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Year Number of Results
2003 1
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Page 1
Lubiprostone.
[No authors listed] [No authors listed] 2020 Nov 16. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2020 Nov 16. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000987 Free Books & Documents. Review.
No information is available on the use of lubiprostone during breastfeeding. The manufacturer reports that the drug and its metabolite are undetectable in rat milk and would not be expected to cause any adverse effects in a breastfed infant. ...
No information is available on the use of lubiprostone during breastfeeding. The manufacturer reports that the drug and its metabolit …
Lubiprostone.
[No authors listed] [No authors listed] 2019 Apr 25. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2019 Apr 25. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643332 Free Books & Documents. Review.
Lubiprostone is an activator of chloride channels (ClC-2) in the intestine and is used for treatment of chronic constipation and irritable bowel syndrome. Lubiprostone has not been linked to serum enzyme elevations during treatment or to episodes of clinically appar …
Lubiprostone is an activator of chloride channels (ClC-2) in the intestine and is used for treatment of chronic constipation and irri …
Comparative profiles of lubiprostone, linaclotide, and elobixibat for chronic constipation: a systematic literature review with meta-analysis and number needed to treat/harm.
Rao SS, Manabe N, Karasawa Y, Hasebe Y, Nozawa K, Nakajima A, Fukudo S. Rao SS, et al. BMC Gastroenterol. 2024 Jan 2;24(1):12. doi: 10.1186/s12876-023-03104-8. BMC Gastroenterol. 2024. PMID: 38166671 Free PMC article.
OBJECTIVE: To comprehensively evaluate the efficacy, safety, patient symptoms, and quality-of-life (QoL) of lubiprostone, linaclotide, and elobixibat as treatment for chronic constipation (CC). ...However, the NNH analysis revealed distinct safety profiles: lubiprostone …
OBJECTIVE: To comprehensively evaluate the efficacy, safety, patient symptoms, and quality-of-life (QoL) of lubiprostone, linaclotide …
Lubiprostone in constipation: clinical evidence and place in therapy.
Wilson N, Schey R. Wilson N, et al. Ther Adv Chronic Dis. 2015 Mar;6(2):40-50. doi: 10.1177/2040622314567678. Ther Adv Chronic Dis. 2015. PMID: 25729555 Free PMC article. Review.
The most common side effects associated with lubiprostone are mild to moderate nausea and diarrhea. Currently lubiprostone is approved for treatment of chronic constipation and opioid-induced constipation for men and women at 24 g twice daily and for treatment of ir …
The most common side effects associated with lubiprostone are mild to moderate nausea and diarrhea. Currently lubiprostone is …
Lubiprostone: RU 0211, SPI 0211.
[No authors listed] [No authors listed] Drugs R D. 2005;6(4):245-8. doi: 10.2165/00126839-200506040-00009. Drugs R D. 2005. PMID: 15991886 Review.
Lubiprostone [RU 0211, SPI 0211] is a bicyclic fatty acid that acts as a chloride channel opener, increasing intestinal water secretion. ...Lubiprostone activates a specific chloride channel (CLC2) on cells lining the gut, thereby naturally increasing intestinal flu …
Lubiprostone [RU 0211, SPI 0211] is a bicyclic fatty acid that acts as a chloride channel opener, increasing intestinal water secreti …
Lubiprostone: chloride channel activator for chronic constipation.
Rivkin A, Chagan L. Rivkin A, et al. Clin Ther. 2006 Dec;28(12):2008-21. doi: 10.1016/j.clinthera.2006.12.013. Clin Ther. 2006. PMID: 17296458 Review.
RESULTS: Lubiprostone activates a chloride channel (ie, subtype 2) and increases chloride and fluid secretion into the intestines, resulting in relief of constipation. ...Nausea was the most common adverse effect reported in clinical trials, occurring in 30.9% of patients. …
RESULTS: Lubiprostone activates a chloride channel (ie, subtype 2) and increases chloride and fluid secretion into the intestines, re …
Lubiprostone in the treatment of chronic idiopathic constipation: an update on health-related quality of life and patient-reported outcomes.
Hayat M, Zia H, Nusrat S. Hayat M, et al. Patient Relat Outcome Meas. 2019 Feb 12;10:43-47. doi: 10.2147/PROM.S157905. eCollection 2019. Patient Relat Outcome Meas. 2019. PMID: 30858742 Free PMC article. Review.
Pharmacologic options include fiber supplementation, laxatives, serotonergic agents, and prosecretory agents such as lubiprostone. In this review, we were able to conclude that lubiprostone, when used for chronic idiopathic constipation, has a significantly benefici …
Pharmacologic options include fiber supplementation, laxatives, serotonergic agents, and prosecretory agents such as lubiprostone. In …
Lubiprostone.
Winpenny JP. Winpenny JP. IDrugs. 2005 May;8(5):416-22. IDrugs. 2005. PMID: 15883925 Review.
Lubiprostone for the treatment of opioid-induced bowel dysfunction.
Wong BS, Camilleri M. Wong BS, et al. Expert Opin Pharmacother. 2011 Apr;12(6):983-90. doi: 10.1517/14656566.2011.566559. Epub 2011 Mar 9. Expert Opin Pharmacother. 2011. PMID: 21385112 Review.
EXPERT OPINION: Lubiprostone has potential in treating OBD and deserves additional study. ...Lubiprostone seems safe for long-term use in CIC patients, and a similar safety profile is anticipated in OBD....
EXPERT OPINION: Lubiprostone has potential in treating OBD and deserves additional study. ...Lubiprostone seems safe for long- …
Lubiprostone: a chloride channel activator.
Lacy BE, Levy LC. Lacy BE, et al. J Clin Gastroenterol. 2007 Apr;41(4):345-51. doi: 10.1097/01.mcg.0000225665.68920.df. J Clin Gastroenterol. 2007. PMID: 17413599 Review.
In January 2006 the Food and Drug Administration approved lubiprostone for the treatment of chronic constipation in men and women aged 18 and over. Lubiprostone is categorized as a prostone, a bicyclic fatty acid metabolite of prostaglandin E1. ...
In January 2006 the Food and Drug Administration approved lubiprostone for the treatment of chronic constipation in men and women age …
437 results