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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1940 1
1944 1
1946 2
1947 3
1948 2
1949 2
1950 1
1951 2
1952 4
1953 4
1954 3
1955 1
1956 4
1957 3
1958 11
1959 5
1960 10
1961 21
1962 20
1963 73
1964 186
1965 200
1966 201
1967 261
1968 384
1969 480
1970 503
1971 657
1972 812
1973 1147
1974 1235
1975 1362
1976 1329
1977 1299
1978 1268
1979 1390
1980 1492
1981 1517
1982 1417
1983 1509
1984 1664
1985 1652
1986 1563
1987 1599
1988 1567
1989 1540
1990 1570
1991 1487
1992 1388
1993 1423
1994 1246
1995 1172
1996 1084
1997 1122
1998 1054
1999 1034
2000 1109
2001 1084
2002 996
2003 1012
2004 1052
2005 1102
2006 1117
2007 1035
2008 1094
2009 1111
2010 929
2011 961
2012 1080
2013 1070
2014 1071
2015 1079
2016 1056
2017 1117
2018 1146
2019 1010
2020 1213
2021 1214
2022 1136
2023 1120
2024 1158
2025 1231
2026 408

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66,297 results

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Page 1
Temporal trends in serum testosterone and luteinizing hormone levels indicate an ongoing resetting of hypothalamic-pituitary-gonadal function in healthy men: a systematic review.
Santi D, Spaggiari G, Furini C, Griseta V, Zizzi EA, Granata ARM, Simoni M. Santi D, et al. J Endocrinol Invest. 2025 Nov;48(11):2721-2734. doi: 10.1007/s40618-025-02671-9. Epub 2025 Aug 1. J Endocrinol Invest. 2025. PMID: 40748419 Free PMC article.

Exclusion criteria were: (i) age < 18 years old, (ii) conditions affecting testosterone levels, (iii) subjects' enrolment based on testosterone serum levels and (iv) blood examinations performed in a time-frame interval > 10 years. Secondary endpoints: luteinising

…

Exclusion criteria were: (i) age < 18 years old, (ii) conditions affecting testosterone levels, (iii) subjects' enrolment based on testos

…
Ganirelix.
Gillies PS, Faulds D, Balfour JA, Perry CM. Gillies PS, et al. Drugs. 2000 Jan;59(1):107-11; discussion 112-3. doi: 10.2165/00003495-200059010-00007. Drugs. 2000. PMID: 10718102 Review.
Ganirelix is a synthetic third generation gonadotropin-releasing hormone (GnRH) antagonist that is administered via the subcutaneous route. The drug competitively blocks GnRH receptors in the anterior pituitary gland, preventing endogenous GnRH from inducing luteinising …
Ganirelix is a synthetic third generation gonadotropin-releasing hormone (GnRH) antagonist that is administered via the subcutaneous …
Linzagolix: First Approval.
Keam SJ. Keam SJ. Drugs. 2022 Aug;82(12):1317-1325. doi: 10.1007/s40265-022-01753-9. Drugs. 2022. PMID: 35997940 Free PMC article. Review.
Linzagolix (Yselty( )) is an orally administered, selective, non-peptide small molecule gonadotrophin releasing hormone (GnRH) receptor antagonist that is being developed by Kissei Pharmaceutical for the treatment of uterine fibroids and endometriosis in women of reproduct …
Linzagolix (Yselty( )) is an orally administered, selective, non-peptide small molecule gonadotrophin releasing hormone (GnRH) recept …
Screening for central precocious puberty by single basal Luteinizing Hormone levels.
Li Pomi A, Scalini P, De Masi S, Corica D, Pepe G, Wasniewska M, Stagi S. Li Pomi A, et al. Endocrine. 2024 Aug;85(2):955-963. doi: 10.1007/s12020-024-03781-9. Epub 2024 Mar 20. Endocrine. 2024. PMID: 38507183 Free PMC article.
METHODS: 248 girls referred for suspected precocious/early puberty who had undergone a GnRH stimulation test were enrolled and divided into three groups: Premature Idiopathic Thelarche (PIT), CPP, and Early Puberty (EA). For every patient basal serum Luteinising Hormone …
METHODS: 248 girls referred for suspected precocious/early puberty who had undergone a GnRH stimulation test were enrolled and divided into …
Neuroendocrine mechanisms responsible for elevated gonadotrophin-releasing hormone and luteinising hormone pulses in polycystic ovary syndrome.
Moore AM. Moore AM. J Neuroendocrinol. 2025 Aug;37(8):e70028. doi: 10.1111/jne.70028. Epub 2025 Apr 18. J Neuroendocrinol. 2025. PMID: 40251138 Free PMC article. Review.
Specifically, cells in the hypothalamus have a diminished ability to transmit negative feedback signals from gonadal sex steroid hormones to gonadotropin-releasing hormone (GnRH) neurons. This results in an elevated frequency of pulsatile hypothalamic GnRH and pituitary …
Specifically, cells in the hypothalamus have a diminished ability to transmit negative feedback signals from gonadal sex steroid hormones to …
Ovulation: A cellular symphony in three movements.
Thomas C. Thomas C. Semin Cell Dev Biol. 2025 Oct;174:103634. doi: 10.1016/j.semcdb.2025.103634. Epub 2025 Jul 12. Semin Cell Dev Biol. 2025. PMID: 40652787 Free article. Review.
Ovulation is triggered by external hormonal cues: rising levels of follicle-stimulating hormone (FSH), followed by a surge in luteinising hormone (LH) from the anterior pituitary. ...
Ovulation is triggered by external hormonal cues: rising levels of follicle-stimulating hormone (FSH), followed by a surge in lute …
A review of luteinising hormone and human chorionic gonadotropin when used in assisted reproductive technology.
Ezcurra D, Humaidan P. Ezcurra D, et al. Reprod Biol Endocrinol. 2014 Oct 3;12:95. doi: 10.1186/1477-7827-12-95. Reprod Biol Endocrinol. 2014. PMID: 25280580 Free PMC article. Review.
Products, such as human menopausal gonadotropin (hMG), consist not only of a mixture of the hormones, follicle-stimulating hormone (FSH), luteinising hormone (LH) and human chorionic gonadotropin (hCG), but also other biologically active contaminants, such as …
Products, such as human menopausal gonadotropin (hMG), consist not only of a mixture of the hormones, follicle-stimulating hormone (F …
New methods to investigate the GnRH pulse generator.
Ivanova D, O'Byrne KT. Ivanova D, et al. J Mol Endocrinol. 2024 Jan 11;72(2):e230079. doi: 10.1530/JME-23-0079. Print 2024 Feb 1. J Mol Endocrinol. 2024. PMID: 38085702 Free PMC article. Review.
The exact neural construct underlying the dynamic secretion of gonadotrophin-releasing hormone (GnRH) has only recently been identified despite the detection of multiunit electrical activity volleys associated with pulsatile luteinising hormone (LH) secretion …
The exact neural construct underlying the dynamic secretion of gonadotrophin-releasing hormone (GnRH) has only recently been identifi …
Kisspeptin-neuron control of LH pulsatility and ovulation.
Stevenson H, Bartram S, Charalambides MM, Murthy S, Petitt T, Pradeep A, Vineall O, Abaraonye I, Lancaster A, Koysombat K, Patel B, Abbara A. Stevenson H, et al. Front Endocrinol (Lausanne). 2022 Nov 21;13:951938. doi: 10.3389/fendo.2022.951938. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36479214 Free PMC article. Review.
Feedback from oestradiol (E2) plays a critical role in the regulation of major events in the physiological menstrual cycle including the release of gonadotrophins to stimulate follicular growth, and the mid-cycle luteinising hormone (LH) surge that leads to ovulatio …
Feedback from oestradiol (E2) plays a critical role in the regulation of major events in the physiological menstrual cycle including the rel …
66,297 results
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