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Protease inhibitors targeting coronavirus and filovirus entry.
Zhou Y, Vedantham P, Lu K, Agudelo J, Carrion R Jr, Nunneley JW, Barnard D, Pöhlmann S, McKerrow JH, Renslo AR, Simmons G. Zhou Y, et al. Among authors: lu k. Antiviral Res. 2015 Apr;116:76-84. doi: 10.1016/j.antiviral.2015.01.011. Epub 2015 Feb 7. Antiviral Res. 2015. PMID: 25666761 Free PMC article.
No evidence for XMRV nucleic acids, infectious virus or anti-XMRV antibodies in Canadian patients with chronic fatigue syndrome.
Steffen I, Tyrrell DL, Stein E, Montalvo L, Lee TH, Zhou Y, Lu K, Switzer WM, Tang S, Jia H, Hockman D, Santer DM, Logan M, Landi A, Law J, Houghton M, Simmons G. Steffen I, et al. Among authors: lu k. PLoS One. 2011;6(11):e27870. doi: 10.1371/journal.pone.0027870. Epub 2011 Nov 17. PLoS One. 2011. PMID: 22114717 Free PMC article.
Filoviruses utilize glycosaminoglycans for their attachment to target cells.
Salvador B, Sexton NR, Carrion R Jr, Nunneley J, Patterson JL, Steffen I, Lu K, Muench MO, Lembo D, Simmons G. Salvador B, et al. Among authors: lu k. J Virol. 2013 Mar;87(6):3295-304. doi: 10.1128/JVI.01621-12. Epub 2013 Jan 9. J Virol. 2013. PMID: 23302881 Free PMC article.
A neutralizing monoclonal antibody targeting the acid-sensitive region in chikungunya virus E2 protects from disease.
Selvarajah S, Sexton NR, Kahle KM, Fong RH, Mattia KA, Gardner J, Lu K, Liss NM, Salvador B, Tucker DF, Barnes T, Mabila M, Zhou X, Rossini G, Rucker JB, Sanders DA, Suhrbier A, Sambri V, Michault A, Muench MO, Doranz BJ, Simmons G. Selvarajah S, et al. Among authors: lu k. PLoS Negl Trop Dis. 2013 Sep 12;7(9):e2423. doi: 10.1371/journal.pntd.0002423. eCollection 2013. PLoS Negl Trop Dis. 2013. PMID: 24069479 Free PMC article.
Exposure of epitope residues on the outer face of the chikungunya virus envelope trimer determines antibody neutralizing efficacy.
Fong RH, Banik SS, Mattia K, Barnes T, Tucker D, Liss N, Lu K, Selvarajah S, Srinivasan S, Mabila M, Miller A, Muench MO, Michault A, Rucker JB, Paes C, Simmons G, Kahle KM, Doranz BJ. Fong RH, et al. Among authors: lu k. J Virol. 2014 Dec;88(24):14364-79. doi: 10.1128/JVI.01943-14. Epub 2014 Oct 1. J Virol. 2014. PMID: 25275138 Free PMC article.
5,651 results