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Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling.
Betts JC, Lukey PT, Robb LC, McAdam RA, Duncan K. Betts JC, et al. Among authors: lukey pt. Mol Microbiol. 2002 Feb;43(3):717-31. doi: 10.1046/j.1365-2958.2002.02779.x. Mol Microbiol. 2002. PMID: 11929527
Gene-expression patterns in whole blood identify subjects at risk for recurrent tuberculosis.
Mistry R, Cliff JM, Clayton CL, Beyers N, Mohamed YS, Wilson PA, Dockrell HM, Wallace DM, van Helden PD, Duncan K, Lukey PT. Mistry R, et al. Among authors: lukey pt. J Infect Dis. 2007 Feb 1;195(3):357-65. doi: 10.1086/510397. Epub 2006 Dec 21. J Infect Dis. 2007. PMID: 17205474
Signature gene expression profiles discriminate between isoniazid-, thiolactomycin-, and triclosan-treated Mycobacterium tuberculosis.
Betts JC, McLaren A, Lennon MG, Kelly FM, Lukey PT, Blakemore SJ, Duncan K. Betts JC, et al. Among authors: lukey pt. Antimicrob Agents Chemother. 2003 Sep;47(9):2903-13. doi: 10.1128/aac.47.9.2903-2913.2003. Antimicrob Agents Chemother. 2003. PMID: 12936993 Free PMC article.
Characterization of a Mycobacterium tuberculosis H37Rv transposon library reveals insertions in 351 ORFs and mutants with altered virulence.
McAdam RA, Quan S, Smith DA, Bardarov S, Betts JC, Cook FC, Hooker EU, Lewis AP, Woollard P, Everett MJ, Lukey PT, Bancroft GJ, Jacobs WR Jr, Duncan K. McAdam RA, et al. Among authors: lukey pt. Microbiology (Reading). 2002 Oct;148(Pt 10):2975-2986. doi: 10.1099/00221287-148-10-2975. Microbiology (Reading). 2002. PMID: 12368431
Distinct phases of blood gene expression pattern through tuberculosis treatment reflect modulation of the humoral immune response.
Cliff JM, Lee JS, Constantinou N, Cho JE, Clark TG, Ronacher K, King EC, Lukey PT, Duncan K, Van Helden PD, Walzl G, Dockrell HM. Cliff JM, et al. Among authors: lukey pt. J Infect Dis. 2013 Jan 1;207(1):18-29. doi: 10.1093/infdis/jis499. Epub 2012 Aug 7. J Infect Dis. 2013. PMID: 22872737
Protein expression in Mycobacterium tuberculosis differs with growth stage and strain type.
Pheiffer C, Betts J, Lukey P, van Helden P. Pheiffer C, et al. Among authors: lukey p. Clin Chem Lab Med. 2002 Sep;40(9):869-75. doi: 10.1515/CCLM.2002.154. Clin Chem Lab Med. 2002. PMID: 12435102
In situ detection of Mycobacterium tuberculosis transcripts in human lung granulomas reveals differential gene expression in necrotic lesions.
Fenhalls G, Stevens L, Moses L, Bezuidenhout J, Betts JC, Helden Pv Pv, Lukey PT, Duncan K. Fenhalls G, et al. Among authors: lukey pt. Infect Immun. 2002 Nov;70(11):6330-8. doi: 10.1128/iai.70.11.6330-6338.2002. Infect Immun. 2002. PMID: 12379712 Free PMC article.
Protein expression by a Beijing strain differs from that of another clinical isolate and Mycobacterium tuberculosis H37Rv.
Pheiffer C, Betts JC, Flynn HR, Lukey PT, van Helden P. Pheiffer C, et al. Among authors: lukey pt. Microbiology (Reading). 2005 Apr;151(Pt 4):1139-1150. doi: 10.1099/mic.0.27518-0. Microbiology (Reading). 2005. PMID: 15817781
Differential gene expression identifies novel markers of CD4+ and CD8+ T cell activation following stimulation by Mycobacterium tuberculosis.
Cliff JM, Andrade IN, Mistry R, Clayton CL, Lennon MG, Lewis AP, Duncan K, Lukey PT, Dockrell HM. Cliff JM, et al. Among authors: lukey pt. J Immunol. 2004 Jul 1;173(1):485-93. doi: 10.4049/jimmunol.173.1.485. J Immunol. 2004. PMID: 15210809
17 macrophage virulence assays.
Lukey PT, Hooker EU. Lukey PT, et al. Methods Mol Med. 2001;54:271-80. doi: 10.1385/1-59259-147-7:271. Methods Mol Med. 2001. PMID: 21341081
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