Reversible heart failure in G alpha(q) transgenic mice.
Jiang YP, Ballou LM, Lu Z, Li Wan, Kelly DJ, Cohen IS, Lin RZ.
Jiang YP, et al. Among authors: lu z.
J Biol Chem. 2006 Oct 6;281(40):29988-92. doi: 10.1074/jbc.M604699200. Epub 2006 Aug 7.
J Biol Chem. 2006.
PMID: 16893886
Free article.
We demonstrated previously that mice expressing a recombinant Galpha(q) protein, the activity of which can be turned on or off at will in cardiac myocytes, develop a dilated cardiomyopathy with generalized edema and heart failure following activation of the protein (Fan, G., Jian …
We demonstrated previously that mice expressing a recombinant Galpha(q) protein, the activity of which can be turned on or off at will in ca …