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Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion.
van de Wall E, Leshan R, Xu AW, Balthasar N, Coppari R, Liu SM, Jo YH, MacKenzie RG, Allison DB, Dun NJ, Elmquist J, Lowell BB, Barsh GS, de Luca C, Myers MG Jr, Schwartz GJ, Chua SC Jr. van de Wall E, et al. Among authors: lowell bb. Endocrinology. 2008 Apr;149(4):1773-85. doi: 10.1210/en.2007-1132. Epub 2007 Dec 27. Endocrinology. 2008. PMID: 18162515 Free PMC article.
Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis.
Dhillon H, Zigman JM, Ye C, Lee CE, McGovern RA, Tang V, Kenny CD, Christiansen LM, White RD, Edelstein EA, Coppari R, Balthasar N, Cowley MA, Chua S Jr, Elmquist JK, Lowell BB. Dhillon H, et al. Among authors: lowell bb. Neuron. 2006 Jan 19;49(2):191-203. doi: 10.1016/j.neuron.2005.12.021. Neuron. 2006. PMID: 16423694 Free article.
Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility.
Hill JW, Elias CF, Fukuda M, Williams KW, Berglund ED, Holland WL, Cho YR, Chuang JC, Xu Y, Choi M, Lauzon D, Lee CE, Coppari R, Richardson JA, Zigman JM, Chua S, Scherer PE, Lowell BB, Brüning JC, Elmquist JK. Hill JW, et al. Among authors: lowell bb. Cell Metab. 2010 Apr 7;11(4):286-97. doi: 10.1016/j.cmet.2010.03.002. Cell Metab. 2010. PMID: 20374961 Free PMC article.
214 results