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Year Number of Results
1990 2
1991 1
1992 2
1993 4
1994 2
1995 3
1996 2
1997 3
1998 3
1999 4
2000 9
2001 12
2002 10
2003 11
2004 5
2005 7
2006 10
2007 8
2008 6
2009 4
2010 5
2011 11
2012 14
2013 3
2014 5
2015 10
2016 9
2017 10
2018 10
2019 10
2020 6
2021 9
2022 2
2023 5
2024 7

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206 results

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Page 1
Reciprocal antagonism of PIN1-APC/CCDH1 governs mitotic protein stability and cell cycle entry.
Ke S, Dang F, Wang L, Chen JY, Naik MT, Li W, Thavamani A, Kim N, Naik NM, Sui H, Tang W, Qiu C, Koikawa K, Batalini F, Stern Gatof E, Isaza DA, Patel JM, Wang X, Clohessy JG, Heng YJ, Lahav G, Liu Y, Gray NS, Zhou XZ, Wei W, Wulf GM, Lu KP. Ke S, et al. Among authors: lu kp. Nat Commun. 2024 Apr 15;15(1):3220. doi: 10.1038/s41467-024-47427-w. Nat Commun. 2024. PMID: 38622115 Free PMC article.
Author Correction: The IL-33-PIN1-IRAK-M axis is critical for type 2 immunity in IL-33-induced allergic airway inflammation.
Nechama M, Kwon J, Wei S, Tun-Kyi A, Welner RS, Ben-Dov IZ, Arredouani MS, Asara JM, Chen CH, Tsai CY, Nelson KF, Kobayashi KS, Israel E, Zhou XZ, Nicholson LK, Lu KP. Nechama M, et al. Among authors: lu kp. Nat Commun. 2023 Jun 19;14(1):3622. doi: 10.1038/s41467-023-39297-5. Nat Commun. 2023. PMID: 37336880 Free PMC article. No abstract available.
Reciprocal inhibition of PIN1 and APC/CCDH1 controls timely G1/S transition and creates therapeutic vulnerability.
Ke S, Dang F, Wang L, Chen JY, Naik MT, Thavamani A, Liu Y, Li W, Kim N, Naik NM, Sui H, Tang W, Qiu C, Koikawa K, Batalini F, Wang X, Clohessy JG, Heng YJ, Lahav G, Gray NS, Zho XZ, Wei W, Wulf GM, Lu KP. Ke S, et al. Among authors: lu kp. Res Sq [Preprint]. 2023 Jan 19:rs.3.rs-2447544. doi: 10.21203/rs.3.rs-2447544/v1. Res Sq. 2023. PMID: 36711754 Free PMC article. Preprint.
Erratum for Wang et al., "Clinically Applicable System for Rapidly Predicting Enterococcus faecium Susceptibility to Vancomycin".
Wang HY, Chung CR, Chen CJ, Lu KP, Tseng YJ, Chang TH, Wu MH, Huang WT, Lin TW, Liu TP, Lee TY, Horng JT, Lu JJ. Wang HY, et al. Among authors: lu kp. Microbiol Spectr. 2022 Feb 23;10(1):e0261021. doi: 10.1128/spectrum.02610-21. Epub 2022 Jan 19. Microbiol Spectr. 2022. PMID: 35044194 Free PMC article. No abstract available.
Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy.
Koikawa K, Kibe S, Suizu F, Sekino N, Kim N, Manz TD, Pinch BJ, Akshinthala D, Verma A, Gaglia G, Nezu Y, Ke S, Qiu C, Ohuchida K, Oda Y, Lee TH, Wegiel B, Clohessy JG, London N, Santagata S, Wulf GM, Hidalgo M, Muthuswamy SK, Nakamura M, Gray NS, Zhou XZ, Lu KP. Koikawa K, et al. Among authors: lu kp. Cell. 2021 Sep 2;184(18):4753-4771.e27. doi: 10.1016/j.cell.2021.07.020. Epub 2021 Aug 12. Cell. 2021. PMID: 34388391 Free PMC article.
Cis P-tau underlies vascular contribution to cognitive impairment and dementia and can be effectively targeted by immunotherapy in mice.
Qiu C, Albayram O, Kondo A, Wang B, Kim N, Arai K, Tsai CY, Bassal MA, Herbert MK, Washida K, Angeli P, Kozono S, Stucky JE, Baxley S, Lin YM, Sun Y, Rotenberg A, Caldarone BJ, Bigio EH, Chen X, Tenen DG, Zeidel M, Lo EH, Zhou XZ, Lu KP. Qiu C, et al. Among authors: lu kp. Sci Transl Med. 2021 Jun 2;13(596):eaaz7615. doi: 10.1126/scitranslmed.aaz7615. Sci Transl Med. 2021. PMID: 34078745 Free PMC article.
Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo.
Dubiella C, Pinch BJ, Koikawa K, Zaidman D, Poon E, Manz TD, Nabet B, He S, Resnick E, Rogel A, Langer EM, Daniel CJ, Seo HS, Chen Y, Adelmant G, Sharifzadeh S, Ficarro SB, Jamin Y, Martins da Costa B, Zimmerman MW, Lian X, Kibe S, Kozono S, Doctor ZM, Browne CM, Yang A, Stoler-Barak L, Shah RB, Vangos NE, Geffken EA, Oren R, Koide E, Sidi S, Shulman Z, Wang C, Marto JA, Dhe-Paganon S, Look T, Zhou XZ, Lu KP, Sears RC, Chesler L, Gray NS, London N. Dubiella C, et al. Among authors: lu kp. Nat Chem Biol. 2021 Sep;17(9):954-963. doi: 10.1038/s41589-021-00786-7. Epub 2021 May 10. Nat Chem Biol. 2021. PMID: 33972797 Free PMC article.
The Pin1-CaMKII-AMPA Receptor Axis Regulates Epileptic Susceptibility.
Hou X, Yang F, Li A, Zhao D, Ma N, Chen L, Lin S, Lin Y, Wang L, Yan X, Zheng M, Lee TH, Zhou XZ, Lu KP, Liu H. Hou X, et al. Among authors: lu kp. Cereb Cortex. 2021 May 10;31(6):3082-3095. doi: 10.1093/cercor/bhab004. Cereb Cortex. 2021. PMID: 33569579 Free PMC article.
The Association Between Cancer and Spousal Rate of Memory Decline: A Negative Control Study to Evaluate (Unmeasured) Social Confounding of the Cancer-memory Relationship.
Ospina-Romero M, Brenowitz WD, Glymour MM, Mayeda ER, Graff RE, Witte JS, Ackley SF, Lu KP, Kobayashi LC. Ospina-Romero M, et al. Among authors: lu kp. Alzheimer Dis Assoc Disord. 2021 Jul-Sep 01;35(3):271-274. doi: 10.1097/WAD.0000000000000398. Alzheimer Dis Assoc Disord. 2021. PMID: 32568784 Free PMC article.
Identification of a potent and selective covalent Pin1 inhibitor.
Pinch BJ, Doctor ZM, Nabet B, Browne CM, Seo HS, Mohardt ML, Kozono S, Lian X, Manz TD, Chun Y, Kibe S, Zaidman D, Daitchman D, Yeoh ZC, Vangos NE, Geffken EA, Tan L, Ficarro SB, London N, Marto JA, Buratowski S, Dhe-Paganon S, Zhou XZ, Lu KP, Gray NS. Pinch BJ, et al. Among authors: lu kp. Nat Chem Biol. 2020 Sep;16(9):979-987. doi: 10.1038/s41589-020-0550-9. Epub 2020 Jun 1. Nat Chem Biol. 2020. PMID: 32483379 Free PMC article.
An IRAK1-PIN1 signalling axis drives intrinsic tumour resistance to radiation therapy.
Liu PH, Shah RB, Li Y, Arora A, Ung PM, Raman R, Gorbatenko A, Kozono S, Zhou XZ, Brechin V, Barbaro JM, Thompson R, White RM, Aguirre-Ghiso JA, Heymach JV, Lu KP, Silva JM, Panageas KS, Schlessinger A, Maki RG, Skinner HD, de Stanchina E, Sidi S. Liu PH, et al. Among authors: lu kp. Nat Cell Biol. 2019 Feb;21(2):203-213. doi: 10.1038/s41556-018-0260-7. Epub 2019 Jan 21. Nat Cell Biol. 2019. PMID: 30664786 Free PMC article.
SPOP Promotes Nanog Destruction to Suppress Stem Cell Traits and Prostate Cancer Progression.
Zhang J, Chen M, Zhu Y, Dai X, Dang F, Ren J, Ren S, Shulga YV, Beca F, Gan W, Wu F, Lin YM, Zhou X, DeCaprio JA, Beck AH, Lu KP, Huang J, Zhao C, Sun Y, Gao X, Pandolfi PP, Wei W. Zhang J, et al. Among authors: lu kp. Dev Cell. 2019 Feb 11;48(3):329-344.e5. doi: 10.1016/j.devcel.2018.11.035. Epub 2018 Dec 27. Dev Cell. 2019. PMID: 30595538 Free PMC article.
Correction to: Pin1 inhibition exerts potent activity against acute myeloid leukemia through blocking multiple cancer-driving pathways.
Lian X, Lin YM, Kozono S, Herbert MK, Li X, Yuan X, Guo J, Guo Y, Tang M, Lin J, Huang Y, Wang B, Qiu C, Tsai CY, Xie J, Gao ZJ, Wu Y, Liu H, Zhou XZ, Lu KP, Chen Y. Lian X, et al. Among authors: lu kp. J Hematol Oncol. 2018 Jul 11;11(1):94. doi: 10.1186/s13045-018-0634-0. J Hematol Oncol. 2018. PMID: 29996897 Free PMC article.
Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model.
Tagge CA, Fisher AM, Minaeva OV, Gaudreau-Balderrama A, Moncaster JA, Zhang XL, Wojnarowicz MW, Casey N, Lu H, Kokiko-Cochran ON, Saman S, Ericsson M, Onos KD, Veksler R, Senatorov VV Jr, Kondo A, Zhou XZ, Miry O, Vose LR, Gopaul KR, Upreti C, Nowinski CJ, Cantu RC, Alvarez VE, Hildebrandt AM, Franz ES, Konrad J, Hamilton JA, Hua N, Tripodis Y, Anderson AT, Howell GR, Kaufer D, Hall GF, Lu KP, Ransohoff RM, Cleveland RO, Kowall NW, Stein TD, Lamb BT, Huber BR, Moss WC, Friedman A, Stanton PK, McKee AC, Goldstein LE. Tagge CA, et al. Among authors: lu kp. Brain. 2018 Feb 1;141(2):422-458. doi: 10.1093/brain/awx350. Brain. 2018. PMID: 29360998 Free PMC article.
Cis P-tau is induced in clinical and preclinical brain injury and contributes to post-injury sequelae.
Albayram O, Kondo A, Mannix R, Smith C, Tsai CY, Li C, Herbert MK, Qiu J, Monuteaux M, Driver J, Yan S, Gormley W, Puccio AM, Okonkwo DO, Lucke-Wold B, Bailes J, Meehan W, Zeidel M, Lu KP, Zhou XZ. Albayram O, et al. Among authors: lu kp. Nat Commun. 2017 Oct 17;8(1):1000. doi: 10.1038/s41467-017-01068-4. Nat Commun. 2017. PMID: 29042562 Free PMC article.
Military Blast Injury and Chronic Neurodegeneration: Research Presentations from the 2015 International State-of-the-Science Meeting.
Agoston D, Arun P, Bellgowan P, Broglio S, Cantu R, Cook D, da Silva UO, Dickstein D, Elder G, Fudge E, Gandy S, Gill J, Glenn JF, Gupta RK, Hinds S, Hoffman S, Lattimore T, Lin A, Lu KP, Maroon J, Okonkwo D, Perl D, Robinson M, Rosen C, Smith D. Agoston D, et al. Among authors: lu kp. J Neurotrauma. 2017 Sep;34(S1):S6-S17. doi: 10.1089/neu.2017.5220. J Neurotrauma. 2017. PMID: 28937955 Free PMC article.
Critical role of XBP1 in cancer signalling is regulated by PIN1.
Chae U, Park SJ, Kim B, Wei S, Min JS, Lee JH, Park SH, Lee AH, Lu KP, Lee DS, Min SH. Chae U, et al. Among authors: lu kp. Biochem J. 2016 Sep 1;473(17):2603-10. doi: 10.1042/BCJ20160482. Epub 2016 Jun 22. Biochem J. 2016. PMID: 27334111
Prolyl Isomerase Pin1 Regulates Axon Guidance by Stabilizing CRMP2A Selectively in Distal Axons.
Balastik M, Zhou XZ, Alberich-Jorda M, Weissova R, Žiak J, Pazyra-Murphy MF, Cosker KE, Machonova O, Kozmikova I, Chen CH, Pastorino L, Asara JM, Cole A, Sutherland C, Segal RA, Lu KP. Balastik M, et al. Among authors: lu kp. Cell Rep. 2015 Oct 27;13(4):812-828. doi: 10.1016/j.celrep.2015.09.026. Epub 2015 Oct 17. Cell Rep. 2015. PMID: 26489457 Free PMC article.
Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy.
Kondo A, Shahpasand K, Mannix R, Qiu J, Moncaster J, Chen CH, Yao Y, Lin YM, Driver JA, Sun Y, Wei S, Luo ML, Albayram O, Huang P, Rotenberg A, Ryo A, Goldstein LE, Pascual-Leone A, McKee AC, Meehan W, Zhou XZ, Lu KP. Kondo A, et al. Among authors: lu kp. Nature. 2015 Jul 23;523(7561):431-436. doi: 10.1038/nature14658. Epub 2015 Jul 15. Nature. 2015. PMID: 26176913 Free PMC article.
Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer.
Wei S, Kozono S, Kats L, Nechama M, Li W, Guarnerio J, Luo M, You MH, Yao Y, Kondo A, Hu H, Bozkurt G, Moerke NJ, Cao S, Reschke M, Chen CH, Rego EM, Lo-Coco F, Cantley LC, Lee TH, Wu H, Zhang Y, Pandolfi PP, Zhou XZ, Lu KP. Wei S, et al. Among authors: lu kp. Nat Med. 2015 May;21(5):457-66. doi: 10.1038/nm.3839. Epub 2015 Apr 13. Nat Med. 2015. PMID: 25849135 Free PMC article.
Theileria parasites secrete a prolyl isomerase to maintain host leukocyte transformation.
Marsolier J, Perichon M, DeBarry JD, Villoutreix BO, Chluba J, Lopez T, Garrido C, Zhou XZ, Lu KP, Fritsch L, Ait-Si-Ali S, Mhadhbi M, Medjkane S, Weitzman JB. Marsolier J, et al. Among authors: lu kp. Nature. 2015 Apr 16;520(7547):378-82. doi: 10.1038/nature14044. Epub 2015 Jan 26. Nature. 2015. PMID: 25624101 Free PMC article.
Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus.
Liu P, Begley M, Michowski W, Inuzuka H, Ginzberg M, Gao D, Tsou P, Gan W, Papa A, Kim BM, Wan L, Singh A, Zhai B, Yuan M, Wang Z, Gygi SP, Lee TH, Lu KP, Toker A, Pandolfi PP, Asara JM, Kirschner MW, Sicinski P, Cantley L, Wei W. Liu P, et al. Among authors: lu kp. Nature. 2014 Apr 24;508(7497):541-5. doi: 10.1038/nature13079. Epub 2014 Mar 9. Nature. 2014. PMID: 24670654 Free PMC article.
SENP1 deSUMOylates and regulates Pin1 protein activity and cellular function.
Chen CH, Chang CC, Lee TH, Luo M, Huang P, Liao PH, Wei S, Li FA, Chen RH, Zhou XZ, Shih HM, Lu KP. Chen CH, et al. Among authors: lu kp. Cancer Res. 2013 Jul 1;73(13):3951-62. doi: 10.1158/0008-5472.CAN-12-4360. Epub 2013 Apr 30. Cancer Res. 2013. PMID: 23633483 Free PMC article.
Regulation of cardiac hypertrophic signaling by prolyl isomerase Pin1.
Toko H, Konstandin MH, Doroudgar S, Ormachea L, Joyo E, Joyo AY, Din S, Gude NA, Collins B, Völkers M, Thuerauf DJ, Glembotski CC, Chen CH, Lu KP, Müller OJ, Uchida T, Sussman MA. Toko H, et al. Among authors: lu kp. Circ Res. 2013 Apr 26;112(9):1244-52. doi: 10.1161/CIRCRESAHA.113.301084. Epub 2013 Mar 13. Circ Res. 2013. PMID: 23487407 Free PMC article.
JNK3 perpetuates metabolic stress induced by Aβ peptides.
Yoon SO, Park DJ, Ryu JC, Ozer HG, Tep C, Shin YJ, Lim TH, Pastorino L, Kunwar AJ, Walton JC, Nagahara AH, Lu KP, Nelson RJ, Tuszynski MH, Huang K. Yoon SO, et al. Among authors: lu kp. Neuron. 2012 Sep 6;75(5):824-37. doi: 10.1016/j.neuron.2012.06.024. Neuron. 2012. PMID: 22958823 Free PMC article.
Risk factors of urinary frequency among women aged 60 and older in Taiwan.
Hsieh CH, Chang WC, Hsu MI, Chiang HS, Chang ST, Lee MC, Lee MS, Lu KP, Su TH, Lee SH, Chen FM. Hsieh CH, et al. Among authors: lu kp. Taiwan J Obstet Gynecol. 2010 Sep;49(3):260-5. doi: 10.1016/S1028-4559(10)60058-7. Taiwan J Obstet Gynecol. 2010. PMID: 21056308 Free article.
Prevalence of urinary frequency among women aged 60 years and older in Taiwan.
Hsieh CH, Chang WC, Hsu MI, Lee MC, Lee MS, Chiang HS, Chang ST, Su TH, Lu KP, Lee SH, Chen FM. Hsieh CH, et al. Among authors: lu kp. Taiwan J Obstet Gynecol. 2009 Dec;48(4):385-8. doi: 10.1016/S1028-4559(09)60328-4. Taiwan J Obstet Gynecol. 2009. PMID: 20045760 Free article.
Pinning down HER2-ER crosstalk in SMRT regulation.
Ryo A, Wulf G, Lee TH, Lu KP. Ryo A, et al. Among authors: lu kp. Trends Biochem Sci. 2009 Apr;34(4):162-5. doi: 10.1016/j.tibs.2008.12.004. Epub 2009 Mar 9. Trends Biochem Sci. 2009. PMID: 19269830
Relative resistance of Cdk5-phosphorylated CRMP2 to dephosphorylation.
Cole AR, Soutar MP, Rembutsu M, van Aalten L, Hastie CJ, McLauchlan H, Peggie M, Balastik M, Lu KP, Sutherland C. Cole AR, et al. Among authors: lu kp. J Biol Chem. 2008 Jun 27;283(26):18227-37. doi: 10.1074/jbc.M801645200. Epub 2008 May 6. J Biol Chem. 2008. PMID: 18460467 Free PMC article.
Structural basis for high-affinity peptide inhibition of human Pin1.
Zhang Y, Daum S, Wildemann D, Zhou XZ, Verdecia MA, Bowman ME, Lücke C, Hunter T, Lu KP, Fischer G, Noel JP. Zhang Y, et al. Among authors: lu kp. ACS Chem Biol. 2007 May 22;2(5):320-8. doi: 10.1021/cb7000044. ACS Chem Biol. 2007. PMID: 17518432 Free PMC article.
Pathogenic mechanisms in Alzheimer's disease.
Pastorino L, Lu KP. Pastorino L, et al. Among authors: lu kp. Eur J Pharmacol. 2006 Sep 1;545(1):29-38. doi: 10.1016/j.ejphar.2006.06.078. Epub 2006 Jul 4. Eur J Pharmacol. 2006. PMID: 16904664 Review.
Novel genomic targets in oxidant-induced vascular injury.
Partridge CR, Williams ES, Barhoumi R, Tadesse MG, Johnson CD, Lu KP, Meininger GA, Wilson E, Ramos KS. Partridge CR, et al. Among authors: lu kp. J Mol Cell Cardiol. 2005 Jun;38(6):983-96. doi: 10.1016/j.yjmcc.2005.03.006. Epub 2005 Apr 19. J Mol Cell Cardiol. 2005. PMID: 15910882
Regulation of Raf-1 by direct feedback phosphorylation.
Dougherty MK, Müller J, Ritt DA, Zhou M, Zhou XZ, Copeland TD, Conrads TP, Veenstra TD, Lu KP, Morrison DK. Dougherty MK, et al. Among authors: lu kp. Mol Cell. 2005 Jan 21;17(2):215-24. doi: 10.1016/j.molcel.2004.11.055. Mol Cell. 2005. PMID: 15664191 Free article.
Pinning down phosphorylated tau and tauopathies.
Lim J, Lu KP. Lim J, et al. Among authors: lu kp. Biochim Biophys Acta. 2005 Jan 3;1739(2-3):311-22. doi: 10.1016/j.bbadis.2004.10.003. Epub 2004 Nov 30. Biochim Biophys Acta. 2005. PMID: 15615648 Free article. Review.
Function of Drg1/Rit42 in p53-dependent mitotic spindle checkpoint.
Kim KT, Ongusaha PP, Hong YK, Kurdistani SK, Nakamura M, Lu KP, Lee SW. Kim KT, et al. Among authors: lu kp. J Biol Chem. 2004 Sep 10;279(37):38597-602. doi: 10.1074/jbc.M400781200. Epub 2004 Jul 9. J Biol Chem. 2004. PMID: 15247272 Free article.
The prolyl isomerase Pin1 in breast development and cancer.
Wulf G, Ryo A, Liou YC, Lu KP. Wulf G, et al. Among authors: lu kp. Breast Cancer Res. 2003;5(2):76-82. doi: 10.1186/bcr572. Epub 2003 Jan 28. Breast Cancer Res. 2003. PMID: 12631385 Free PMC article. Review.
A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1.
Songyang Z, Lu KP, Kwon YT, Tsai LH, Filhol O, Cochet C, Brickey DA, Soderling TR, Bartleson C, Graves DJ, DeMaggio AJ, Hoekstra MF, Blenis J, Hunter T, Cantley LC. Songyang Z, et al. Among authors: lu kp. Mol Cell Biol. 1996 Nov;16(11):6486-93. doi: 10.1128/MCB.16.11.6486. Mol Cell Biol. 1996. PMID: 8887677 Free PMC article.
206 results