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Large granular lymphocyte leukemia and pre-capillary pulmonary hypertension.
Cherel B, Humbert M, LeBlanc F, Zambello R, Hamidou M, Lifermann F, Montani D, Leoncin M, Decaux O, Pastoret C, Le Bourgeois A, Dominique S, Chabanne C, Loughran TP Jr, Lamy T. Cherel B, et al. Among authors: loughran tp jr. Chest. 2020 Sep 10:S0012-3692(20)34353-1. doi: 10.1016/j.chest.2020.07.094. Online ahead of print. Chest. 2020. PMID: 32919988 No abstract available.
Large granular lymphocyte leukemia serum and corresponding hematological parameters reveal unique cytokine and sphingolipid biomarkers and associations with STAT3 mutations.
Olson KC, Moosic KB, Jones MK, Larkin PMK, Olson TL, Toro MF, Fox TE, Feith DJ, Loughran TP Jr. Olson KC, et al. Among authors: loughran tp jr. Cancer Med. 2020 Jul 25;9(18):6533-49. doi: 10.1002/cam4.3246. Online ahead of print. Cancer Med. 2020. PMID: 32710512 Free PMC article.
The PI3K/AKT Pathway Inhibitor ISC-4 Induces Apoptosis and Inhibits Growth of Leukemia in Preclinical Models of Acute Myeloid Leukemia.
Annageldiyev C, Tan SF, Thakur S, Dhanyamraju PK, Ramisetti SR, Bhadauria P, Schick J, Zeng Z, Sharma V, Dunton W, Dovat S, Desai D, Zheng H, Feith DJ, Loughran TP Jr, Amin S, Sharma AK, Claxton D, Sharma A. Annageldiyev C, et al. Among authors: loughran tp jr. Front Oncol. 2020 Apr 1;10:393. doi: 10.3389/fonc.2020.00393. eCollection 2020. Front Oncol. 2020. PMID: 32296637 Free PMC article.
Sphingosine kinase-2 is overexpressed in large granular lymphocyte leukaemia and promotes survival through Mcl-1.
LeBlanc FR, Pearson JM, Tan SF, Cheon H, Xing JC, Dunton W, Feith DJ, Loughran TP Jr. LeBlanc FR, et al. Among authors: loughran tp jr. Br J Haematol. 2020 Aug;190(3):405-417. doi: 10.1111/bjh.16530. Epub 2020 Mar 2. Br J Haematol. 2020. PMID: 32124438
Advances in the Diagnosis and Treatment of Large Granular Lymphocytic Leukemia.
Cheon H, Dziewulska KH, Moosic KB, Olson KC, Gru AA, Feith DJ, Loughran TP Jr. Cheon H, et al. Among authors: loughran tp jr. Curr Hematol Malig Rep. 2020 Apr;15(2):103-112. doi: 10.1007/s11899-020-00565-6. Curr Hematol Malig Rep. 2020. PMID: 32062772 Review.
Whole Genome Sequencing of Spontaneously Occurring Rat Natural Killer Large Granular Lymphocyte Leukemia Identifies JAK1 Somatic Activating Mutation.
Wang TT, Yang J, Dighe S, Schmachtenberg MW, Leigh NT, Farber E, Onengut-Gumuscu S, Feith DJ, Ratan A, Loughran TP Jr, Olson TL. Wang TT, et al. Among authors: loughran tp jr. Cancers (Basel). 2020 Jan 3;12(1):126. doi: 10.3390/cancers12010126. Cancers (Basel). 2020. PMID: 31947841 Free PMC article.
Retroviral sero-reactivity in LGL leukaemia patients and family members.
Nyland SB, Feith DJ, Poss M, Olson TL, Krissinger DJ, Poiesz BJ, Ruscetti FW, Loughran TP Jr. Nyland SB, et al. Among authors: loughran tp jr. Br J Haematol. 2020 Feb;188(4):522-527. doi: 10.1111/bjh.16223. Epub 2019 Oct 14. Br J Haematol. 2020. PMID: 31608437 Clinical Trial.
Genomics of LGL leukemia and select other rare leukemia/lymphomas.
Moosic KB, Paila U, Olson KC, Dziewulska K, Wang TT, Xing JC, Ratan A, Feith DJ, Loughran TP Jr, Olson TL. Moosic KB, et al. Among authors: loughran tp jr. Best Pract Res Clin Haematol. 2019 Sep;32(3):196-206. doi: 10.1016/j.beha.2019.06.003. Epub 2019 Jun 6. Best Pract Res Clin Haematol. 2019. PMID: 31585620 Free PMC article. Review.
Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia.
Barth BM, Wang W, Toran PT, Fox TE, Annageldiyev C, Ondrasik RM, Keasey NR, Brown TJ, Devine VG, Sullivan EC, Cote AL, Papakotsi V, Tan SF, Shanmugavelandy SS, Deering TG, Needle DB, Stern ST, Zhu J, Liao J, Viny AD, Feith DJ, Levine RL, Wang HG, Loughran TP Jr, Sharma A, Kester M, Claxton DF. Barth BM, et al. Among authors: loughran tp jr. Blood Adv. 2019 Sep 10;3(17):2598-2603. doi: 10.1182/bloodadvances.2018021295. Blood Adv. 2019. PMID: 31488436 Free PMC article.
Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells.
Kao LP, Morad SAF, Davis TS, MacDougall MR, Kassai M, Abdelmageed N, Fox TE, Kester M, Loughran TP Jr, Abad JL, Fabrias G, Tan SF, Feith DJ, Claxton DF, Spiegel S, Fisher-Wellman KH, Cabot MC. Kao LP, et al. Among authors: loughran tp jr. J Lipid Res. 2019 Sep;60(9):1590-1602. doi: 10.1194/jlr.RA119000251. Epub 2019 Jul 30. J Lipid Res. 2019. PMID: 31363040 Free PMC article.
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