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Machine learning based CRISPR gRNA design for therapeutic exon skipping.
Louie W, Shen MW, Tahiry Z, Zhang S, Worstell D, Cassa CA, Sherwood RI, Gifford DK. Louie W, et al. PLoS Comput Biol. 2021 Jan 8;17(1):e1008605. doi: 10.1371/journal.pcbi.1008605. eCollection 2021 Jan. PLoS Comput Biol. 2021. PMID: 33417623 Free PMC article.
Monoclonal antibodies protect aged rhesus macaques from SARS-CoV-2-induced immune activation and neuroinflammation.
Verma A, Hawes CE, Lakshmanappa YS, Roh JW, Schmidt BA, Dutra J, Louie W, Liu H, Ma ZM, Watanabe JK, Usachenko JL, Immareddy R, Sammak RL, Pollard R, Reader JR, Olstad KJ, Coffey LL, Kozlowski PA, Hartigan-O'Connor DJ, Nussenzweig M, Van Rompay KKA, Morrison JH, Iyer SS. Verma A, et al. Among authors: louie w. Cell Rep. 2021 Nov 2;37(5):109942. doi: 10.1016/j.celrep.2021.109942. Epub 2021 Oct 19. Cell Rep. 2021. PMID: 34706272 Free PMC article.
Two Sides of a Coin: a Zika Virus Mutation Selected in Pregnant Rhesus Macaques Promotes Fetal Infection in Mice but at a Cost of Reduced Fitness in Nonpregnant Macaques and Diminished Transmissibility by Vectors.
Lemos D, Stuart JB, Louie W, Singapuri A, Ramírez AL, Watanabe J, Usachenko J, Keesler RI, Sanchez-San Martin C, Li T, Martyn C, Oliveira G, Saraf S, Grubaugh ND, Andersen KG, Thissen J, Allen J, Borucki M, Tsetsarkin KA, Pletnev AG, Chiu CY, Van Rompay KKA, Coffey LL. Lemos D, et al. Among authors: louie w. J Virol. 2020 Nov 23;94(24):e01605-20. doi: 10.1128/JVI.01605-20. Print 2020 Nov 23. J Virol. 2020. PMID: 32999034 Free PMC article.
16 results