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Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB-driven inflammation and cardiovascular risk.
Zannas AS, Jia M, Hafner K, Baumert J, Wiechmann T, Pape JC, Arloth J, Ködel M, Martinelli S, Roitman M, Röh S, Haehle A, Emeny RT, Iurato S, Carrillo-Roa T, Lahti J, Räikkönen K, Eriksson JG, Drake AJ, Waldenberger M, Wahl S, Kunze S, Lucae S, Bradley B, Gieger C, Hausch F, Smith AK, Ressler KJ, Müller-Myhsok B, Ladwig KH, Rein T, Gassen NC, Binder EB. Zannas AS, et al. Among authors: lucae s. Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11370-11379. doi: 10.1073/pnas.1816847116. Epub 2019 May 21. Proc Natl Acad Sci U S A. 2019. PMID: 31113877 Free PMC article.
Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment.
Binder EB, Salyakina D, Lichtner P, Wochnik GM, Ising M, Pütz B, Papiol S, Seaman S, Lucae S, Kohli MA, Nickel T, Künzel HE, Fuchs B, Majer M, Pfennig A, Kern N, Brunner J, Modell S, Baghai T, Deiml T, Zill P, Bondy B, Rupprecht R, Messer T, Köhnlein O, Dabitz H, Brückl T, Müller N, Pfister H, Lieb R, Mueller JC, Lõhmussaar E, Strom TM, Bettecken T, Meitinger T, Uhr M, Rein T, Holsboer F, Muller-Myhsok B. Binder EB, et al. Among authors: lucae s. Nat Genet. 2004 Dec;36(12):1319-25. doi: 10.1038/ng1479. Epub 2004 Nov 21. Nat Genet. 2004. PMID: 15565110
Association of a Met88Val diazepam binding inhibitor (DBI) gene polymorphism and anxiety disorders with panic attacks.
Thoeringer CK, Binder EB, Salyakina D, Erhardt A, Ising M, Unschuld PG, Kern N, Lucae S, Brueckl TM, Mueller MB, Fuchs B, Puetz B, Lieb R, Uhr M, Holsboer F, Mueller-Myhsok B, Keck ME. Thoeringer CK, et al. Among authors: lucae s. J Psychiatr Res. 2007 Oct;41(7):579-84. doi: 10.1016/j.jpsychires.2006.06.001. Epub 2006 Aug 14. J Psychiatr Res. 2007. PMID: 16904689
Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism.
Baghai TC, Binder EB, Schule C, Salyakina D, Eser D, Lucae S, Zwanzger P, Haberger C, Zill P, Ising M, Deiml T, Uhr M, Illig T, Wichmann HE, Modell S, Nothdurfter C, Holsboer F, Müller-Myhsok B, Möller HJ, Rupprecht R, Bondy B. Baghai TC, et al. Among authors: lucae s. Mol Psychiatry. 2006 Nov;11(11):1003-15. doi: 10.1038/sj.mp.4001884. Epub 2006 Aug 22. Mol Psychiatry. 2006. PMID: 16924268
Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders.
Erhardt A, Lucae S, Unschuld PG, Ising M, Kern N, Salyakina D, Lieb R, Uhr M, Binder EB, Keck ME, Müller-Myhsok B, Holsboer F. Erhardt A, et al. Among authors: lucae s. J Affect Disord. 2007 Aug;101(1-3):159-68. doi: 10.1016/j.jad.2006.11.016. Epub 2007 Jan 2. J Affect Disord. 2007. PMID: 17197037
Polymorphisms in the serotonin receptor gene HTR2A are associated with quantitative traits in panic disorder.
Unschuld PG, Ising M, Erhardt A, Lucae S, Kloiber S, Kohli M, Salyakina D, Welt T, Kern N, Lieb R, Uhr M, Binder EB, Müller-Myhsok B, Holsboer F, Keck ME. Unschuld PG, et al. Among authors: lucae s. Am J Med Genet B Neuropsychiatr Genet. 2007 Jun 5;144B(4):424-9. doi: 10.1002/ajmg.b.30412. Am J Med Genet B Neuropsychiatr Genet. 2007. PMID: 17440930
175 results