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Transgenic, inducible RNAi in megakaryocytes and platelets in mice.
Takiguchi M, James C, Josefsson EC, Carmichael CL, Premsrirut PK, Lowe SW, Hamilton JR, Huang DC, Kile BT, Dickins RA. Takiguchi M, et al. Among authors: lowe sw. J Thromb Haemost. 2010 Dec;8(12):2751-6. doi: 10.1111/j.1538-7836.2010.04077.x. J Thromb Haemost. 2010. PMID: 21138522 Free PMC article.
Tumor-selective activity of RAS-GTP inhibition in pancreatic cancer.
Wasko UN, Jiang J, Dalton TC, Curiel-Garcia A, Edwards AC, Wang Y, Lee B, Orlen M, Tian S, Stalnecker CA, Drizyte-Miller K, Menard M, Dilly J, Sastra SA, Palermo CF, Hasselluhn MC, Decker-Farrell AR, Chang S, Jiang L, Wei X, Yang YC, Helland C, Courtney H, Gindin Y, Muonio K, Zhao R, Kemp SB, Clendenin C, Sor R, Vostrejs WP, Hibshman PS, Amparo AM, Hennessey C, Rees MG, Ronan MM, Roth JA, Brodbeck J, Tomassoni L, Bakir B, Socci ND, Herring LE, Barker NK, Wang J, Cleary JM, Wolpin BM, Chabot JA, Kluger MD, Manji GA, Tsai KY, Sekulic M, Lagana SM, Califano A, Quintana E, Wang Z, Smith JAM, Holderfield M, Wildes D, Lowe SW, Badgley MA, Aguirre AJ, Vonderheide RH, Stanger BZ, Baslan T, Der CJ, Singh M, Olive KP. Wasko UN, et al. Among authors: lowe sw. Nature. 2024 Apr 8. doi: 10.1038/s41586-024-07379-z. Online ahead of print. Nature. 2024. PMID: 38588697
Metastatic site influences driver gene function in pancreatic cancer.
Tsanov KM, Barriga FM, Ho YJ, Alonso-Curbelo D, Livshits G, Koche RP, Baslan T, Simon J, Tian S, Wuest AN, Luan W, Wilkinson JE, Masilionis I, Dimitrova N, Iacobuzio-Donahue CA, Chaligné R, Pe'er D, Massagué J, Lowe SW. Tsanov KM, et al. Among authors: lowe sw. bioRxiv [Preprint]. 2024 Mar 18:2024.03.17.585402. doi: 10.1101/2024.03.17.585402. bioRxiv. 2024. PMID: 38562717 Free PMC article. Preprint.
Author Correction: Senolytic CAR T cells reverse senescence-associated pathologies.
Amor C, Feucht J, Leibold J, Ho YJ, Zhu C, Alonso-Curbelo D, Mansilla-Soto J, Boyer JA, Li X, Giavridis T, Kulick A, Houlihan S, Peerschke E, Friedman SL, Ponomarev V, Piersigilli A, Sadelain M, Lowe SW. Amor C, et al. Among authors: lowe sw. Nature. 2024 Mar;627(8004):E9. doi: 10.1038/s41586-024-07197-3. Nature. 2024. PMID: 38383793 No abstract available.
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction.
Amor C, Fernández-Maestre I, Chowdhury S, Ho YJ, Nadella S, Graham C, Carrasco SE, Nnuji-John E, Feucht J, Hinterleitner C, Barthet VJA, Boyer JA, Mezzadra R, Wereski MG, Tuveson DA, Levine RL, Jones LW, Sadelain M, Lowe SW. Amor C, et al. Among authors: lowe sw. Nat Aging. 2024 Mar;4(3):336-349. doi: 10.1038/s43587-023-00560-5. Epub 2024 Jan 24. Nat Aging. 2024. PMID: 38267706 Free PMC article.
Solid tumor growth depends on an intricate equilibrium of malignant cell states.
Torborg SR, Grbovic-Huezo O, Singhal A, Holm M, Wu K, Han X, Ho YJ, Haglund C, Mitchell MJ, Lowe SW, Dow LE, Pitter KL, Sanchez-Rivera FJ, Levchenko A, Tammela T. Torborg SR, et al. Among authors: lowe sw. bioRxiv [Preprint]. 2023 Dec 30:2023.12.30.573100. doi: 10.1101/2023.12.30.573100. bioRxiv. 2023. PMID: 38234855 Free PMC article. Preprint.
354 results