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The p75 neurotrophin receptor is a central regulator of glioma invasion.
Johnston AL, Lun X, Rahn JJ, Liacini A, Wang L, Hamilton MG, Parney IF, Hempstead BL, Robbins SM, Forsyth PA, Senger DL. Johnston AL, et al. Among authors: Lun X. Version 2. PLoS Biol. 2007 Aug;5(8):e212. doi: 10.1371/journal.pbio.0050212. PLoS Biol. 2007. PMID: 17696644 Free PMC article.
Efficacy and safety evaluation of human reovirus type 3 in immunocompetent animals: racine and nonhuman primates.
Yang WQ, Lun X, Palmer CA, Wilcox ME, Muzik H, Shi ZQ, Dyck R, Coffey M, Thompson B, Hamilton M, Nishikawa SG, Brasher PM, Fonseca K, George D, Rewcastle NB, Johnston RN, Stewart D, Lee PW, Senger DL, Forsyth PA. Yang WQ, et al. Among authors: Lun X. Clin Cancer Res. 2004 Dec 15;10(24):8561-76. doi: 10.1158/1078-0432.CCR-04-0940. Clin Cancer Res. 2004. PMID: 15623640
Proteolytic disassembly is a critical determinant for reovirus oncolysis.
Alain T, Kim TS, Lun X, Liacini A, Schiff LA, Senger DL, Forsyth PA. Alain T, et al. Among authors: Lun X. Mol Ther. 2007 Aug;15(8):1512-21. doi: 10.1038/sj.mt.6300207. Epub 2007 May 22. Mol Ther. 2007. PMID: 17519890
Efficacy of systemically administered oncolytic vaccinia virotherapy for malignant gliomas is enhanced by combination therapy with rapamycin or cyclophosphamide.
Lun XQ, Jang JH, Tang N, Deng H, Head R, Bell JC, Stojdl DF, Nutt CL, Senger DL, Forsyth PA, McCart JA. Lun XQ, et al. Clin Cancer Res. 2009 Apr 15;15(8):2777-88. doi: 10.1158/1078-0432.CCR-08-2342. Epub 2009 Apr 7. Clin Cancer Res. 2009. PMID: 19351762
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