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Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody response.
Her Z, Teng TS, Tan JJ, Teo TH, Kam YW, Lum FM, Lee WW, Gabriel C, Melchiotti R, Andiappan AK, Lulla V, Lulla A, Win MK, Chow A, Biswas SK, Leo YS, Lecuit M, Merits A, Rénia L, Ng LF. Her Z, et al. Among authors: lum fm. EMBO Mol Med. 2015 Jan;7(1):24-41. doi: 10.15252/emmm.201404459. EMBO Mol Med. 2015. PMID: 25452586 Free PMC article.
Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein.
Kam YW, Lum FM, Teo TH, Lee WW, Simarmata D, Harjanto S, Chua CL, Chan YF, Wee JK, Chow A, Lin RT, Leo YS, Le Grand R, Sam IC, Tong JC, Roques P, Wiesmüller KH, Rénia L, Rötzschke O, Ng LF. Kam YW, et al. Among authors: lum fm. EMBO Mol Med. 2012 Apr;4(4):330-43. doi: 10.1002/emmm.201200213. Epub 2012 Mar 5. EMBO Mol Med. 2012. PMID: 22389221 Free PMC article.
Viperin restricts chikungunya virus replication and pathology.
Teng TS, Foo SS, Simamarta D, Lum FM, Teo TH, Lulla A, Yeo NK, Koh EG, Chow A, Leo YS, Merits A, Chin KC, Ng LF. Teng TS, et al. Among authors: lum fm. J Clin Invest. 2012 Dec;122(12):4447-60. doi: 10.1172/JCI63120. Epub 2012 Nov 19. J Clin Invest. 2012. PMID: 23160199 Free PMC article.
Prime-boost immunization strategies against Chikungunya virus.
Hallengärd D, Lum FM, Kümmerer BM, Lulla A, Lulla V, García-Arriaza J, Fazakerley JK, Roques P, Le Grand R, Merits A, Ng LF, Esteban M, Liljeström P. Hallengärd D, et al. Among authors: lum fm. J Virol. 2014 Nov;88(22):13333-43. doi: 10.1128/JVI.01926-14. Epub 2014 Sep 10. J Virol. 2014. PMID: 25210177 Free PMC article.
37 results