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53BP1 fosters fidelity of homology-directed DNA repair.
Ochs F, Somyajit K, Altmeyer M, Rask MB, Lukas J, Lukas C. Ochs F, et al. Among authors: lukas j, lukas c. Nat Struct Mol Biol. 2016 Aug;23(8):714-21. doi: 10.1038/nsmb.3251. Epub 2016 Jun 27. Nat Struct Mol Biol. 2016. PMID: 27348077
LEDGF (p75) promotes DNA-end resection and homologous recombination.
Daugaard M, Baude A, Fugger K, Povlsen LK, Beck H, Sørensen CS, Petersen NH, Sorensen PH, Lukas C, Bartek J, Lukas J, Rohde M, Jäättelä M. Daugaard M, et al. Among authors: lukas j, lukas c. Nat Struct Mol Biol. 2012 Aug;19(8):803-10. doi: 10.1038/nsmb.2314. Epub 2012 Jul 8. Nat Struct Mol Biol. 2012. PMID: 22773103
The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage.
Larsen DH, Hari F, Clapperton JA, Gwerder M, Gutsche K, Altmeyer M, Jungmichel S, Toledo LI, Fink D, Rask MB, Grøfte M, Lukas C, Nielsen ML, Smerdon SJ, Lukas J, Stucki M. Larsen DH, et al. Among authors: lukas j, lukas c. Nat Cell Biol. 2014 Aug;16(8):792-803. doi: 10.1038/ncb3007. Epub 2014 Jul 27. Nat Cell Biol. 2014. PMID: 25064736 Free PMC article.
Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks.
Sotiriou SK, Kamileri I, Lugli N, Evangelou K, Da-Ré C, Huber F, Padayachy L, Tardy S, Nicati NL, Barriot S, Ochs F, Lukas C, Lukas J, Gorgoulis VG, Scapozza L, Halazonetis TD. Sotiriou SK, et al. Among authors: lukas j, lukas c. Mol Cell. 2016 Dec 15;64(6):1127-1134. doi: 10.1016/j.molcel.2016.10.038. Mol Cell. 2016. PMID: 27984746 Free PMC article.
Stabilization of chromatin topology safeguards genome integrity.
Ochs F, Karemore G, Miron E, Brown J, Sedlackova H, Rask MB, Lampe M, Buckle V, Schermelleh L, Lukas J, Lukas C. Ochs F, et al. Among authors: lukas j, lukas c. Nature. 2019 Oct;574(7779):571-574. doi: 10.1038/s41586-019-1659-4. Epub 2019 Oct 23. Nature. 2019. PMID: 31645724
510 results