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Page 1
Liver gene expression and its rewiring in hepatic steatosis are controlled by PI3Kα-dependent hepatocyte signaling.
Régnier M, Polizzi A, Fougeray T, Fougerat A, Perrier P, Anderson K, Lippi Y, Smati S, Lukowicz C, Lasserre F, Fouche E, Huillet M, Rives C, Tramunt B, Naylies C, Garcia G, Rousseau-Bacquié E, Bertrand-Michel J, Canlet C, Chevolleau-Mege S, Debrauwer L, Heymes C, Burcelin R, Levade T, Gourdy P, Wahli W, Blum Y, Gamet-Payrastre L, Ellero-Simatos S, Guillermet-Guibert J, Hawkins P, Stephens L, Postic C, Montagner A, Loiseau N, Guillou H. Régnier M, et al. Among authors: lukowicz c. PLoS Biol. 2025 Apr 14;23(4):e3003112. doi: 10.1371/journal.pbio.3003112. eCollection 2025 Apr. PLoS Biol. 2025. PMID: 40228209 Free PMC article.
Obesity promotes fumonisin B1 hepatotoxicity.
Dopavogui L, Régnier M, Polizzi A, Ponchon Q, Smati S, Klement W, Lasserre F, Lukowicz C, Lippi Y, Fougerat A, Bertrand-Michel J, Naylies C, Canlet C, Debrauwer L, Rousseau-Bacquié E, Gamet-Payrastre L, Dauriat C, Casas J, Croubels S, De Baere S, Burger HM, Chassaing B, Ellero-Simatos S, Guillou H, Oswald IP, Loiseau N. Dopavogui L, et al. Among authors: lukowicz c. Sci Total Environ. 2023 Sep 15;891:164436. doi: 10.1016/j.scitotenv.2023.164436. Epub 2023 May 27. Sci Total Environ. 2023. PMID: 37247733 Free article.
Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target.
Smati S, Polizzi A, Fougerat A, Ellero-Simatos S, Blum Y, Lippi Y, Régnier M, Laroyenne A, Huillet M, Arif M, Zhang C, Lasserre F, Marrot A, Al Saati T, Wan J, Sommer C, Naylies C, Batut A, Lukowicz C, Fougeray T, Tramunt B, Dubot P, Smith L, Bertrand-Michel J, Hennuyer N, Pradere JP, Staels B, Burcelin R, Lenfant F, Arnal JF, Levade T, Gamet-Payrastre L, Lagarrigue S, Loiseau N, Lotersztajn S, Postic C, Wahli W, Bureau C, Guillaume M, Mardinoglu A, Montagner A, Gourdy P, Guillou H. Smati S, et al. Among authors: lukowicz c. Gut. 2022 Apr;71(4):807-821. doi: 10.1136/gutjnl-2020-323323. Epub 2021 Apr 26. Gut. 2022. PMID: 33903148 Free article.
The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice.
Barretto SA, Lasserre F, Huillet M, Régnier M, Polizzi A, Lippi Y, Fougerat A, Person E, Bruel S, Bétoulières C, Naylies C, Lukowicz C, Smati S, Guzylack L, Olier M, Théodorou V, Mselli-Lakhal L, Zalko D, Wahli W, Loiseau N, Gamet-Payrastre L, Guillou H, Ellero-Simatos S. Barretto SA, et al. Among authors: lukowicz c. Microbiome. 2021 Apr 20;9(1):93. doi: 10.1186/s40168-021-01050-9. Microbiome. 2021. PMID: 33879258 Free PMC article.
Perinatal exposure to a dietary pesticide cocktail does not increase susceptibility to high-fat diet-induced metabolic perturbations at adulthood but modifies urinary and fecal metabolic fingerprints in C57Bl6/J mice.
Smith L, Klément W, Dopavogui L, de Bock F, Lasserre F, Barretto S, Lukowicz C, Fougerat A, Polizzi A, Schaal B, Patris B, Denis C, Feuillet G, Canlet C, Jamin EL, Debrauwer L, Mselli-Lakhal L, Loiseau N, Guillou H, Marchi N, Ellero-Simatos S, Gamet-Payrastre L. Smith L, et al. Among authors: lukowicz c. Environ Int. 2020 Nov;144:106010. doi: 10.1016/j.envint.2020.106010. Epub 2020 Jul 31. Environ Int. 2020. PMID: 32745781 Free article.
Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity.
Régnier M, Polizzi A, Smati S, Lukowicz C, Fougerat A, Lippi Y, Fouché E, Lasserre F, Naylies C, Bétoulières C, Barquissau V, Mouisel E, Bertrand-Michel J, Batut A, Saati TA, Canlet C, Tremblay-Franco M, Ellero-Simatos S, Langin D, Postic C, Wahli W, Loiseau N, Guillou H, Montagner A. Régnier M, et al. Among authors: lukowicz c. Sci Rep. 2020 Apr 16;10(1):6489. doi: 10.1038/s41598-020-63579-3. Sci Rep. 2020. PMID: 32300166 Free PMC article.
Author Correction: Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor.
Lukowicz C, Ellero-Simatos S, Régnier M, Oliviero F, Lasserre F, Polizzi A, Montagner A, Smati S, Boudou F, Lenfant F, Guzylack-Pirou L, Menard S, Barretto S, Fougerat A, Lippi Y, Naylies C, Bertrand-Michel J, Belgnaoui AA, Theodorou V, Marchi N, Gourdy P, Gamet-Payrastre L, Loiseau N, Guillou H, Mselli-Lakhal L. Lukowicz C, et al. Sci Rep. 2020 Mar 3;10(1):4256. doi: 10.1038/s41598-020-61226-5. Sci Rep. 2020. PMID: 32123278 Free PMC article.
Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor.
Lukowicz C, Ellero-Simatos S, Régnier M, Oliviero F, Lasserre F, Polizzi A, Montagner A, Smati S, Boudou F, Lenfant F, Guzylack-Pirou L, Menard S, Barretto S, Fougerat A, Lippi Y, Naylies C, Bertrand-Michel J, Belgnaoui AA, Theodorou V, Marchi N, Gourdy P, Gamet-Payrastre L, Loiseau N, Guillou H, Mselli-Lakhal L. Lukowicz C, et al. Sci Rep. 2019 Dec 27;9(1):20169. doi: 10.1038/s41598-019-56570-0. Sci Rep. 2019. PMID: 31882815 Free PMC article.
18 results