Gomes R, Cavadas B, Bennett E, Pereira L, Lothe RA, Almeida R, David L. Lopes N, et al. Among authors: Lothe RA. Gastric Cancer. 2020 Mar 25. doi: 10.1007/s10120-020-01064-6. Online ahead of print. Gastric Cancer. 2020. PMID: 32215766
Patient-derived organoids from multiple colorectal cancer liver metastases reveal moderate intra-patient pharmacotranscriptomic heterogeneity.
Bruun J, Kryeziu K, Eide PW, Moosavi SH, Eilertsen IA, Langerud J, Røsok BI, Totland MZ, Brunsell TH, Pellinen T, Saarela J, Bergsland CH, Palmer HG, Brudvik KW, Guren T, Dienstmann R, Guren MG, Nesbakken A, Bjørnbeth BA, Sveen A, Lothe RA. Bruun J, et al. Among authors: Lothe RA. Clin Cancer Res. 2020 Apr 16:clincanres.3637.2019. doi: 10.1158/1078-0432.CCR-19-3637. Online ahead of print. Clin Cancer Res. 2020. PMID: 32299813 Free article.
Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series.
Wise JF, Nakken S, Steen CB, Vodák D, Trøen G, Johannessen B, Lingjærde OC, Hilden V, Blaker YN, Bai B, Aasheim LB, Pasanen A, Lorenz S, Sveen A, Lothe RA, Myklebost O, Leppä S, Meza-Zepeda LA, Beiske K, Lawrence MS, Hovig E, Myklebust JH, Smeland EB, Holte H. Wise JF, et al. Among authors: Lothe RA. Blood Adv. 2020 May 12;4(9):1859-1866. doi: 10.1182/bloodadvances.2019001325. Blood Adv. 2020. PMID: 32374878 Free PMC article.
Improved prognostication of glioblastoma beyond molecular subtyping by transcriptional profiling of the tumor microenvironment.
Jeanmougin M, Håvik AB, Cekaite L, Brandal P, Sveen A, Meling TR, Ågesen TH, Scheie D, Heim S, Lothe RA, Lind GE. Jeanmougin M, et al. Among authors: Lothe RA. Mol Oncol. 2020 May;14(5):1016-1027. doi: 10.1002/1878-0261.12668. Epub 2020 Apr 4. Mol Oncol. 2020. PMID: 32171051 Free PMC article.
High Concordance and Negative Prognostic Impact of RAS/BRAF/PIK3CA Mutations in Multiple Resected Colorectal Liver Metastases.
Brunsell TH, Sveen A, Bjørnbeth BA, Røsok BI, Danielsen SA, Brudvik KW, Berg KCG, Johannessen B, Cengija V, Abildgaard A, Guren MG, Nesbakken A, Lothe RA. Brunsell TH, et al. Among authors: Lothe RA. Clin Colorectal Cancer. 2020 Mar;19(1):e26-e47. doi: 10.1016/j.clcc.2019.09.003. Epub 2019 Dec 12. Clin Colorectal Cancer. 2020. PMID: 31982351 Free article.
Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon.
Burocziova M, Burdova K, Martinikova AS, Kasparek P, Kleiblova P, Danielsen SA, Borecka M, Jenikova G, Janečková L, Pavel J, Zemankova P, Schneiderova M, Schwarzova L, Ticha I, Sun XF, Jiraskova K, Liska V, Vodickova L, Vodicka P, Sedlacek R, Kleibl Z, Lothe RA, Korinek V, Macurek L. Burocziova M, et al. Among authors: Lothe RA. Cell Death Dis. 2019 Oct 28;10(11):818. doi: 10.1038/s41419-019-2057-4. Cell Death Dis. 2019. PMID: 31659152 Free PMC article.
Digital image analysis of multiplex fluorescence IHC in colorectal cancer recognizes the prognostic value of CDX2 and its negative correlation with SOX2.
Lopes N, Bergsland CH, Bjørnslett M, Pellinen T, Svindland A, Nesbakken A, Almeida R, Lothe RA, David L, Bruun J. Lopes N, et al. Among authors: Lothe RA. Lab Invest. 2020 Jan;100(1):120-134. doi: 10.1038/s41374-019-0336-4. Epub 2019 Oct 22. Lab Invest. 2020. PMID: 31641225 Free PMC article.
Correction: Tumour-infiltrating CD8+ lymphocytes and colorectal cancer recurrence by tumour and nodal stage.
Glaire MA, Domingo E, Sveen A, Bruun J, Nesbakken A, Nicholson G, Novelli M, Lawson K, Oukrif D, Kildal W, Danielsen HE, Kerr R, Kerr D, Tomlinson I, Lothe RA, Church DN. Glaire MA, et al. Among authors: Lothe RA. Br J Cancer. 2019 Oct;121(9):807. doi: 10.1038/s41416-019-0590-7. Br J Cancer. 2019. PMID: 31548598 Free PMC article.
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