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p53 is required for radiation-induced apoptosis in mouse thymocytes.
Lowe SW, Schmitt EM, Smith SW, Osborne BA, Jacks T. Lowe SW, et al. Nature. 1993 Apr 29;362(6423):847-9. doi: 10.1038/362847a0. Nature. 1993. PMID: 8479522
Suppression of apoptosis by bcl-2 does not prevent p53-mediated control of experimental metastasis and anchorage dependence.
Nikiforov MA, Kwek SS, Mehta R, Artwohl JE, Lowe SW, Gupta TD, Deichman GI, Gudkov AV. Nikiforov MA, et al. Oncogene. 1997 Dec 18;15(25):3007-12. doi: 10.1038/sj.onc.1201723. Oncogene. 1997. PMID: 9444949
Genetic analysis of chemoresistance in primary murine lymphomas.
Schmitt CA, Rosenthal CT, Lowe SW. Schmitt CA, et al. Nat Med. 2000 Sep;6(9):1029-35. doi: 10.1038/79542. Nat Med. 2000. PMID: 10973324
Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation.
Koumenis C, Alarcon R, Hammond E, Sutphin P, Hoffman W, Murphy M, Derr J, Taya Y, Lowe SW, Kastan M, Giaccia A. Koumenis C, et al. Mol Cell Biol. 2001 Feb;21(4):1297-310. doi: 10.1128/MCB.21.4.1297-1310.2001. Mol Cell Biol. 2001. PMID: 11158315 Free PMC article.
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma.
Soengas MS, Capodieci P, Polsky D, Mora J, Esteller M, Opitz-Araya X, McCombie R, Herman JG, Gerald WL, Lazebnik YA, Cordón-Cardó C, Lowe SW. Soengas MS, et al. Nature. 2001 Jan 11;409(6817):207-11. doi: 10.1038/35051606. Nature. 2001. PMID: 11196646
The price of tumour suppression?
Ferbeyre G, Lowe SW. Ferbeyre G, et al. Nature. 2002 Jan 3;415(6867):26-7. doi: 10.1038/415026a. Nature. 2002. PMID: 11780097 No abstract available.
Apoptosis and chemoresistance in transgenic cancer models.
Schmitt CA, Lowe SW. Schmitt CA, et al. J Mol Med (Berl). 2002 Mar;80(3):137-46. doi: 10.1007/s00109-001-0293-3. Epub 2001 Nov 7. J Mol Med (Berl). 2002. PMID: 11894140 Review.
Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23.
Li J, Yang Y, Peng Y, Austin RJ, van Eyndhoven WG, Nguyen KC, Gabriele T, McCurrach ME, Marks JR, Hoey T, Lowe SW, Powers S. Li J, et al. Nat Genet. 2002 Jun;31(2):133-4. doi: 10.1038/ng888. Epub 2002 May 20. Nat Genet. 2002. PMID: 12021784
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