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Deficient brain RNA polymerase and altered nucleolar structure persists until day 8 after perinatal asphyxia of the rat.
Kastner P, Mosgoeller W, Fang-Kircher S, Kitzmueller E, Kirchner L, Hoeger H, Seither P, Lubec G, Lubec B. Kastner P, et al. Pediatr Res. 2003 Jan;53(1):62-71. doi: 10.1203/00006450-200301000-00013. Pediatr Res. 2003. PMID: 12508083
Perinatal asphyxia in the guinea pig leads to morphologic but not neurologic, cognitive, or behavioral changes.
Hoeger H, Bubna-Littitz H, Engelmann M, Schwerdtner I, Schmid D, Lahoda R, Seidl R, Lubec G, Lubec B. Hoeger H, et al. J Investig Med. 2003 Jul;51(4):233-9. doi: 10.1136/jim-51-04-25. J Investig Med. 2003. PMID: 12929740
Neuronal nitric oxide synthase knock-out mice show impaired cognitive performance.
Weitzdoerfer R, Hoeger H, Engidawork E, Engelmann M, Singewald N, Lubec G, Lubec B. Weitzdoerfer R, et al. Nitric Oxide. 2004 May;10(3):130-40. doi: 10.1016/j.niox.2004.03.007. Nitric Oxide. 2004. PMID: 15158692
Long-term influence of perinatal asphyxia on the social behavior in aging rats.
Weitzdoerfer R, Gerstl N, Pollak D, Hoeger H, Dreher W, Lubec G. Weitzdoerfer R, et al. Gerontology. 2004 Jul-Aug;50(4):200-5. doi: 10.1159/000078348. Gerontology. 2004. PMID: 15258424
Impaired cognitive performance in neuronal nitric oxide synthase knockout mice is associated with hippocampal protein derangements.
Kirchner L, Weitzdoerfer R, Hoeger H, Url A, Schmidt P, Engelmann M, Villar SR, Fountoulakis M, Lubec G, Lubec B. Kirchner L, et al. Nitric Oxide. 2004 Dec;11(4):316-30. doi: 10.1016/j.niox.2004.10.005. Epub 2004 Nov 25. Nitric Oxide. 2004. PMID: 15604044
Proteomic evaluation of hippocampus, the main anatomical structure computing cognitive functions, revealed aberrant expression of a synaptosomal associated protein of the exocytotic machinery (NSF), glycolytic enzymes, chaperones 78 kDa glucose-regulated protein, T-complex protei …
Proteomic evaluation of hippocampus, the main anatomical structure computing cognitive functions, revealed aberrant expression of a synaptos …
Metalloproteinase ADAMTS-1 but not ADAMTS-5 is manifold overexpressed in neurodegenerative disorders as Down syndrome, Alzheimer's and Pick's disease.
Miguel RF, Pollak A, Lubec G. Miguel RF, et al. Brain Res Mol Brain Res. 2005 Jan 5;133(1):1-5. doi: 10.1016/j.molbrainres.2004.09.008. Brain Res Mol Brain Res. 2005. PMID: 15661359
Proteome analysis in hippocampus of mice overexpressing human Cu/Zn-superoxide dismutase 1.
Shin JH, London J, Le Pecheur M, Weitzdoerfer R, Hoeger H, Lubec G. Shin JH, et al. Neurochem Int. 2005 Jun;46(8):641-53. doi: 10.1016/j.neuint.2004.06.017. Epub 2005 Apr 7. Neurochem Int. 2005. PMID: 15863242
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