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22,266 results
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Hybrid compounds as new Bcr/Abl inhibitors.
Wang D, Zhang Z, Lu X, Feng Y, Luo K, Gan J, Yingxue L, Wan J, Li X, Zhang F, Tu Z, Cai Q, Ren X, Ding K. Wang D, et al. Among authors: lu x. Bioorg Med Chem Lett. 2011 Apr 1;21(7):1965-8. doi: 10.1016/j.bmcl.2011.02.029. Epub 2011 Feb 13. Bioorg Med Chem Lett. 2011. PMID: 21376587
New thiazole carboxamides as potent inhibitors of Akt kinases.
Chang S, Zhang Z, Zhuang X, Luo J, Cao X, Li H, Tu Z, Lu X, Ren X, Ding K. Chang S, et al. Among authors: lu x. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1208-12. doi: 10.1016/j.bmcl.2011.11.080. Epub 2011 Nov 30. Bioorg Med Chem Lett. 2012. PMID: 22172705
Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.
Ren X, Pan X, Zhang Z, Wang D, Lu X, Li Y, Wen D, Long H, Luo J, Feng Y, Zhuang X, Zhang F, Liu J, Leng F, Lang X, Bai Y, She M, Tu Z, Pan J, Ding K. Ren X, et al. Among authors: lu x. J Med Chem. 2013 Feb 14;56(3):879-94. doi: 10.1021/jm301581y. Epub 2013 Jan 28. J Med Chem. 2013. PMID: 23301703
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