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AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53.
Kalous O, Conklin D, Desai AJ, Dering J, Goldstein J, Ginther C, Anderson L, Lu M, Kolarova T, Eckardt MA, Langerød A, Børresen-Dale AL, Slamon DJ, Finn RS. Kalous O, et al. Among authors: lu m. Breast Cancer Res Treat. 2013 Oct;141(3):397-408. doi: 10.1007/s10549-013-2702-z. Epub 2013 Oct 5. Breast Cancer Res Treat. 2013. PMID: 24091768
Targeted inhibition of EG-1 blocks breast tumor growth.
Lu M, Sartippour MR, Zhang L, Norris AJ, Brooks MN. Lu M, et al. Cancer Biol Ther. 2007 Jun;6(6):936-41. doi: 10.4161/cbt.6.6.4189. Epub 2007 Mar 26. Cancer Biol Ther. 2007. PMID: 17568184
Nitroxyl inhibits breast tumor growth and angiogenesis.
Norris AJ, Sartippour MR, Lu M, Park T, Rao JY, Jackson MI, Fukuto JM, Brooks MN. Norris AJ, et al. Among authors: lu m. Int J Cancer. 2008 Apr 15;122(8):1905-10. doi: 10.1002/ijc.23305. Int J Cancer. 2008. PMID: 18076071 Free article.
The novel gene EG-1 stimulates cellular proliferation.
Lu M, Zhang L, Maul RS, Sartippour MR, Norris A, Whitelegge J, Rao JY, Brooks MN. Lu M, et al. Cancer Res. 2005 Jul 15;65(14):6159-66. doi: 10.1158/0008-5472.CAN-04-4016. Cancer Res. 2005. PMID: 16024617
The combination of green tea and tamoxifen is effective against breast cancer.
Sartippour MR, Pietras R, Marquez-Garban DC, Chen HW, Heber D, Henning SM, Sartippour G, Zhang L, Lu M, Weinberg O, Rao JY, Brooks MN. Sartippour MR, et al. Among authors: lu m. Carcinogenesis. 2006 Dec;27(12):2424-33. doi: 10.1093/carcin/bgl066. Epub 2006 Jun 19. Carcinogenesis. 2006. PMID: 16785249
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