Lucas CD - Search Results

1

Downregulation of Mcl-1 has anti-inflammatory pro-resolution effects and enhances bacterial clearance from the lung.

Lucas CD, Dorward DA, Tait MA, Fox S, Marwick JA, Allen KC, Robb CT, Hirani N, Haslett C, Duffin R, Rossi AG. Lucas CD, et al. Mucosal Immunol. 2014 Jul;7(4):857-68. doi: 10.1038/mi.2013.102. Epub 2013 Nov 27. Mucosal Immunol. 2014. PMID: 24280938 Free PMC article.

2

Expression of V1A and GRP receptors leads to cellular transformation and increased sensitivity to substance-P analogue-induced growth inhibition.

MacKinnon AC, Tufail-Hanif U, Lucas CD, Jodrell D, Haslett C, Sethi T. MacKinnon AC, et al. Among authors: lucas cd. Br J Cancer. 2005 Feb 14;92(3):522-31. doi: 10.1038/sj.bjc.6602366. Br J Cancer. 2005. PMID: 15685238 Free PMC article.

3

Induction of eosinophil apoptosis by the cyclin-dependent kinase inhibitor AT7519 promotes the resolution of eosinophil-dominant allergic inflammation.

Alessandri AL, Duffin R, Leitch AE, Lucas CD, Sheldrake TA, Dorward DA, Hirani N, Pinho V, de Sousa LP, Teixeira MM, Lyons JF, Haslett C, Rossi AG. Alessandri AL, et al. Among authors: lucas cd. PLoS One. 2011;6(9):e25683. doi: 10.1371/journal.pone.0025683. Epub 2011 Sep 30. PLoS One. 2011. PMID: 21984938 Free PMC article.

4

Editorial: Neutrophil apoptosis: hot on the TRAIL of inflammatory resolution.

Leitch AE, Lucas CD, Rossi AG. Leitch AE, et al. Among authors: lucas cd. J Leukoc Biol. 2011 Nov;90(5):841-3. doi: 10.1189/jlb.0511222. J Leukoc Biol. 2011. PMID: 22045921 No abstract available.

5

Imaging inflammation: molecular strategies to visualize key components of the inflammatory cascade, from initiation to resolution.

Dorward DA, Lucas CD, Rossi AG, Haslett C, Dhaliwal K. Dorward DA, et al. Among authors: lucas cd. Pharmacol Ther. 2012 Aug;135(2):182-99. doi: 10.1016/j.pharmthera.2012.05.006. Epub 2012 May 22. Pharmacol Ther. 2012. PMID: 22627270 Review.

6

Cyclin-dependent kinases 7 and 9 specifically regulate neutrophil transcription and their inhibition drives apoptosis to promote resolution of inflammation.

Leitch AE, Lucas CD, Marwick JA, Duffin R, Haslett C, Rossi AG. Leitch AE, et al. Among authors: lucas cd. Cell Death Differ. 2012 Dec;19(12):1950-61. doi: 10.1038/cdd.2012.80. Epub 2012 Jun 29. Cell Death Differ. 2012. PMID: 22743999 Free PMC article.

7

Flavones induce neutrophil apoptosis by down-regulation of Mcl-1 via a proteasomal-dependent pathway.

Lucas CD, Allen KC, Dorward DA, Hoodless LJ, Melrose LA, Marwick JA, Tucker CS, Haslett C, Duffin R, Rossi AG. Lucas CD, et al. FASEB J. 2013 Mar;27(3):1084-94. doi: 10.1096/fj.12-218990. Epub 2012 Nov 29. FASEB J. 2013. PMID: 23195034 Free PMC article. Clinical Trial.

8

Novel R-roscovitine NO-donor hybrid compounds as potential pro-resolution of inflammation agents.

Montanaro G, Bertinaria M, Rolando B, Fruttero R, Lucas CD, Dorward DA, Rossi AG, Megson IL, Gasco A. Montanaro G, et al. Among authors: lucas cd. Bioorg Med Chem. 2013 Apr 1;21(7):2107-16. doi: 10.1016/j.bmc.2013.01.009. Epub 2013 Jan 16. Bioorg Med Chem. 2013. PMID: 23394865 Free PMC article.

9

Activation of conventional protein kinase C (PKC) is critical in the generation of human neutrophil extracellular traps.

Gray RD, Lucas CD, MacKellar A, Li F, Hiersemenzel K, Haslett C, Davidson DJ, Rossi AG. Gray RD, et al. Among authors: lucas cd. J Inflamm (Lond). 2013 Mar 21;10(1):12. doi: 10.1186/1476-9255-10-12. J Inflamm (Lond). 2013. PMID: 23514610 Free PMC article.

10

Resolution of inflammation: mechanisms and opportunity for drug development.

Alessandri AL, Sousa LP, Lucas CD, Rossi AG, Pinho V, Teixeira MM. Alessandri AL, et al. Among authors: lucas cd. Pharmacol Ther. 2013 Aug;139(2):189-212. doi: 10.1016/j.pharmthera.2013.04.006. Epub 2013 Apr 11. Pharmacol Ther. 2013. PMID: 23583354 Review.

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