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Tissue factor in the heart. Multiple roles in hemostasis, thrombosis, and inflammation.
Luther T, Mackman N. Luther T, et al. Trends Cardiovasc Med. 2001 Nov;11(8):307-12. doi: 10.1016/s1050-1738(01)00129-3. Trends Cardiovasc Med. 2001. PMID: 11728878 Review.
Inhibition of the tissue factor-thrombin pathway limits infarct size after myocardial ischemia-reperfusion injury by reducing inflammation.
Erlich JH, Boyle EM, Labriola J, Kovacich JC, Santucci RA, Fearns C, Morgan EN, Yun W, Luther T, Kojikawa O, Martin TR, Pohlman TH, Verrier ED, Mackman N. Erlich JH, et al. Among authors: luther t. Am J Pathol. 2000 Dec;157(6):1849-62. doi: 10.1016/S0002-9440(10)64824-9. Am J Pathol. 2000. PMID: 11106558 Free PMC article.
Intravascular tissue factor pathway--a model for rapid initiation of coagulation within the blood vessel.
Engelmann B, Luther T, Müller I. Engelmann B, et al. Among authors: luther t. Thromb Haemost. 2003 Jan;89(1):3-8. Thromb Haemost. 2003. PMID: 12540946 Review.
Protease-activated receptor-1 contributes to cardiac remodeling and hypertrophy.
Pawlinski R, Tencati M, Hampton CR, Shishido T, Bullard TA, Casey LM, Andrade-Gordon P, Kotzsch M, Spring D, Luther T, Abe J, Pohlman TH, Verrier ED, Blaxall BC, Mackman N. Pawlinski R, et al. Among authors: luther t. Circulation. 2007 Nov 13;116(20):2298-306. doi: 10.1161/CIRCULATIONAHA.107.692764. Epub 2007 Oct 29. Circulation. 2007. PMID: 17967980 Free PMC article.
Tissue factor is required for uterine hemostasis and maintenance of the placental labyrinth during gestation.
Erlich J, Parry GC, Fearns C, Muller M, Carmeliet P, Luther T, Mackman N. Erlich J, et al. Among authors: luther t. Proc Natl Acad Sci U S A. 1999 Jul 6;96(14):8138-43. doi: 10.1073/pnas.96.14.8138. Proc Natl Acad Sci U S A. 1999. PMID: 10393961 Free PMC article.
Low levels of tissue factor are compatible with development and hemostasis in mice.
Parry GC, Erlich JH, Carmeliet P, Luther T, Mackman N. Parry GC, et al. Among authors: luther t. J Clin Invest. 1998 Feb 1;101(3):560-9. doi: 10.1172/JCI814. J Clin Invest. 1998. PMID: 9449688 Free PMC article.
Tissue factor deficiency causes cardiac fibrosis and left ventricular dysfunction.
Pawlinski R, Fernandes A, Kehrle B, Pedersen B, Parry G, Erlich J, Pyo R, Gutstein D, Zhang J, Castellino F, Melis E, Carmeliet P, Baretton G, Luther T, Taubman M, Rosen E, Mackman N. Pawlinski R, et al. Among authors: luther t. Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15333-8. doi: 10.1073/pnas.242501899. Epub 2002 Nov 8. Proc Natl Acad Sci U S A. 2002. PMID: 12426405 Free PMC article.
Role of tissue factor in adhesion of mononuclear phagocytes to and trafficking through endothelium in vitro.
Randolph GJ, Luther T, Albrecht S, Magdolen V, Muller WA. Randolph GJ, et al. Among authors: luther t. Blood. 1998 Dec 1;92(11):4167-77. Blood. 1998. PMID: 9834221
Functional implications of tissue factor localization to cell-cell contacts in myocardium.
Luther T, Dittert DD, Kotzsch M, Erlich J, Albrecht S, Mackman N, Müller M. Luther T, et al. J Pathol. 2000 Sep;192(1):121-30. doi: 10.1002/1096-9896(2000)9999:9999<::AID-PATH667>3.0.CO;2-I. J Pathol. 2000. PMID: 10951409
Immunological and functional analyses of the extracellular domain of human tissue factor.
Magdolen V, Albrecht S, Kotzsch M, Haller C, Bürgle M, Jacob U, Grosser M, Kessler H, Graeff H, Müller M, Schmitt M, Luther T. Magdolen V, et al. Among authors: luther t. Biol Chem. 1998 Feb;379(2):157-65. doi: 10.1515/bchm.1998.379.2.157. Biol Chem. 1998. PMID: 9524067
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