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The TIGIT+ T regulatory cells subset associates with nosocomial infection and fatal outcome in COVID-19 patients under mechanical ventilation.
de Lima MHF, Machado CC, Nascimento DC, Silva CMS, Toller-Kawahisa JE, Rodrigues TS, Veras FP, Pontelli MC, Castro IA, Zamboni DS, Filho JA, Cunha TM, Arruda E, da Cunha LD, Oliveira RDR, Cunha FQ, Louzada-Junior P. de Lima MHF, et al. Sci Rep. 2023 Aug 21;13(1):13599. doi: 10.1038/s41598-023-39924-7. Sci Rep. 2023. PMID: 37604833 Free PMC article.
Inhibition of IL-6 signaling prevents serum-induced umbilical cord artery dysfunction from patients with severe COVID-19.
Almeida CR, Lima JF, Machado MR, Alves JV, Couto AES, Campos LCB, Avila-Mesquita CD, Auxiliadora-Martins M, Becari C, Louzada-Júnior P, Tostes RC, Lobato NS, Costa RM. Almeida CR, et al. Am J Physiol Regul Integr Comp Physiol. 2023 Apr 1;324(4):R435-R445. doi: 10.1152/ajpregu.00154.2022. Epub 2023 Feb 3. Am J Physiol Regul Integr Comp Physiol. 2023. PMID: 36737252 Free PMC article.
Cytokine storm in individuals with severe COVID-19 decreases endothelial cell antioxidant defense via downregulation of the Nrf2 transcriptional factor.
Rodrigues D, Machado MR, Alves JV, Fraga-Silva TFC, Martins RB, Campos LCB, Francisco DF, Couto AES, Bonato VLD, Arruda E, Becari C, Auxiliadora-Martins M, Louzada-Júnior P, Costa RM, Tostes RC. Rodrigues D, et al. Am J Physiol Heart Circ Physiol. 2023 Aug 1;325(2):H252-H263. doi: 10.1152/ajpheart.00096.2023. Epub 2023 Jun 16. Am J Physiol Heart Circ Physiol. 2023. PMID: 37327001 Free PMC article.
Colchicine reduces the activation of NLRP3 inflammasome in COVID-19 patients.
Amaral NB, Rodrigues TS, Giannini MC, Lopes MI, Bonjorno LP, Menezes PISO, Dib SM, Gigante SLG, Benatti MN, Rezek UC, Emrich-Filho LL, Sousa BA, Almeida SCL, Luppino-Assad R, Veras FP, Schneider AH, Leiria LOS, Cunha LD, Alves-Filho JC, Cunha TM, Arruda E, Miranda CH, Pazin-Filho A, Auxiliadora-Martins M, Borges MC, Fonseca BAL, Bollela VR, Del-Ben CM, Cunha FQ, Santana RC, Vilar FC, Zamboni DS, Louzada-Junior P, Oliveira RDR. Amaral NB, et al. Inflamm Res. 2023 May;72(5):895-899. doi: 10.1007/s00011-023-01718-y. Epub 2023 Mar 14. Inflamm Res. 2023. PMID: 36917217 Free PMC article. Clinical Trial.
Neutrophil extracellular traps mediate bone erosion in rheumatoid arthritis by enhancing RANKL-induced osteoclastogenesis.
Schneider AH, Taira TM, Públio GA, da Silva Prado D, Donate Yabuta PB, Dos Santos JC, Machado CC, de Souza FFL, Rodrigues Venturini LG, de Oliveira RDR, Cunha TM, Alves-Filho JC, Louzada-Júnior P, Aparecida da Silva T, Fukada SY, Cunha FQ. Schneider AH, et al. Among authors: louzada junior p. Br J Pharmacol. 2024 Feb;181(3):429-446. doi: 10.1111/bph.16227. Epub 2023 Sep 28. Br J Pharmacol. 2024. PMID: 37625900
141 results