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In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation.
Liao HK, Hatanaka F, Araoka T, Reddy P, Wu MZ, Sui Y, Yamauchi T, Sakurai M, O'Keefe DD, Núñez-Delicado E, Guillen P, Campistol JM, Wu CJ, Lu LF, Esteban CR, Izpisua Belmonte JC. Liao HK, et al. Among authors: lu lf. Cell. 2017 Dec 14;171(7):1495-1507.e15. doi: 10.1016/j.cell.2017.10.025. Epub 2017 Dec 7. Cell. 2017. PMID: 29224783 Free PMC article.
miR-23∼27∼24 clusters control effector T cell differentiation and function.
Cho S, Wu CJ, Yasuda T, Cruz LO, Khan AA, Lin LL, Nguyen DT, Miller M, Lee HM, Kuo ML, Broide DH, Rajewsky K, Rudensky AY, Lu LF. Cho S, et al. Among authors: lu lf. J Exp Med. 2016 Feb 8;213(2):235-49. doi: 10.1084/jem.20150990. Epub 2016 Feb 1. J Exp Med. 2016. PMID: 26834155 Free PMC article.
A Novel miR-24-TCF1 Axis in Modulating Effector T Cell Responses.
Cho S, Wu CJ, Nguyen DT, Lin LL, Chen MC, Khan AA, Yang BH, Fu W, Lu LF. Cho S, et al. Among authors: lu lf. J Immunol. 2017 May 15;198(10):3919-3926. doi: 10.4049/jimmunol.1601404. Epub 2017 Apr 12. J Immunol. 2017. PMID: 28404635 Free PMC article.
MicroRNA in Immune Regulation.
Wu CJ, Lu LF. Wu CJ, et al. Among authors: lu lf. Curr Top Microbiol Immunol. 2017;410:249-267. doi: 10.1007/82_2017_65. Curr Top Microbiol Immunol. 2017. PMID: 28900683 Free PMC article.
miR-25/93 mediates hypoxia-induced immunosuppression by repressing cGAS.
Wu MZ, Cheng WC, Chen SF, Nieh S, O'Connor C, Liu CL, Tsai WW, Wu CJ, Martin L, Lin YS, Wu KJ, Lu LF, Izpisua Belmonte JC. Wu MZ, et al. Among authors: lu lf. Nat Cell Biol. 2017 Oct;19(10):1286-1296. doi: 10.1038/ncb3615. Epub 2017 Sep 18. Nat Cell Biol. 2017. PMID: 28920955 Free PMC article.
TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8+ T cell exhaustion.
Seo H, Chen J, González-Avalos E, Samaniego-Castruita D, Das A, Wang YH, López-Moyado IF, Georges RO, Zhang W, Onodera A, Wu CJ, Lu LF, Hogan PG, Bhandoola A, Rao A. Seo H, et al. Among authors: lu lf. Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12410-12415. doi: 10.1073/pnas.1905675116. Epub 2019 May 31. Proc Natl Acad Sci U S A. 2019. PMID: 31152140 Free PMC article.
MiR-23~27~24-mediated control of humoral immunity reveals a TOX-driven regulatory circuit in follicular helper T cell differentiation.
Wu CJ, Cho S, Huang HY, Lu CH, Russ J, Cruz LO, da Cunha FF, Chen MC, Lin LL, Warner LM, Liao HK, Utzschneider DT, Quon S, Berner J, Camara NOS, Zehn D, Belmonte JCI, Chen LC, Huang SF, Kuo ML, Lu LF. Wu CJ, et al. Among authors: lu lf, lu ch. Sci Adv. 2019 Dec 11;5(12):eaaw1715. doi: 10.1126/sciadv.aaw1715. eCollection 2019 Dec. Sci Adv. 2019. PMID: 31844658 Free PMC article.
T Regulatory Cells Support Plasma Cell Populations in the Bone Marrow.
Glatman Zaretsky A, Konradt C, Dépis F, Wing JB, Goenka R, Atria DG, Silver JS, Cho S, Wolf AI, Quinn WJ, Engiles JB, Brown DC, Beiting D, Erikson J, Allman D, Cancro MP, Sakaguchi S, Lu LF, Benoist CO, Hunter CA. Glatman Zaretsky A, et al. Among authors: lu lf. Cell Rep. 2017 Feb 21;18(8):1906-1916. doi: 10.1016/j.celrep.2017.01.067. Cell Rep. 2017. PMID: 28228257 Free PMC article.
181 results