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33 results
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TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's β-amyloid oligomers in mice and monkeys.
Lourenco MV, Clarke JR, Frozza RL, Bomfim TR, Forny-Germano L, Batista AF, Sathler LB, Brito-Moreira J, Amaral OB, Silva CA, Freitas-Correa L, Espírito-Santo S, Campello-Costa P, Houzel JC, Klein WL, Holscher C, Carvalheira JB, Silva AM, Velloso LA, Munoz DP, Ferreira ST, De Felice FG. Lourenco MV, et al. Cell Metab. 2013 Dec 3;18(6):831-43. doi: 10.1016/j.cmet.2013.11.002. Cell Metab. 2013. PMID: 24315369
d-serine levels in Alzheimer's disease: implications for novel biomarker development.
Madeira C, Lourenco MV, Vargas-Lopes C, Suemoto CK, Brandão CO, Reis T, Leite RE, Laks J, Jacob-Filho W, Pasqualucci CA, Grinberg LT, Ferreira ST, Panizzutti R. Madeira C, et al. Among authors: lourenco mv. Transl Psychiatry. 2015 May 5;5(5):e561. doi: 10.1038/tp.2015.52. Transl Psychiatry. 2015. PMID: 25942042 Free PMC article.
Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice.
Brito-Moreira J, Lourenco MV, Oliveira MM, Ribeiro FC, Ledo JH, Diniz LP, Vital JFS, Magdesian MH, Melo HM, Barros-Aragão F, de Souza JM, Alves-Leon SV, Gomes FCA, Clarke JR, Figueiredo CP, De Felice FG, Ferreira ST. Brito-Moreira J, et al. Among authors: lourenco mv. J Biol Chem. 2017 May 5;292(18):7327-7337. doi: 10.1074/jbc.M116.761189. Epub 2017 Mar 10. J Biol Chem. 2017. PMID: 28283575 Free PMC article.
Amyloid-β oligomers transiently inhibit AMP-activated kinase and cause metabolic defects in hippocampal neurons.
Seixas da Silva GS, Melo HM, Lourenco MV, Lyra E Silva NM, de Carvalho MB, Alves-Leon SV, de Souza JM, Klein WL, da-Silva WS, Ferreira ST, De Felice FG. Seixas da Silva GS, et al. Among authors: lourenco mv. J Biol Chem. 2017 May 5;292(18):7395-7406. doi: 10.1074/jbc.M116.753525. Epub 2017 Mar 16. J Biol Chem. 2017. PMID: 28302722 Free PMC article.
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