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Lupane triterpenes isolated from Vasconcellea chilensis (wild papaya) inhibit colorectal cancer cell growth by targeting the Wnt/β-catenin signaling pathway.
Scaletta F, Formisano C, Madrid A, Montenegro I, Izzo L, Samavat MS, Afra S, Stornaiuolo M, Taglialatela-Scafati O, Sirignano C, Rigano D. Scaletta F, et al. Among authors: izzo l. Fitoterapia. 2026 May 14;192:107294. doi: 10.1016/j.fitote.2026.107294. Online ahead of print. Fitoterapia. 2026. PMID: 42134482 Free article.
In Vitro Influence of a Chemically Characterized Hippophae rhamnoides L. Fruit Extract on Healthy and Constipated Human Gut Microbiota Functionality and Aquaporin-3 Expression.
De Lellis LF, Toledano-Marín Á, Navarro-Moreno M, Caiazzo E, Madonna G, Delgado-Osorio A, Buccato DG, Izzo L, Paolillo A, Di Minno A, Ullah H, Morone MV, De Filippis A, Galdiero M, Ialenti A, Rufián Henares JÁ, Daglia M. De Lellis LF, et al. Among authors: izzo l. Foods. 2025 Nov 6;14(21):3800. doi: 10.3390/foods14213800. Foods. 2025. PMID: 41227770 Free PMC article.
Enhancing Human Health Through Nutrient and Bioactive Compound Recovery from Agri-Food By-Products: A Decade of Progress.
Ingallina C, Spano M, Prencipe SA, Vinci G, Di Sotto A, Ambroselli D, Vergine V, Crestoni ME, Di Meo C, Zoratto N, Izzo L, Navarré A, Adiletta G, Russo P, Di Matteo G, Mannina L, Giusti AM. Ingallina C, et al. Among authors: izzo l. Nutrients. 2025 Jul 31;17(15):2528. doi: 10.3390/nu17152528. Nutrients. 2025. PMID: 40806112 Free PMC article. Review.
Exploring the dual role of Mangifera indica L. in regulating immune response and pain persistence in inflammatory bowel disease.
Lucarini E, Schettino A, Marigliano N, Ciampi C, Smimmo M, Romano F, Paolillo A, Izzo L, Begum J, Mansour AA, Iaccarino N, Randazzo A, Greco KV, Scarpa R, Caso F, Iqbal AJ, Bucci M, Ghelardini C, Di Cesare Mannelli L, Saviano A, Maione F. Lucarini E, et al. Among authors: izzo l. Pharmacol Res. 2025 Jul;217:107773. doi: 10.1016/j.phrs.2025.107773. Epub 2025 May 17. Pharmacol Res. 2025. PMID: 40389041 Free article.
Unveiling the biological effects of DNA G-quadruplex ligands through multi-omics data integration.
Romano F, Persico C, Barra A, Pinto G, Illiano A, Amoresano A, Aiello I, Abate S, D'Auria L, Martello V, D'Agostino N, Giustiniano M, Russo C, Izzo L, Merlino F, Brancaccio D, Pagano B, Amato J, Marzano S, D'Aria F, Amente S, Bro R, Rasmussen MA, Cassese M, Ammendola R, Cattaneo F, De Tito S, Iaccarino N, Di Porzio A, Randazzo A. Romano F, et al. Among authors: izzo l. Int J Biol Macromol. 2025 Jun;313:144325. doi: 10.1016/j.ijbiomac.2025.144325. Epub 2025 May 16. Int J Biol Macromol. 2025. PMID: 40383348 Free article.
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