Lu Z - Search Results

1

Population characteristics of hepatic dihydropyrimidine dehydrogenase activity, a key metabolic enzyme in 5-fluorouracil chemotherapy.

Lu Z, Zhang R, Diasio RB. Lu Z, et al. Clin Pharmacol Ther. 1995 Nov;58(5):512-22. doi: 10.1016/0009-9236(95)90171-X. Clin Pharmacol Ther. 1995. PMID: 7586945

2

Severe neurotoxicity following 5-fluorouracil-based chemotherapy in a patient with dihydropyrimidine dehydrogenase deficiency.

Takimoto CH, Lu ZH, Zhang R, Liang MD, Larson LV, Cantilena LR Jr, Grem JL, Allegra CJ, Diasio RB, Chu E. Takimoto CH, et al. Among authors: lu zh. Clin Cancer Res. 1996 Mar;2(3):477-81. Clin Cancer Res. 1996. PMID: 9816193

3

Purification and characterization of dihydropyrimidine dehydrogenase from human liver.

Lu ZH, Zhang R, Diasio RB. Lu ZH, et al. J Biol Chem. 1992 Aug 25;267(24):17102-9. J Biol Chem. 1992. PMID: 1512248

4

Comparison of dihydropyrimidine dehydrogenase from human, rat, pig and cow liver. Biochemical and immunological properties.

Lu ZH, Zhang R, Diasio RB. Lu ZH, et al. Biochem Pharmacol. 1993 Sep 1;46(5):945-52. doi: 10.1016/0006-2952(93)90505-q. Biochem Pharmacol. 1993. PMID: 8373446

5

Dihydropyrimidine dehydrogenase activity and fluorouracil chemotherapy.

Diasio RB, Lu Z. Diasio RB, et al. Among authors: lu z. J Clin Oncol. 1994 Nov;12(11):2239-42. doi: 10.1200/JCO.1994.12.11.2239. J Clin Oncol. 1994. PMID: 7964937 Review. No abstract available.

6

Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: population characteristics, newly identified deficient patients, and clinical implication in 5-fluorouracil chemotherapy.

Lu Z, Zhang R, Diasio RB. Lu Z, et al. Cancer Res. 1993 Nov 15;53(22):5433-8. Cancer Res. 1993. PMID: 8221682

Using a polyclonal antibody raised against human liver DPD in our laboratory (Z. Lu, R. Zhang, and R. B. Diasio. J. Biol. Chem., 267: 17102-17109, 1992), Western blot analysis demonstrated decreased DPD protein in the liver cytosol from DPD-deficient patients compar …

Using a polyclonal antibody raised against human liver DPD in our laboratory (Z. Lu, R. Zhang, and R. B. Diasio. J. Biol. Chem …

7

Decreased dihydropyrimidine dehydrogenase activity in a population of patients with breast cancer: implication for 5-fluorouracil-based chemotherapy.

Lu Z, Zhang R, Carpenter JT, Diasio RB. Lu Z, et al. Clin Cancer Res. 1998 Feb;4(2):325-9. Clin Cancer Res. 1998. PMID: 9516918 Clinical Trial.

8

Pharmacokinetics and tissue distribution in rats of an oligodeoxynucleotide phosphorothioate (GEM 91) developed as a therapeutic agent for human immunodeficiency virus type-1.

Zhang R, Diasio RB, Lu Z, Liu T, Jiang Z, Galbraith WM, Agrawal S. Zhang R, et al. Among authors: lu z. Biochem Pharmacol. 1995 Mar 30;49(7):929-39. doi: 10.1016/0006-2952(95)00010-w. Biochem Pharmacol. 1995. PMID: 7741765

9

Pharmacokinetics and tissue disposition of a chimeric oligodeoxynucleoside phosphorothioate in rats after intravenous administration.

Zhang R, Iyer RP, Yu D, Tan W, Zhang X, Lu Z, Zhao H, Agrawal S. Zhang R, et al. Among authors: lu z. J Pharmacol Exp Ther. 1996 Aug;278(2):971-9. J Pharmacol Exp Ther. 1996. PMID: 8768755

10

Fluoropyrimidine catabolism.

Diasio RB, Lu Z, Zhang R, Shahinian HS. Diasio RB, et al. Among authors: lu z. Cancer Treat Res. 1995;78:71-93. doi: 10.1007/978-1-4615-2007-8_4. Cancer Treat Res. 1995. PMID: 8595148 Review. No abstract available.

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